公开(公告)号：US20190015452A1

公开(公告)日：2019-01-17

申请号：US15749766

申请日：2016-08-03

Applicant: OSAKA UNIVERSITY ,  ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Kohji NISHIDA ,  Ryuuhei HAYASHI ,  Yoichi HONMA ,  Toru OKUBO ,  Shun SHIBATA

IPC: A61K35/28 ,  A61P27/02 ,  C12N5/0775 ,  C12N5/00

Abstract: The present invention relates to mesenchymal stem cell-derived microparticles having activity that promotes the growth of corneal epithelial stem cells and/or corneal epithelial cells, activity that maintains corneal epithelial stem cells in an undifferentiated state or promotes the formation of colonies thereby, and function that protects corneal epithelium.