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公开(公告)号:US09644025B2
公开(公告)日:2017-05-09
申请号:US12738396
申请日:2008-10-17
申请人: Ronald Black , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Jack Steven Jacobsen , Davinder Gill , Lioudmila Tchistiakova , Angela Widom
发明人: Ronald Black , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Jack Steven Jacobsen , Davinder Gill , Lioudmila Tchistiakova , Angela Widom
IPC分类号: A61K39/395 , C07K16/18 , C07K16/28 , G06Q99/00 , A61K39/00
CPC分类号: C07K16/18 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/71 , C07K2317/732 , C07K2317/734 , C07K2317/77 , G06Q99/00
摘要: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered to a patient depends on the ApoE genotype of the patient.
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公开(公告)号:US20130209453A1
公开(公告)日:2013-08-15
申请号:US13642845
申请日:2011-04-22
申请人: Ronald Black , Jack Steven Jacobsen , Lioudmila Tchistiakova , Angela Widom , Davinder Gill , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Wagner Zago , Manuel J. Buttini
发明人: Ronald Black , Jack Steven Jacobsen , Lioudmila Tchistiakova , Angela Widom , Davinder Gill , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Wagner Zago , Manuel J. Buttini
IPC分类号: A61K39/395
CPC分类号: A61K39/3955 , A61K2039/505 , A61K2039/545 , A61K2039/55 , C07K16/18 , C07K2317/24 , C07K2317/34
摘要: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
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公开(公告)号:US20150118223A9
公开(公告)日:2015-04-30
申请号:US13642845
申请日:2011-04-22
申请人: Ronald Black , Jack Steven Jacobsen , Lioudmila Tchistiakova , Angela Widom , Davinder Gill , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Wagner Zago , Manuel J. Buttini , Gene G. Kinney
发明人: Ronald Black , Jack Steven Jacobsen , Lioudmila Tchistiakova , Angela Widom , Davinder Gill , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Wagner Zago , Manuel J. Buttini , Gene G. Kinney
IPC分类号: A61K39/395
CPC分类号: A61K39/3955 , A61K2039/505 , A61K2039/545 , A61K2039/55 , C07K16/18 , C07K2317/24 , C07K2317/34
摘要: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
摘要翻译: 本发明提供了阿尔茨海默病和类似疾病的免疫治疗方法,其中通过测量tau的水平来监测施用的状态。
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公开(公告)号:US20120070379A1
公开(公告)日:2012-03-22
申请号:US13231903
申请日:2011-09-13
申请人: Ronald Black , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Jack Steven Jacobsen , Davinder Gill , Lioudmila Tchistiakova , Angela Widom
发明人: Ronald Black , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Jack Steven Jacobsen , Davinder Gill , Lioudmila Tchistiakova , Angela Widom
IPC分类号: A61K39/395 , G06Q90/00 , A61K39/00 , A61K49/00 , A61P25/28
CPC分类号: C07K16/18 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/71 , C07K2317/732 , C07K2317/734 , C07K2317/77 , G06Q99/00
摘要: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered to a patient depends on the ApoE genotype of the patient.
摘要翻译: 本发明提供了阿尔茨海默病和类似疾病的免疫治疗方法,其中给予患者的方案取决于患者的ApoE基因型。
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公开(公告)号:US09272030B2
公开(公告)日:2016-03-01
申请号:US13642845
申请日:2011-04-22
申请人: Ronald Black , Jack Steven Jacobsen , Lioudmila Tchistiakova , Angela Widom , Davinder Gill , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Wagner Zago , Manuel J. Buttini , Gene G. Kinney
发明人: Ronald Black , Jack Steven Jacobsen , Lioudmila Tchistiakova , Angela Widom , Davinder Gill , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Wagner Zago , Manuel J. Buttini , Gene G. Kinney
IPC分类号: C07K16/18 , A61K39/00 , A61K39/395
CPC分类号: A61K39/3955 , A61K2039/505 , A61K2039/545 , A61K2039/55 , C07K16/18 , C07K2317/24 , C07K2317/34
摘要: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
摘要翻译: 本发明提供了阿尔茨海默病和类似疾病的免疫治疗方法,其中通过测量tau的水平来监测施用的状态。
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公开(公告)号:US20100266505A1
公开(公告)日:2010-10-21
申请号:US12738396
申请日:2008-10-17
申请人: Ronald Black , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Jack Steven Jacobsen , Davinder Gill , Lioudmila Tchistiakova , Angela Widom
发明人: Ronald Black , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Jack Steven Jacobsen , Davinder Gill , Lioudmila Tchistiakova , Angela Widom
IPC分类号: A61K49/06 , A61K39/395
CPC分类号: C07K16/18 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/71 , C07K2317/732 , C07K2317/734 , C07K2317/77 , G06Q99/00
摘要: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered to a patient depends on the ApoE genotype of the patient.
摘要翻译: 本发明提供了阿尔茨海默病和类似疾病的免疫治疗方法,其中给予患者的方案取决于患者的ApoE基因型。
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公开(公告)号:US20090155256A1
公开(公告)日:2009-06-18
申请号:US12253929
申请日:2008-10-17
申请人: Ronald Black , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Jack Steven Jacobsen , Davinder Gill , Lioudmila Tchistiakova , Angela Widom
发明人: Ronald Black , Lars Ekman , Ivan Lieberburg , Michael Grundman , James Callaway , Keith M. Gregg , Jack Steven Jacobsen , Davinder Gill , Lioudmila Tchistiakova , Angela Widom
IPC分类号: A61K39/395 , C07K16/00 , C07H21/00 , A61P25/28
CPC分类号: C07K16/18 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/71 , C07K2317/732 , C07K2317/734 , C07K2317/77 , G06Q99/00
摘要: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered to a patient depends on the ApoE genotype of the patient.
摘要翻译: 本发明提供了阿尔茨海默病和类似疾病的免疫治疗方法,其中给予患者的方案取决于患者的ApoE基因型。
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