公开(公告)号：US11079279B2

公开(公告)日：2021-08-03

申请号：US16863140

申请日：2020-04-30

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  G01J3/42 ,  G01N21/71

Abstract: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic method may include projecting a pulsed laser to a suspicious specimen, obtaining first spectrum data on the light collected from the suspicious specimen, projecting the pulsed laser to a non-diseased specimen, obtaining second spectrum data on the light collected from the non-diseased specimen, and determining whether a disease is present in the suspicious specimen from a comparison value of the first spectrum data and the second spectrum data using an artificial neural network.

公开(公告)号：US20240148436A1

公开(公告)日：2024-05-09

申请号：US18065792

申请日：2022-12-14

Applicant: SPECLIPSE, INC

Inventor： Sung Hyun PYUN ,  Wan Ki Min

IPC: A61B18/20 ,  A61B5/00 ,  A61B90/00

CPC classification number: A61B18/20 ,  A61B5/0075 ,  A61B5/0082 ,  A61B90/361 ,  A61B90/37 ,  A61B2018/00577

Abstract: Provided is a method including radiating first guide light, which guides a radiation position of a first pulsed beam, onto a suspicious tissue, receiving a first user input for instructing an output of the first pulsed beam while the first guide light is radiated, applying the first pulsed beam to the suspicious tissue to induce plasma ablation in a first target region corresponding to the radiation point of the first guide light, in response to the first user input, wherein the applying of the first pulsed beam is performed after obtaining first image data obtained by capturing an image of the first guide light and a tissue in a periphery the first guide light while the first guide light is radiated to the suspicious tissue, and obtaining target spectrum data on the plasma ablation, obtaining first disease information, and displaying the first image data and the first disease information.

公开(公告)号：US11892353B2

公开(公告)日：2024-02-06

申请号：US17883724

申请日：2022-08-09

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

CPC classification number: G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/0215 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  F17C2221/033 ,  F17C2227/0164 ,  F17C2227/0185 ,  F17C2227/0339 ,  F17C2227/0348 ,  F17C2227/0358 ,  F17C2265/033 ,  F17C2265/034 ,  F17C2265/037 ,  F17C2265/038 ,  F17C2265/066 ,  F17C2270/0105 ,  G01J2003/423 ,  G01N21/718

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

公开(公告)号：US11422033B2

公开(公告)日：2022-08-23

申请号：US17135675

申请日：2020-12-28

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

公开(公告)号：US11326949B2

公开(公告)日：2022-05-10

申请号：US17084334

申请日：2020-10-29

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

Abstract: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic device may include a laser projection module projecting a pulsed laser to a specimen, a light receiving module receiving a light generated by a plasma ablation induced at the specimen by the pulsed laser, a spectral member receiving and dividing the light generated by the plasma ablation; a sensor array including a plurality of sensors arranged to receive the divided light for each wavelength, and a controller obtaining spectrum data of the light generated by the plasma ablation from a specific exposure period, and determining whether or not the specimen is diseased based on the spectrum data of the light generated by the plasma ablation.