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1.发明授权公开(公告)号：US12072291B2
公开(公告)日：2024-08-27
申请号：US17292985
申请日：2019-11-14
发明人： Volker Sturm
CPC分类号： G01N21/718 , G01J3/443 , G01N21/15 , G01N21/33 , G01N2021/151 , G01N2021/335
摘要： A device may be provided for element analysis of materials by means of optical emission spectroscopy, particularly by means of laser-induced plasma spectroscopy, said device having: means for exciting a plasma from a partial quantity of a test sample made of the material to be analyzed; means for detecting and for spectral analysis of optical radiation emitted from the plasma; beam guidance means for guiding at least a part of the optical radiation emitted from the plasma to the means for detecting and spectral analysis; and means for flushing at least one partial region of the device with an inert gas, wherein the beam guidance means are at least one capillary tube, which additionally serves to guide the inert gas. A method may be provided for element analysis of materials by means of optical emission spectroscopy using the device.
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2.发明公开公开(公告)号：US20240264146A1
公开(公告)日：2024-08-08
申请号：US18566380
申请日：2022-06-03
IPC分类号： G01N33/497 , G01J3/443 , G01N1/44 , G01N21/67 , G06V10/774 , G06V20/69
CPC分类号： G01N33/4975 , G01J3/443 , G01N1/44 , G01N21/67 , G06V10/774 , G06V20/69
摘要： The present invention relates to instruments and processes for detecting compounds in gas samples. In particular, for detecting health disorders from biological samples, more preferably for detecting diseases from breath samples of a mammal. It is included among the methods and instruments for the diagnosis of COVID-19.
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公开(公告)号：US12002185B2
公开(公告)日：2024-06-04
申请号：US17309027
申请日：2019-06-10
发明人： Peiyi Zhang , Fang Huang , Sheng Liu
CPC分类号： G06T3/4046 , G01J3/2823 , G01J3/443 , G01N21/6428 , G01N21/6458 , G06N3/08
摘要： A fluorescent single molecule emitter simultaneously transmits its identity, location, and cellular context through its emission patterns. A deep neural network (DNN) performs multiplexed single-molecule analysis to enable retrieving such information with high accuracy. The DNN can extract three-dimensional molecule location, orientation, and wavefront distortion with precision approaching the theoretical limit of information content of the image which will allow multiplexed measurements through the emission patterns of a single molecule.
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公开(公告)号：US11948774B2
公开(公告)日：2024-04-02
申请号：US17223941
申请日：2021-04-06
发明人： Bahram Alizadeh , Martin Lopez
CPC分类号： H01J37/32045 , G01J3/443 , G01N21/67 , G01N21/68 , H01J37/32018 , H01J37/32449 , H01J37/32926 , H01J37/32935 , H01J37/32981 , H05H1/0037 , H05H1/4697 , H01J37/32568 , H01J37/32972 , H01J37/3299 , H01J2237/334
摘要： Methods and apparatus for determination of the gas composition of a sample gas using glow discharge optical emission spectroscopy, in which the method comprises: generating one or more oscillating electromagnetic fields within a plasma cell to excite particles within the cell, to produce a glow discharge plasma in the plasma cell, and controlling the operating conditions for the plasma cell while flowing a gas mixture through the plasma cell to maintain glow discharge optical emissions from the plasma within a desired operating range; and monitoring one or more glow discharge optical emissions from the plasma in the plasma cell by measuring the optical emissions, or measuring a signal that correlates with the optical emissions, at twice the plasma excitation frequency; and processing the signal during each excitation cycle of the electromagnetic excitation, to determine the concentration of a gas within a gas mixture flowing through the plasma cell.
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5.发明授权公开(公告)号：US11940325B2
公开(公告)日：2024-03-26
申请号：US17870051
申请日：2022-07-21
IPC分类号： G01J3/02 , B22F10/20 , B22F10/25 , B22F10/28 , B22F12/44 , B22F12/45 , B22F12/90 , B33Y50/02 , G01J3/36 , G01J3/443 , B22F10/30 , B22F10/366 , B22F10/38 , B33Y10/00 , G01J3/12
CPC分类号： G01J3/36 , B22F10/20 , B22F10/25 , B22F10/28 , B22F12/44 , B22F12/45 , B22F12/90 , B33Y50/02 , G01J3/0208 , G01J3/443 , B22F10/30 , B22F10/366 , B22F10/38 , B33Y10/00 , G01J2003/1213
摘要： Embodiments of the systems can be configured to receive electromagnetic emissions of a substrate (e.g., a build material of a part being made via additive manufacturing) by a detector (e.g., a multi-spectral sensor) and generate a ratio of the electromagnetic emissions to perform spectral analysis with a reduced dependence on location and orientation of a surface of the substrate relative to the multi-spectral sensor. The additive manufacturing process can involve use of a laser to generate a laser beam for fusion of the build material into the part. The system can be configured to set the multi-spectral sensor off-axis with respect to the laser (e.g., an optical path of the multi-spectral sensor is at an angle that is different than the angle of incidence of the laser beam). This can allow the multi-spectral sensor to collect spectral data simultaneously as the laser is used to build the part.
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公开(公告)号：US11927482B2
公开(公告)日：2024-03-12
申请号：US17604814
申请日：2020-03-27
发明人： Kin Pong Lo , Lara Hawrylchak , Malcolm J. Bevan , Theresa Kramer Guarini , Wei Liu , Bernard L. Hwang
CPC分类号： G01J3/10 , G01J3/0218 , G01J3/443 , G01J2003/2879
摘要： One or more embodiments described herein generally relate to systems and methods for calibrating an optical emission spectrometer (OES) used for processing semiconductor substrates. In embodiments herein, a light fixture is mounted to a plate within a process chamber. A light source is positioned within the light fixture such that it provides an optical path that projects directly at a window through which the OES looks into the process chamber for its reading. When the light source is on, the OES measures the optical intensity of radiation from the light source. To calibrate the OES, the optical intensity of the light source is compared at two separate times when the light source is on. If the optical intensity of radiation at the first time is different than the optical intensity of radiation at the second time, the OES is modified.
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公开(公告)号：US11917744B2
公开(公告)日：2024-02-27
申请号：US17383060
申请日：2021-07-22
CPC分类号： H05H1/28 , H01J49/0468 , H01J49/105 , H05H1/4652 , G01J3/443
摘要： A system for cooling an inductively coupled plasma (ICP) instrument includes: the ICP instrument; a pump in fluid communication with the instrument via a first conduit; and a micro-channel heat exchanger in fluid communication with the instrument via a second conduit, and in fluid communication with the pump via a third conduit. The pump is configured to generate a pump outlet pressure of coolant that exceeds a back pressure of the instrument such that a pressure of the coolant traveling through the second conduit and into the heat exchanger is less than or equal to 5 pounds per square inch (psi) above atmospheric pressure, as measured at an inlet to the heat exchanger.
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公开(公告)号：US20240062334A1
公开(公告)日：2024-02-22
申请号：US18493899
申请日：2023-10-25
发明人： Peiyi Zhang , Fang Huang , Sheng Liu
CPC分类号： G06T3/4046 , G01J3/2823 , G01J3/443 , G01N21/6428 , G01N21/6458 , G06N3/08
摘要： A fluorescent single molecule emitter simultaneously transmits its identity, location, and cellular context through its emission patterns. A deep neural network (DNN) performs multiplexed single-molecule analysis to enable retrieving such information with high accuracy. The DNN can extract three-dimensional molecule location, orientation, and wavefront distortion with precision approaching the theoretical limit of information content of the image which will allow multiplexed measurements through the emission patterns of a single molecule.
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9.发明授权公开(公告)号：US11892353B2
公开(公告)日：2024-02-06
申请号：US17883724
申请日：2022-08-09
申请人： SPECLIPSE, INC.
发明人： Sung Hyun Pyun , Wan Ki Min
IPC分类号： G01J3/30 , G01J3/443 , B63B25/16 , B63J2/14 , F02M21/02 , F17C6/00 , F17C9/02 , F17C9/04 , G01J3/42 , G01N21/71
CPC分类号： G01J3/443 , B63B25/16 , B63J2/14 , F02M21/0215 , F17C6/00 , F17C9/02 , F17C9/04 , F17C2221/033 , F17C2227/0164 , F17C2227/0185 , F17C2227/0339 , F17C2227/0348 , F17C2227/0358 , F17C2265/033 , F17C2265/034 , F17C2265/037 , F17C2265/038 , F17C2265/066 , F17C2270/0105 , G01J2003/423 , G01N21/718
摘要： Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.
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公开(公告)号：US20240003817A1
公开(公告)日：2024-01-04
申请号：US18343461
申请日：2023-06-28
发明人： André PETERS
摘要： A spark stand assembly for an optical emission spectroscopy includes: a spark stand body on a mounting flange enabling attaching the assembly to a main housing; an exciter in a recess on the body; an elevated portion on the body adjacent the mounting flange; an elongated notch on the body connecting the recess to a passageway through the elevated portion; a spark stand plate on the body to cover the recess, the notch and part of the elevated portion so the recess forms a plasma chamber and the notch forms a path to the passageway. The plate includes an opening exposing part of a sample on the opening for excitation, the opening being spatially aligned with the exciter when the plate is on the body; and a sealing member between the top of the body and the plate enclosing the recess and notch and routed over the elevated portion.
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