公开(公告)号：US09827446B2

公开(公告)日：2017-11-28

申请号：US15388201

申请日：2016-12-22

Applicant: STC.UNM ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Shuang Luan ,  Lijun Ma ,  Zhe Chen

IPC: A61N5/00 ,  A61N5/10 ,  A61B6/00

CPC classification number: A61N5/1084 ,  A61B6/4085 ,  A61N5/10 ,  A61N5/1031 ,  A61N5/1065 ,  A61N5/1067 ,  A61N5/1071 ,  A61N5/1081 ,  A61N2005/1074

Abstract: Photon-based radiosurgery is widely used for treating local and regional tumors. The key to improving the quality of radiosurgery is to increase the dose falloff rate from high dose regions inside the tumor to low dose regions of nearby healthy tissues and structures. Dynamic photon painting (DPP) further increases dose falloff rate by treating a target by moving a beam source along a dynamic trajectory, where the speed, direction and even dose rate of the beam source change constantly during irradiation. DPP creates dose gradient that rivals proton Bragg Peak and outperforms Gamma Knife® radiosurgery.

公开(公告)号：US20230288549A1

公开(公告)日：2023-09-14

申请号：US18055772

申请日：2022-11-15

Applicant: The Regents of the University of California ,  Nanyang Technological University

Inventor： Ziqi Wang ,  Mani Srivastava ,  Akash Deep Singh ,  Luis Garcia ,  Zhe Chen ,  Jun Luo

IPC: G01S13/02 ,  G01S7/41 ,  G01S13/88 ,  G01S7/28 ,  G01S7/292

CPC classification number: G01S13/0209 ,  G01S7/414 ,  G01S13/888 ,  G01S7/2813 ,  G01S7/2923

Abstract: Systems and methods for simultaneously recovering and separate sounds from multiple sources using Impulse Radio Ultra-Wideband (IR-UWB) signals are described. In one embodiment, a device can be configured for generating an audio signal based on audio source ranging using ultrawideband signals. In an embodiment the device includes, a transmitter circuitry, a receiver circuitry, memory and a processor. The processor configured to generate a radio signal. The radio signal including an ultra-wideband Gaussian pulse modulated on a radio-frequency carrier. The processor further configured to transmit the radio signal using the transmitter circuitry, receive one or more backscattered signals at the receiver circuitry, demodulate the one or more backscattered signals to generate one or more baseband signals, and generate a set of data frames based on the one or more baseband signals.

公开(公告)号：US09561389B2

公开(公告)日：2017-02-07

申请号：US15179289

申请日：2016-06-10

Applicant: STC.UNM

Inventor： Shuang Luan ,  Lijun Ma ,  Zhe Chen

IPC: A61N5/00 ,  A61N5/10

CPC classification number: A61N5/1084 ,  A61B6/4085 ,  A61N5/10 ,  A61N5/1031 ,  A61N5/1065 ,  A61N5/1067 ,  A61N5/1071 ,  A61N5/1081 ,  A61N2005/1074

Abstract: Photon-based radiosurgery is widely used for treating local and regional tumors. The key to improving the quality of radiosurgery is to increase the dose falloff rate from high dose regions inside the tumor to low dose regions of nearby healthy tissues and structures. Dynamic photon painting (DPP) further increases dose falloff rate by treating a target by moving a beam source along a dynamic trajectory, where the speed, direction and even dose rate of the beam source change constantly during irradiation. DPP creates dose gradient that rivals proton Bragg Peak and outperforms Gamma Knife® radiosurgery.

Abstract translation: 基于光子的放射外科手术广泛用于治疗局部和局部肿瘤。 提高放射外科手术质量的关键是提高肿瘤内部高剂量区域到附近健康组织和结构的低剂量区域的剂量衰减率。 动态光子绘画（DPP）通过沿着动态轨迹移动光束源来处理目标物体进一步增加剂量衰减速率，其中光束源的速度，方向和均匀剂量率在照射期间不断变化。 DPP产生与质子Bragg峰值相当的剂量梯度，并优于GammaKnife®放射外科手术。