公开(公告)号：US20170197983A1

公开(公告)日：2017-07-13

申请号：US15467548

申请日：2017-03-23

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Tatsuki KOIKE ,  Yuichi KAJITA ,  Masato YOSHIKAWA ,  Shuhei IKEDA ,  Eiji KIMURA ,  Tomoaki HASUI ,  Toshiya NISHI ,  Hiromi FUKUDA

IPC: C07D498/08 ,  C07D413/14 ,  C07D417/14 ,  C07D471/08 ,  C07D471/10 ,  C07D405/14 ,  C07D213/74 ,  C07D239/42 ,  C07D401/04 ,  C07D401/14 ,  C07D487/18

CPC classification number: C07D498/08 ,  A61K9/2018 ,  A61K9/4858 ,  C07D213/12 ,  C07D213/72 ,  C07D213/74 ,  C07D239/42 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14 ,  C07D451/02 ,  C07D451/04 ,  C07D471/08 ,  C07D471/10 ,  C07D487/08 ,  C07D487/10 ,  C07D487/18 ,  C07D491/08 ,  C07D491/18 ,  C12N9/99

Abstract: An object of the present invention is to provide a compound having a superior CH24H inhibitory action, which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.

公开(公告)号：US20150315209A1

公开(公告)日：2015-11-05

申请号：US14650429

申请日：2013-12-10

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Tatsuki KOIKE ,  Yuichi KAJITA ,  Masato YOSHIKAWA ,  Shuhei IKEDA ,  Eiji KIMURA ,  Tomoaki HASUI ,  Toshiya NISHI ,  Hiromi FUKUDA

IPC: C07D498/08 ,  C07D413/14 ,  C07D417/14 ,  C07D403/04 ,  C07D405/14 ,  C07D471/10 ,  C07D401/04 ,  C07D401/14 ,  C07D471/08

CPC classification number: C07D498/08 ,  A61K9/2018 ,  A61K9/4858 ,  C07D213/12 ,  C07D213/72 ,  C07D213/74 ,  C07D239/42 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14 ,  C07D451/02 ,  C07D451/04 ,  C07D471/08 ,  C07D471/10 ,  C07D487/08 ,  C07D487/10 ,  C07D487/18 ,  C07D491/08 ,  C07D491/18 ,  C12N9/99

Abstract: An object of the present invention is to provide a compound having a superior CH24H inhibitory action, which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.

Abstract translation: 本发明的目的是提供具有优异CH24H抑制作用的化合物，其可用作预防或治疗癫痫，神经变性疾病等的药剂。 本发明涉及由下式表示的化合物：其中每个符号如说明书中所定义，或其盐。