公开(公告)号：US20190201560A1

公开(公告)日：2019-07-04

申请号：US16325376

申请日：2017-09-06

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Philip Hong-Sean Chao ,  R. Michael van Dam

IPC: A61K51/02 ,  A61B6/03 ,  B01L3/00

CPC classification number: A61K51/02 ,  A61B6/037 ,  A61K51/0446 ,  A61K51/0459 ,  A61K51/0491 ,  B01L3/502753 ,  B01L2300/0681 ,  B01L2300/0883 ,  B01L2300/12 ,  C07B59/00

Abstract: A method of formulating or concentrating a radiolabeled molecule or compound includes providing a microfluidic device having a sample layer containing a microfluidic channel formed therein, a porous membrane having a pore size of less than 0.5 μm disposed on the sample layer and covering the microfluidic channel, and a gas flow layer having a gas-carrying channel formed therein, wherein the porous membrane is interposed between the sample layer and the gas flow layer. A fluid containing the radiolabeled molecule or compound is delivered into the microfluidic channel. Heat is applied to evaporate the fluid. A gas is passed through gas-carrying channel to remove evaporated fluid from the microfluidic device.