公开(公告)号：US20140298990A1

公开(公告)日：2014-10-09

申请号：US14357157

申请日：2012-11-08

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Inventor： Xudong Fan ,  Yogesh B. Gianchandani ,  Jing Liu

IPC: G01N30/46

CPC classification number: G01N30/461 ,  G01N30/46 ,  G01N30/463 ,  G01N30/465 ,  G01N30/466 ,  G01N30/468 ,  G01N30/6095 ,  G01N30/72

Abstract: The present disclosure provides adaptive methods for gas chromatography analysis of a gas sample comprising one or more target analytes (such as a micro-gas chromatography) and adaptive gas chromatography devices for carrying out such analytical methods. Broadly, the system can regulate flow into a downstream chromatographic column by detecting one or more upstream conditions. For example, one adaptive chromatography device comprises a first column, a modulator component, and a second column. A first detector or sensor detects the presence of target analytes upstream from the second column, while a second detector detects the presence of target analytes eluted from the second column. The modulator component assembly is responsive to an output generated by the first detector and adaptively regulates fluid flow into the second column. Such adaptive chromatography (micro-GC) systems have higher separation speed, better analyte identification capability, and far greater energy savings.

Abstract translation: 本公开提供了用于气体样品的气相色谱分析的自适应方法，所述气体样品包含一种或多种靶分析物（例如微气相色谱）和用于进行这种分析方法的适应性气相色谱装置。 通常，系统可以通过检测一个或多个上游条件来调节流入下游色谱柱的流量。 例如，一个自适应色谱装置包括第一列，调制器组件和第二列。 第一检测器或传感器检测来自第二列上游的目标分析物的存在，而第二检测器检测从第二列洗脱的目标分析物的存在。 调制器部件组件响应于由第一检测器产生的输出并且自适应地调节流入第二列的流体流。 这种自适应色谱（micro-GC）系统具有更高的分离速度，更好的分析物识别能力和更大的能量节省。

公开(公告)号：US09341604B2

公开(公告)日：2016-05-17

申请号：US14357157

申请日：2012-11-08

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Inventor： Xudong Fan ,  Yogesh B. Gianchandani ,  Jing Liu

IPC: G01N30/46 ,  G01N30/60 ,  G01N30/72

CPC classification number: G01N30/461 ,  G01N30/46 ,  G01N30/463 ,  G01N30/465 ,  G01N30/466 ,  G01N30/468 ,  G01N30/6095 ,  G01N30/72

Abstract: The present disclosure provides adaptive methods for gas chromatography analysis of a gas sample comprising one or more target analytes (such as a micro-gas chromatography) and adaptive gas chromatography devices for carrying out such analytical methods. Broadly, the system can regulate flow into a downstream chromatographic column by detecting one or more upstream conditions. For example, one adaptive chromatography device comprises a first column, a modulator component, and a second column. A first detector or sensor detects the presence of target analytes upstream from the second column, while a second detector detects the presence of target analytes eluted from the second column. The modulator component assembly is responsive to an output generated by the first detector and adaptively regulates fluid flow into the second column. Such adaptive chromatography (micro-GC) systems have higher separation speed, better analyte identification capability, and far greater energy savings.

Abstract translation: 本公开提供了用于气体样品的气相色谱分析的自适应方法，所述气体样品包含一种或多种靶分析物（例如微气相色谱）和用于进行这种分析方法的适应性气相色谱装置。 通常，系统可以通过检测一个或多个上游条件来调节流入下游色谱柱的流量。 例如，一个自适应色谱装置包括第一列，调制器组件和第二列。 第一检测器或传感器检测来自第二列上游的目标分析物的存在，而第二检测器检测从第二列洗脱的目标分析物的存在。 调制器部件组件响应于由第一检测器产生的输出并且自适应地调节流入第二列的流体流。 这种自适应色谱（micro-GC）系统具有更高的分离速度，更好的分析物识别能力和更大的能量节省。