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公开(公告)号:US20060258571A1
公开(公告)日:2006-11-16
申请号:US10522667
申请日:2003-07-18
申请人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Hein-Peter Kroll , Franz Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand
发明人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Hein-Peter Kroll , Franz Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand
IPC分类号: A61K38/12 , A61K31/395 , C07K5/12
CPC分类号: C07K5/0812 , A61K38/00
摘要: The invention relates to antibacterial ester macrocycles of formula (I), methods for the production thereof, and the use thereof for producing medicaments used for the treatment and/or prophylaxis of diseases, particularly bacterial infections.
摘要翻译: 本发明涉及式(I)的抗菌酯大环化合物,其制备方法及其用于制备用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US20050256037A1
公开(公告)日:2005-11-17
申请号:US10957489
申请日:2004-10-01
申请人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Hein-Peter Kroll , Franz Von Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand
发明人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Hein-Peter Kroll , Franz Von Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand
CPC分类号: C07K5/0812 , A61K38/00
摘要: The invention relates to antibacterial amide macrocycles and process for their preparation, their use for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially of bacterial infections.
摘要翻译: 本发明涉及抗菌酰胺大环化合物及其制备方法,其用于治疗和/或预防疾病的用途及其用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US20070129288A1
公开(公告)日:2007-06-07
申请号:US10518600
申请日:2003-06-10
申请人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Heinz-Peter Kroll , Franz Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Canco-Grande , Martin Michels , Stefan Weigand
发明人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Heinz-Peter Kroll , Franz Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Canco-Grande , Martin Michels , Stefan Weigand
CPC分类号: C07D245/04 , A61K38/00 , C07K5/0812
摘要: The invention relates to antibacterial amide macrocycles, to methods for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of illness, especially bacterial infections.
摘要翻译: 本发明涉及抗菌酰胺大环化合物,其生产方法及其用于制备用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US20070099885A1
公开(公告)日:2007-05-03
申请号:US11453375
申请日:2006-06-15
申请人: Rainer Endermann , Kerstin Ehlert , Siegfried Raddatz , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand , Isabelle Adelt , Thomas Lampe
发明人: Rainer Endermann , Kerstin Ehlert , Siegfried Raddatz , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand , Isabelle Adelt , Thomas Lampe
IPC分类号: A61K31/395 , C07D471/04
CPC分类号: C07K7/06 , C07K5/0812 , C07K5/1016
摘要: The invention relates to antibacterial macrocycles with substituted biphenyl and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially of bacterial infections.
摘要翻译: 本发明涉及具有取代联苯的抗菌大环化合物及其制备方法,其用于治疗和/或预防疾病的用途,以及用于生产用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US07655643B2
公开(公告)日:2010-02-02
申请号:US11453375
申请日:2006-06-15
申请人: Rainer Endermann , Kerstin Ehlert , Siegfried Raddatz , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand , Isabelle Adelt , Thomas Lampe
发明人: Rainer Endermann , Kerstin Ehlert , Siegfried Raddatz , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand , Isabelle Adelt , Thomas Lampe
IPC分类号: A01N43/00 , A61K31/33 , C07D487/00
CPC分类号: C07K7/06 , C07K5/0812 , C07K5/1016
摘要: The invention relates to antibacterial macrocycles with substituted biphenyl and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially of bacterial infections.
摘要翻译: 本发明涉及具有取代联苯的抗菌大环化合物及其制备方法,其用于治疗和/或预防疾病的用途及其用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US07446102B2
公开(公告)日:2008-11-04
申请号:US11690762
申请日:2007-03-23
申请人: Rainer Endermann , Kerstin Ehlert , Christoph Freiberg , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Joachim Schuhmacher , Stefan Weigand
发明人: Rainer Endermann , Kerstin Ehlert , Christoph Freiberg , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Joachim Schuhmacher , Stefan Weigand
CPC分类号: C07K7/06 , A61K38/00 , C07K5/0812 , C07K5/1016 , Y02A50/475 , Y02A50/481
摘要: The invention relates to antibacterial amide macrocycles and processes for their preparation, their use for the treatment and/or prophylaxis of diseases and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infections.
摘要翻译: 本发明涉及抗菌酰胺大环化合物及其制备方法,它们用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US20080076745A1
公开(公告)日:2008-03-27
申请号:US11690762
申请日:2007-03-23
申请人: Rainer Endermann , Kerstin Ehlert , Christoph Freiberg , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Joachim Schuhmacher , Stefan Weigand
发明人: Rainer Endermann , Kerstin Ehlert , Christoph Freiberg , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Joachim Schuhmacher , Stefan Weigand
IPC分类号: C07D245/04 , A61K31/395 , A61P31/04
CPC分类号: C07K7/06 , A61K38/00 , C07K5/0812 , C07K5/1016 , Y02A50/475 , Y02A50/481
摘要: The invention relates to antibacterial amide macrocycles and processes for their preparation, their use for the treatment and/or prophylaxis of diseases and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infections.
摘要翻译: 本发明涉及抗菌酰胺大环化合物及其制备方法,它们用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US20080300231A1
公开(公告)日:2008-12-04
申请号:US11904550
申请日:2007-09-26
申请人: Rainer Endermann , Kerstin Ehlert , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Stefan Weigand , Karin Fischer
发明人: Rainer Endermann , Kerstin Ehlert , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Stefan Weigand , Karin Fischer
IPC分类号: A61K31/33 , C07D245/00 , A61P31/00
CPC分类号: C07K5/0202 , C07D245/04 , C07K5/0812 , C07K5/1016 , C07K7/02 , C07K7/06
摘要: The invention relates to antibacterial amide macrocycles and methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular of bacterial infections.
摘要翻译: 本发明涉及抗菌酰胺大环化合物及其制备方法,它们用于治疗和/或预防疾病的用途,以及它们用于生产用于治疗和/或预防疾病,特别是细菌感染的药物的用途 。
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公开(公告)号:US07405201B2
公开(公告)日:2008-07-29
申请号:US10490192
申请日:2002-09-06
申请人: Berthold Hinzen , Heike Brötz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
发明人: Berthold Hinzen , Heike Brötz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
摘要: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
摘要翻译: 本发明涉及通式(I)的化合物,其制备方法,包含它们的药物组合物及其在治疗人或动物疾病中的用途。
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公开(公告)号:US20050107288A1
公开(公告)日:2005-05-19
申请号:US10490192
申请日:2002-09-06
申请人: Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
发明人: Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
摘要: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
摘要翻译: 本发明涉及通式(I)的化合物,其制备方法,包含它们的药物组合物及其在治疗人或动物疾病中的用途。
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