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公开(公告)号：US07402683B2
公开(公告)日：2008-07-22
申请号：US10512724
申请日：2003-04-14
申请人： Nina Brunner , Christoph Freiberg , Thomas Lampe , Ben Newton , Michael Otteneder , Josef Pernerstorfer , Jens Pohlmann , Guido Schiffer , Mitsuyuki Shimada , Niels Svenstrup , Rainer Endermann , Peter Nell
发明人： Nina Brunner , Christoph Freiberg , Thomas Lampe , Ben Newton , Michael Otteneder , Josef Pernerstorfer , Jens Pohlmann , Guido Schiffer , Mitsuyuki Shimada , Niels Svenstrup , Rainer Endermann , Peter Nell
IPC分类号： C07D207/00 , C07D215/38 , C07D213/00 , C07D403/02 , C07D231/00 , A01N43/36 , A01N43/56 , A01N43/40 , A01N43/42
CPC分类号： C07D207/40 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12
摘要： The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection.
摘要翻译： 本发明涉及化合物，其制备方法，包含它们的药物组合物，以及它们在人或动物，特别是细菌感染疾病的治疗和/或预防中的用途。
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公开(公告)号：US20080051424A1
公开(公告)日：2008-02-28
申请号：US11788649
申请日：2007-04-20
申请人： Franz Von Nussbaum , Nina Brunner , Rainer Endermann , Chantal Fuerstner , Elke Hartmann , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruening
发明人： Franz Von Nussbaum , Nina Brunner , Rainer Endermann , Chantal Fuerstner , Elke Hartmann , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruening
IPC分类号： A61K31/506 , A61P31/04 , C07D239/24
CPC分类号： C07K7/06
摘要： The invention relates to nonadepsipeptides and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
摘要翻译： 本发明涉及非吸收肽及其制备方法以及其用于生产用于治疗和/或预防疾病，特别是细菌感染性疾病的药物的用途。
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公开(公告)号：US07727956B2
公开(公告)日：2010-06-01
申请号：US11788690
申请日：2007-04-19
申请人： Franz Von Nussbaum , Nina Brunner , Rainer Endermann , Chantal Fuerstner , Elke Hartmann , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruening
发明人： Franz Von Nussbaum , Nina Brunner , Rainer Endermann , Chantal Fuerstner , Elke Hartmann , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruening
IPC分类号： A61K38/00 , A61K38/12 , A61K39/00 , C07K5/00 , C07K7/00 , C07K7/54 , C07K9/00 , C07K16/00 , C07K17/00
摘要： Nonadepsipeptides and methods for their preparation and their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases are described.
摘要翻译： 描述了非吸收肽及其制备方法及其用于生产用于治疗和/或预防疾病，特别是细菌感染性疾病的药物的用途。
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公开(公告)号：US07368424B2
公开(公告)日：2008-05-06
申请号：US10840749
申请日：2004-05-06
申请人： Franz Von Nussbaum , Nina Brunner , Sonja Anlauf , Rainer Endermann , Chantal Fürstner , Elke Hartmann , Johannes Köbberling , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Michael-Alexander Bruening
发明人： Franz Von Nussbaum , Nina Brunner , Sonja Anlauf , Rainer Endermann , Chantal Fürstner , Elke Hartmann , Johannes Köbberling , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Michael-Alexander Bruening
CPC分类号： C07K5/06078 , A61K38/00 , C07K5/06026 , C07K5/06043 , C07K5/06069 , C07K7/06 , Y02A50/473 , Y02A50/481
摘要： The invention relates to nonadepsipeptides and process for their preparation, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
摘要翻译： 本发明涉及非肽缩肽及其制备方法，以及它们用于生产药物用于治疗和/或预防疾病，特别是细菌感染性疾病的用途。
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公开(公告)号：US20070129288A1
公开(公告)日：2007-06-07
申请号：US10518600
申请日：2003-06-10
申请人： Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Heinz-Peter Kroll , Franz Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Canco-Grande , Martin Michels , Stefan Weigand
发明人： Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Heinz-Peter Kroll , Franz Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Canco-Grande , Martin Michels , Stefan Weigand
CPC分类号： C07D245/04 , A61K38/00 , C07K5/0812
摘要： The invention relates to antibacterial amide macrocycles, to methods for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of illness, especially bacterial infections.
摘要翻译： 本发明涉及抗菌酰胺大环化合物，其生产方法及其用于制备用于治疗和/或预防疾病，特别是细菌感染的药物的用途。
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6.发明申请Method for characterising and/or identifying active mechanisms of antimicrobial test substances 审中-公开用于表征和/或鉴定抗微生物测试物质活性机理的方法公开(公告)号：US20050123917A1
公开(公告)日：2005-06-09
申请号：US10495042
申请日：2002-11-12
CPC分类号： C12Q1/18
摘要： The invention relates to a method for the characterisation and/or identification of active mechanisms of antibacterial test substances, by means of IR (infrared) analyses, FT-IR (Fourier Transform Infrared) analyses, Raman analyses, or FT-Raman (Fourier Transform Raman) analyses.
摘要翻译： 本发明涉及通过IR（红外）分析，FT-IR（傅里叶变换红外）分析，拉曼分析或FT-拉曼（傅立叶变换）来表征和/或鉴定抗菌试验物质的活性机理的方法 拉曼）分析。
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公开(公告)号：US20050075281A1
公开(公告)日：2005-04-07
申请号：US10840749
申请日：2004-05-06
申请人： Franz Von Nussbaum , Nina Brunner , Sonja Anlauf , Rainer Endermann , Chantal Furstner , Elke Hartmann , Johannes Kobberling , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Michael-Alexander Bruning
发明人： Franz Von Nussbaum , Nina Brunner , Sonja Anlauf , Rainer Endermann , Chantal Furstner , Elke Hartmann , Johannes Kobberling , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Michael-Alexander Bruning
CPC分类号： C07K5/06078 , A61K38/00 , C07K5/06026 , C07K5/06043 , C07K5/06069 , C07K7/06 , Y02A50/473 , Y02A50/481
摘要： The invention relates to nonadepsipeptides and process for their preparation, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
摘要翻译： 本发明涉及非肽缩肽及其制备方法，以及它们用于生产药物用于治疗和/或预防疾病，特别是细菌感染性疾病的用途。
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公开(公告)号：US09133165B2
公开(公告)日：2015-09-15
申请号：US14344995
申请日：2012-09-12
申请人： Wilfried Schwab , Guido Schiffer , Kurt Voegtli , Andreas Kyas , Gerd Osswald
发明人： Wilfried Schwab , Guido Schiffer , Kurt Voegtli , Andreas Kyas , Gerd Osswald
IPC分类号： A61K31/496 , C07D401/12 , C07C309/04
CPC分类号： C07D401/12 , A61K31/496 , C07C309/04
摘要： The invention relates to sulfonic acid salts of heterocyclylamide-substituted imidazoles, and to solvates and hydrates thereof, to the use thereof for treating and/or preventing diseases, and to use thereof for producing drugs for treating and/or preventing diseases, in particular for use as antiviral agents, in particular against cytomegaloviruses.
摘要翻译： 本发明涉及杂环基酰胺取代的咪唑的磺酸盐及其溶剂化物和水合物，其用于治疗和/或预防疾病的用途及其用于制备用于治疗和/或预防疾病的药物，特别是用于 用作抗病毒剂，特别是抗巨细胞病毒。
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公开(公告)号：US08076285B2
公开(公告)日：2011-12-13
申请号：US12249888
申请日：2008-10-10
申请人： Franz Von Nussbaum , Hartmut Beck , Nina Brunner , Rainer Endermann , Johannes Koebberling , Jacques Ragot , Joachim Telser , Joachim Schuhmacher , Sonja Anlauf , Yolanda Cancho-Grande , Susanne Greschat , Hans-Christian Militzer , Guido Schiffer
发明人： Franz Von Nussbaum , Hartmut Beck , Nina Brunner , Rainer Endermann , Johannes Koebberling , Jacques Ragot , Joachim Telser , Joachim Schuhmacher , Sonja Anlauf , Yolanda Cancho-Grande , Susanne Greschat , Hans-Christian Militzer , Guido Schiffer
摘要： The invention relates to lysobactin amides and methods for their preparation, as well as their use for manufacturing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
摘要翻译： 本发明涉及溶血酶蛋白酰胺及其制备方法，以及它们用于制备用于治疗和/或预防疾病，特别是细菌感染性疾病的药物的用途。
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公开(公告)号：US20090149528A1
公开(公告)日：2009-06-11
申请号：US12217248
申请日：2008-07-02
申请人： Nina Brunner , Christoph Freiberg , Thomas Lampe , Ben Newton , Michael Otteneder , Joseph Pernerstorfer , Jens Pohlmann , Guido Schiffer , Mitsuyuki Shimada , Niels Svenstrup , Rainer Endermann , Peter Nell
发明人： Nina Brunner , Christoph Freiberg , Thomas Lampe , Ben Newton , Michael Otteneder , Joseph Pernerstorfer , Jens Pohlmann , Guido Schiffer , Mitsuyuki Shimada , Niels Svenstrup , Rainer Endermann , Peter Nell
IPC分类号： A61K31/4025 , C07D207/333 , A61P31/04
CPC分类号： C07D207/40 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12
摘要： The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection.
摘要翻译： 本发明涉及化合物，其制备方法，包含它们的药物组合物，以及它们在人或动物尤其是细菌感染疾病的治疗和/或预防中的用途。
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