公开(公告)号：US08776544B2

公开(公告)日：2014-07-15

申请号：US12712730

申请日：2010-02-25

申请人： Thomas W. McCollough ,  David R. Ducharme ,  Xiaoyong Fu ,  Dennis Schenk

发明人： Thomas W. McCollough ,  David R. Ducharme ,  Xiaoyong Fu ,  Dennis Schenk

IPC分类号： F25D3/02 ,  F25C5/18

CPC分类号： F25D17/065 ,  F25B2700/02 ,  F25C1/08 ,  F25C5/08 ,  F25C5/187 ,  F25C5/22 ,  F25C2400/10 ,  F25C2500/06 ,  F25C2600/04 ,  F25C2700/12 ,  F25D11/022 ,  F25D21/04 ,  F25D21/14 ,  F25D23/066 ,  F25D2317/0651 ,  F25D2317/0661 ,  F25D2317/0666 ,  F25D2317/067 ,  F25D2317/0681 ,  F25D2323/021 ,  F25D2400/40 ,  F25D2700/10 ,  Y10T29/49826 ,  Y10T74/2101 ,  Y10T74/2107 ,  Y10T137/85938

摘要： Provided is a refrigeration appliance including a fresh food compartment for storing food items in a refrigerated environment having a target temperature above zero degrees Centigrade. A freezer compartment is disposed at an elevation vertically below the fresh food compartment for storing food items in a sub-freezing environment having a target temperature below zero degrees Centigrade. The refrigeration appliance also includes one or more of a hand-removable insulated cover, a cool air duct for introducing cooled air adjacent an ice bin, and a rearward-sloped catch pan positioned to catch dripping water in said ice maker and direct the dripping water into a drain.

摘要翻译： 本发明提供了一种制冷装置，其包括用于将食品储存在目标温度高于零摄氏度的冷藏环境中的冷藏室。 冷冻室设置在垂直于新鲜食物室下方的高度处，用于将食品储存在目标温度低于零摄氏度的低温环境中。 制冷装置还包括一个或多个可手动拆卸的绝缘盖，用于将冷却的空气引导到冰箱附近的冷空气管道，以及向后倾斜的捕集盘，其定位成捕获所述制冰机中的滴水并引导滴水 进入排水

公开(公告)号：US20100218540A1

公开(公告)日：2010-09-02

申请号：US12712730

申请日：2010-02-25

申请人： Thomas W. McCollough ,  David R. Ducharme ,  Xiaoyong Fu ,  Dennis Schenk

发明人： Thomas W. McCollough ,  David R. Ducharme ,  Xiaoyong Fu ,  Dennis Schenk

IPC分类号： F25C1/00 ,  F25D13/04 ,  F25D17/04 ,  F25B39/02

CPC分类号： F25D17/065 ,  F25B2700/02 ,  F25C1/08 ,  F25C5/08 ,  F25C5/187 ,  F25C5/22 ,  F25C2400/10 ,  F25C2500/06 ,  F25C2600/04 ,  F25C2700/12 ,  F25D11/022 ,  F25D21/04 ,  F25D21/14 ,  F25D23/066 ,  F25D2317/0651 ,  F25D2317/0661 ,  F25D2317/0666 ,  F25D2317/067 ,  F25D2317/0681 ,  F25D2323/021 ,  F25D2400/40 ,  F25D2700/10 ,  Y10T29/49826 ,  Y10T74/2101 ,  Y10T74/2107 ,  Y10T137/85938

摘要： Provided is a refrigeration appliance including a fresh food compartment for storing food items in a refrigerated environment having a target temperature above zero degrees Centigrade. A freezer compartment is disposed at an elevation vertically below the fresh food compartment for storing food items in a sub-freezing environment having a target temperature below zero degrees Centigrade. The refrigeration appliance also includes one or more of a hand-removable insulated cover, a cool air duct for introducing cooled air adjacent an ice bin, and a rearward-sloped catch pan positioned to catch dripping water in said ice maker and direct the dripping water into a drain.

摘要翻译： 本发明提供了一种制冷装置，其包括用于将食品储存在目标温度高于零摄氏度的冷藏环境中的冷藏室。 冷冻室设置在垂直于新鲜食物室下方的高度处，用于将食品储存在目标温度低于零摄氏度的低温环境中。 制冷装置还包括一个或多个可手动拆卸的绝缘盖，用于将冷却的空气引导到冰箱附近的冷空气管道，以及向后倾斜的捕集盘，其定位成捕获所述制冰机中的滴水并引导滴水 进入排水

公开(公告)号：US20110203305A1

公开(公告)日：2011-08-25

申请号：US12712818

申请日：2010-02-25

申请人： Dennis Schenk ,  Xiaoyong Fu

发明人： Dennis Schenk ,  Xiaoyong Fu

IPC分类号： F25C5/18 ,  F25D13/04 ,  F25D17/06

CPC分类号： F25C1/08 ,  F25D17/065 ,  F25D2317/061

摘要： A refrigerator includes a freezer compartment and a fresh food compartment which includes an ice chamber. The ice chamber includes an ice maker which includes a first heat exchanger for producing ice. The ice chamber further includes an ice container, a second heat exchanger, an air moving apparatus, and an enclosed loop passageway. The ice container is for storing ice produced by the ice maker and includes an exterior surface. The second heat exchanger is for controlling temperature at the ice container. The passageway forms an air flow path such that air travels in thermal contact with the second heat exchanger. The air moving apparatus is positioned to move air through the passageway.

摘要翻译： 冰箱包括冷冻室和包括冰室的新鲜食物室。 冰室包括制冰机，其包括用于产生冰的第一热交换器。 冰室还包括冰容器，第二热交换器，空气移动装置和封闭的环路通道。 冰容器用于储存由制冰机产生的冰并且包括外表面。 第二个热交换器用于控制冰箱上的温度。 通道形成空气流动路径，使得空气与第二热交换器热接触地行进。 空气移动装置被定位成使空气移动通过通道。

公开(公告)号：US08820110B2

公开(公告)日：2014-09-02

申请号：US12712818

申请日：2010-02-25

申请人： Dennis Schenk ,  Xiaoyong Fu

发明人： Dennis Schenk ,  Xiaoyong Fu

IPC分类号： F25D3/02 ,  F25C5/18

CPC分类号： F25C1/08 ,  F25D17/065 ,  F25D2317/061

摘要： A refrigerator includes a freezer compartment and a fresh food compartment which includes an ice chamber. The ice chamber includes an ice maker which includes a first heat exchanger for producing ice. The ice chamber further includes an ice container, a second heat exchanger, an air moving apparatus, and an enclosed loop passageway. The ice container is for storing ice produced by the ice maker and includes an exterior surface. The second heat exchanger is for controlling temperature at the ice container. The passageway forms an air flow path such that air travels in thermal contact with the second heat exchanger. The air moving apparatus is positioned to move air through the passageway.

摘要翻译： 冰箱包括冷冻室和包括冰室的新鲜食物室。 冰室包括制冰机，其包括用于产生冰的第一热交换器。 冰室还包括冰容器，第二热交换器，空气移动装置和封闭的环路通道。 冰容器用于储存由制冰机产生的冰并且包括外表面。 第二个热交换器用于控制冰箱上的温度。 通道形成空气流动路径，使得空气与第二热交换器热接触地行进。 空气移动装置被定位成使空气移动通过通道。

公开(公告)号：US08383810B2

公开(公告)日：2013-02-26

申请号：US13323366

申请日：2011-12-12

申请人： Tiruvettipuram K. Thiruvengadam ,  John S. Chiu ,  Xiaoyong Fu ,  Timothy L. McAllister

发明人： Tiruvettipuram K. Thiruvengadam ,  John S. Chiu ,  Xiaoyong Fu ,  Timothy L. McAllister

IPC分类号： C07D205/08 ,  C07H7/02

CPC分类号： C07D205/08 ,  C07H17/02

摘要： A process is provided for preparing azetidinones useful as intermediates in the synthesis of penems and as hypocholesterolemic agents, comprising reacting a β-(substituted-amino)amide, a β-(substituted-amino)acid ester, or a β-(substituted-amino)thiolcarbonic acid ester with a silylating agent and a cyclizing agent selected from the group consisting of alkali metal carboxylates, quaternary ammonium carboxylates, quaternary ammonium hydroxides, quaternary ammonium alkoxides, quaternary ammonium aryloxides and hydrates thereof, or the reaction product of: (i) at least one quaternary ammonium halide and at least one alkali metal carboxylate; or (ii) at least one quaternary ammonium chloride, quaternary ammonium bromide, or quaternary ammonium iodide and at least one alkali metal fluoride, wherein a quaternary ammonium moiety of the cyclizing agent is unsubstituted or substituted by one to four groups independently selected from the group consisting of alkyl, arylalkyl and arylalkyl-alkyl.

摘要翻译： 提供了一种制备氮杂环丁酮的方法，所述氮杂环丁酮可用作半乳聚糖和低胆固醇血症药物的合成中的中间体，包括使（b） - （取代的 - 氨基）酰胺，和（取代的 - 氨基）酸酯， （取代 - 氨基）硫代碳酸酯与甲硅烷基化剂和选自碱金属羧酸盐，季铵羧酸盐，季铵氢氧化物，季铵醇盐，季铵氧化物及其水合物的环化剂或其反应产物 ：（i）至少一种季铵卤化物和至少一种碱金属羧酸盐; 或（ii）至少一种季铵氯化物，季铵溴化物或季铵碘化物和至少一种碱金属氟化物，其中环化剂的季铵部分是未取代的或被一至四个独立地选自 由烷基，芳烷基和芳基烷基 - 烷基组成。

公开(公告)号：US08329905B2

公开(公告)日：2012-12-11

申请号：US12701174

申请日：2010-02-05

申请人： Kelvin H. Yong ,  Ilia A. Zavialov ,  Jianguo Yin ,  Xiaoyong Fu ,  Thiruvettipuram K. Thiruvengadam

发明人： Kelvin H. Yong ,  Ilia A. Zavialov ,  Jianguo Yin ,  Xiaoyong Fu ,  Thiruvettipuram K. Thiruvengadam

IPC分类号： C07F9/40

CPC分类号： C07D405/06 ,  C07F9/58

摘要： This application discloses a novel process for the preparation of phosphonate esters useful as intermediates in the preparation of himbacine analogs, themselves useful as thrombin receptor antagonists. The chemistry taught herein can be exemplified by the following scheme: wherein R9 is selected from alkyl, aryl heteroaryl and arylalkyl groups having 1 to 10 carbon atoms, and R11 is selected independently for each occurrence from alkyl, aryl heteroaryl and arylalkyl groups having 1 to 10 carbon atoms and hydrogen, X2 is Cl, Br, or I; X3 is selected from Cl and Br; and PdLn is a supported palladium metal catalyst or a soluble heterogeneous palladium catalyst. The L-derivatizing reagent is a moiety which converts the alcohol functional group of compound 137D to any leaving group which can be displaced by a triorgano-phosphite phosphonating agent.

摘要翻译： 本申请公开了一种制备膦酸酯的新方法，其可用作制备作为凝血酶受体拮抗剂的替卡宾类似物的中间体。 本文教导的化学实例可以通过以下方案来举例说明：其中R9选自具有1-10个碳原子的烷基，芳基杂芳基和芳基烷基，R11各自独立地选自烷基，芳基杂芳基和具有1至 10个碳原子和氢，X2是Cl，Br或I; X3选自Cl和Br; PdLn是负载型钯金属催化剂或可溶性多相钯催化剂。 L-衍生试剂是将化合物137D的醇官能团转化成可被三有机 - 亚磷酸酯膦酸酯取代的任何离去基团的部分。

公开(公告)号：US20120107134A1

公开(公告)日：2012-05-03

申请号：US12915477

申请日：2010-10-29

申请人： John Wesley Harris, JR. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Xiaoyong Fu

发明人： John Wesley Harris, JR. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Xiaoyong Fu

IPC分类号： F01D5/18 ,  B23P15/02

CPC分类号： F01D5/081 ,  F01D5/18 ,  F05D2240/81 ,  F05D2260/22141 ,  Y02T50/676

摘要： A platform cooling arrangement in a turbine rotor blade having a platform at an interface between an airfoil and a root, wherein the rotor blade includes an interior cooling passage that extends from a connection at the root to the approximate radial height of the platform, wherein, the interior cooling passage comprises a high-pressure coolant region and a low-pressure coolant region, and wherein a pressure side of the platform comprises a topside extending circumferentially from the airfoil to a pressure side slashface. The platform cooling arrangement may include: a platform cavity formed within the pressure side of the platform, a high-pressure connector that connects the platform cavity to the high-pressure coolant region of the interior cooling passage; a low-pressure connector that connects the platform cavity to the low-pressure coolant region of the interior cooling passage; and a pin bank formed within the platform cavity that includes radial pins.

摘要翻译： 涡轮转子叶片中的平台冷却装置，其具有在翼型件和根部之间的界面处的平台，其中所述转子叶片包括从根部的连接部延伸到所述平台的近似径向高度的内部冷却通道， 内部冷却通道包括高压冷却剂区域和低压冷却剂区域，并且其中平台的压力侧包括从翼面周向延伸到压力侧斜面的顶侧。 平台冷却装置可以包括：形成在平台的压力侧内的平台空腔，将平台空腔连接到内部冷却通道的高压冷却剂区域的高压连接器; 将平台腔连接到内部冷却通道的低压冷却剂区域的低压连接器; 以及形成在所述平台腔内的销排，所述销组包括径向销。

公开(公告)号：US08117863B2

公开(公告)日：2012-02-21

申请号：US12254218

申请日：2008-10-20

申请人： Kyle B. Van Meter ,  Dean A. Martin ,  Xiaoyong Fu

发明人： Kyle B. Van Meter ,  Dean A. Martin ,  Xiaoyong Fu

IPC分类号： F25C5/18

CPC分类号： F25C5/22 ,  F25B21/02 ,  F25C1/04 ,  F25D17/065 ,  F25D2317/061 ,  F25D2317/0666 ,  F25D2317/067 ,  F25D2323/021

摘要： An icemaking compartment is provided in the refrigerator compartment of a bottom mount refrigerator. An icemaker is within the icemaking compartment. A cold air duct supplies cold air from the freezer compartment to the icemaker. The cold air duct is formed in the rear wall of the refrigerator. A fan controls the flow of air through the cold air duct. A return air duct is provided to direct a portion of the air from the icemaker back to the freezer compartment. An air vent in the icemaker directs another portion of air into the refrigerator compartment.

摘要翻译： 在底部安装的冰箱的冷藏室中设置制冰室。 制冰室内有一个制冰机。 冷空气管道将冷冻空气从冷冻室提供给制冰机。 冷风导管形成在冰箱的后壁上。 风扇控制通过冷风管道的空气流。 提供回风管道以将一部分空气从制冰机引导回冷冻室。 制冰机中的通风口将另一部分空气引导到冷藏室。

公开(公告)号：US07956189B2

公开(公告)日：2011-06-07

申请号：US11891351

申请日：2007-08-10

申请人： Xiaoming Chen ,  Xiao Chen ,  Jianguo Yin ,  Xiaoyong Fu ,  David J. Blythin ,  Rongze Kuang ,  Ho-Jane Shue ,  Scott Trzaska ,  Chee-Wah Tang ,  Vincenzo Liotta ,  Zaher Shabani

发明人： Xiaoming Chen ,  Xiao Chen ,  Jianguo Yin ,  Xiaoyong Fu ,  David J. Blythin ,  Rongze Kuang ,  Ho-Jane Shue ,  Scott Trzaska ,  Chee-Wah Tang ,  Vincenzo Liotta ,  Zaher Shabani

IPC分类号： C07D215/38

CPC分类号： C07D413/04

摘要： Disclosed are maleate, tosylate, fumarate, and oxalate salts of the compound 5-(1(S)-Amino-2-Hydroxyethyl)-N-[(2,4-Difluorophenyl)-Methyl]-2-[8-Methoxy-2-(Trifluoromethyl)-5-Quinoline]-4-Oxazolecarboxamide, represented by Formula I, and methods of preparing the same.

摘要翻译： 公开了化合物5-（1（S） - 氨基-2-羟乙基）-N - [（2,4-二氟苯基） - 甲基] -2- [8-甲氧基 - 由式I表示的2-（三氟甲基）-5-喹啉啉-4-氧杂二甲酰胺及其制备方法。

公开(公告)号：US07910775B2

公开(公告)日：2011-03-22

申请号：US12253356

申请日：2008-10-17

申请人： Jianguo Yin ,  Xiaoyong Fu ,  Shuyi Zhang ,  Timothy L. McAllister ,  Agnes S. Kim-Meade ,  Jason L. Winters ,  Anantha Sudhakar ,  Doris P. Schumacher

发明人： Jianguo Yin ,  Xiaoyong Fu ,  Shuyi Zhang ,  Timothy L. McAllister ,  Agnes S. Kim-Meade ,  Jason L. Winters ,  Anantha Sudhakar ,  Doris P. Schumacher

IPC分类号： C07C231/02 ,  C07C233/05

CPC分类号： C07D307/52 ,  C07C235/60

摘要： Disclosed is a process for making the compound of formula I: using the compounds of formulas II, Q, and XI or XII: wherein A is selected from the group consisting of Br, Cl and I (with Br being preferred); and R represents (C1-C10)alkyl. Also disclosed are intermediate compounds that are made in the disclosed process.

摘要翻译： 公开了制备式I化合物的方法：使用式II，Q和XI或XII的化合物：其中A选自Br，Cl和I（其中Br优选）; R表示（C1-C10）烷基。 还公开了在所公开的方法中制备的中间体化合物。