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公开(公告)号：US20160046956A1
公开(公告)日：2016-02-18
申请号：US14648053
申请日：2013-11-29
Applicant: Tuan-Hua David Ho , ACADEMIA SINICA
Inventor： Su-May Yu , Shuen-Fang Lo , Liang-Jwu Chen , Tuan-Hua David Ho
CPC classification number: C12N15/8297 , C12N9/0071 , C12N15/8261 , C12N15/8267 , C12N15/8269 , C12N15/8271 , C12N15/8273 , C12Y114/11013 , Y02A40/146
Abstract: The present invention relates to mutant gibberellin 2-oxidase (GA2ox) genes and uses thereof. In particular, the effective mutations disclosed herein can reduce GA2ox enzymatic activity to different extents, leading to various degrees of GA deficient yet beneficial agronomic traits in transgenic plants.
Abstract translation: 本发明涉及突变赤霉素2-氧化酶（GA2ox）基因及其用途。 特别地，本文公开的有效突变可以将GA2ox酶活性降低到不同程度，导致转基因植物中不同程度的GA缺乏但有益的农学性状。
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2.发明授权Method of controlling plant growth and architecture by controlling expression of gibberellin 2-oxidase 有权通过控制赤霉素2-氧化酶的表达来控制植物生长和结构的方法公开(公告)号：US08426677B2
公开(公告)日：2013-04-23
申请号：US12604808
申请日：2009-10-23
Applicant: Su-May Yu , Shuen-Fang Lo , Liang-Jwu Chen , Tuan-Hua David Ho
Inventor： Su-May Yu , Shuen-Fang Lo , Liang-Jwu Chen , Tuan-Hua David Ho
CPC classification number: C12N15/8297 , C12N9/0071 , C12N15/8273
Abstract: Novel gibberellin 2-oxidase (GA2ox) genes were identified. Differential expression of GA2ox genes correlated with flower development, seed germination, tiller growth and other developmental processes. In addition, the early and increased growth of tiller and adventitious root and altered root architecture caused by overexpression of GA2oxs further suggest the pleiotropic role of GA2oxs in controlling growth and architecture in plants such as rice. GA2ox5, GA2ox6 and GA2ox9 were three genes encoding class C20 GA2oxs in rice. Mutants or transgenic rice overexpressing class C20 GA2oxs exhibited a broad range of mutant phenotypes, including semi-dwarfism, increased root system and higher tiller numbers that may favor grain yield. Mutations in the conserved domain III were found to affect the physiological activity of class C20 GA2oxs. Methods are described for controlling plant growth and architecture by controlling gene expression of gibberellin 2-oxidase in the plant.
Abstract translation: 鉴定了新型赤霉素2-氧化酶（GA2ox）基因。 GA2ox基因的差异表达与花的发育，种子发芽，分蘖生长等发育过程相关。 此外，由于GA2ox过表达引起的分蘖和不定根的早期增长和根系的改变进一步表明GA2oxs在控制水稻等植物生长和结构方面具有多方位的作用。 GA2ox5，GA2ox6和GA2ox9是水稻中编码C20 GA2oxs的三个基因。 突变体或转基因水稻超过C20类型的GA2oxs表现出广泛的突变表型，包括半侏儒症，增加的根系和较高的分蘖数，可能有利于谷物产量。 发现保守结构域III中的突变会影响C20类GA2氧化酶的生理活性。 描述了通过控制植物中赤霉素2-氧化酶的基因表达来控制植物生长和结构的方法。
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公开(公告)号：US09725736B2
公开(公告)日：2017-08-08
申请号：US14648053
申请日：2013-11-29
Applicant: Academia Sinica
Inventor： Su-May Yu , Shuen-Fang Lo , Liang-Jwu Chen , Tuan-Hua David Ho
CPC classification number: C12N15/8297 , C12N9/0071 , C12N15/8261 , C12N15/8267 , C12N15/8269 , C12N15/8271 , C12N15/8273 , C12Y114/11013 , Y02A40/146
Abstract: The present invention relates to mutant gibberellin 2-oxidase (GA2ox) genes and uses thereof. In particular, the effective mutations disclosed herein can reduce GA2ox enzymatic activity to different extents, leading to various degrees of GA deficient yet beneficial agronomic traits in transgenic plants.
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