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公开(公告)号:US20100129444A1
公开(公告)日:2010-05-27
申请号:US12696538
申请日:2010-01-29
申请人: Vincent Corvari , George Grandolfi , Alpa Parikh
发明人: Vincent Corvari , George Grandolfi , Alpa Parikh
IPC分类号: A61K31/165 , A61P25/28 , A61P25/24 , A61K9/20
CPC分类号: A61K31/165 , A61K9/1623 , A61K9/2018
摘要: The present invention is related to compositions of modafinil, including compositions of modafinil and one or more diluents, disintegrants, binders and lubricants, and the processes for their preparation thereof.
摘要翻译: 本发明涉及莫达非尼的组合物,包括莫达非尼和一种或多种稀释剂,崩解剂,粘合剂和润滑剂的组合物及其制备方法。
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公开(公告)号:US20080058424A1
公开(公告)日:2008-03-06
申请号:US11981310
申请日:2007-10-31
申请人: Vincent Corvari , George Grandolfi , Alpa Parikh
发明人: Vincent Corvari , George Grandolfi , Alpa Parikh
IPC分类号: A61K31/165 , A61P1/14 , A61P25/00
CPC分类号: A61K31/165 , A61K9/1623 , A61K9/2018
摘要: The present invention is related to compositions of modafinil, including compositions of modafinil and one or more diluents, disintegrants, binders and lubricants, and the processes for their preparation thereof.
摘要翻译: 本发明涉及莫达非尼的组合物,包括莫达非尼和一种或多种稀释剂,崩解剂,粘合剂和润滑剂的组合物及其制备方法。
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公开(公告)号:US07297346B2
公开(公告)日:2007-11-20
申请号:US10155913
申请日:2002-05-23
申请人: Vincent Corvari , George Grandolfi , Alpa Parikh
发明人: Vincent Corvari , George Grandolfi , Alpa Parikh
IPC分类号: A61K9/20
CPC分类号: A61K9/1623 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K31/165 , Y02A50/415
摘要: The present invention is related to compositions of modafinil, including compositions of modafinil and one or more diluents, disintegrants, binders and lubricants, and the processes for their preparation thereof.
摘要翻译: 本发明涉及莫达非尼的组合物,包括莫达非尼和一种或多种稀释剂,崩解剂,粘合剂和润滑剂的组合物及其制备方法。
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公开(公告)号:US07229644B2
公开(公告)日:2007-06-12
申请号:US10243557
申请日:2002-09-13
申请人: Vincent Corvari , George Grandolfi , Alpa Parikh
发明人: Vincent Corvari , George Grandolfi , Alpa Parikh
IPC分类号: A61K9/14
CPC分类号: A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K31/165
摘要: The present invention is related to compositions of modafinil, including compositions of modafinil and one or more diluents, disintegrants, binders and lubricants, and the processes for their preparation thereof.
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公开(公告)号:US06660729B1
公开(公告)日:2003-12-09
申请号:US09698901
申请日:2000-10-27
申请人: David A. Dickason , Piyush R. Patel , Vincent Corvari , Efraim Shek , Joseph L. Herman , Jeffry M. Skell
发明人: David A. Dickason , Piyush R. Patel , Vincent Corvari , Efraim Shek , Joseph L. Herman , Jeffry M. Skell
IPC分类号: A61K3155
CPC分类号: A61K31/403 , A61K31/5513
摘要: A non-aqueous, particle-forming, fused pyrrolocarbazole-containing composition is disclosed. Upon contact with an aqueous medium, the particle-forming composition spontaneously disperses into suspended particles, thereby forming a stable suspension that provides greatly improved bioavailability of orally administered fused pyrrolocarbazole compounds.
摘要翻译: 公开了一种非水性,形成颗粒的,熔融的含有咯咯唑的组合物。 当与水性介质接触时,颗粒形成组合物自发地分散到悬浮颗粒中,从而形成稳定的悬浮液,其提供口服给药的熔融吡咯并咔唑化合物的极大改善的生物利用度。
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公开(公告)号:USRE37516E1
公开(公告)日:2002-01-15
申请号:US09285166
申请日:1999-04-01
申请人: Peter E. Grebow , Vincent Corvari , David Stong
发明人: Peter E. Grebow , Vincent Corvari , David Stong
IPC分类号: A61K3116
CPC分类号: A61K9/16 , A61K9/14 , A61K31/165
摘要: Pharmaceutical compositions comprising modafinil in the form of particles of defined size. The particle size of modafinil can have a significant effect on the potency and safety profile of the drug.
摘要翻译: 药物组合物包含具有规定大小的颗粒形式的莫达非尼。 莫达非尼的粒径可以显着影响药物的效力和安全性。
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公开(公告)号:US06200968B1
公开(公告)日:2001-03-13
申请号:US09368409
申请日:1999-08-05
申请人: David A. Dickason , Piyush R. Patel , Vincent Corvari , Efraim Shek , Joseph L. Herman , Jeffry M. Skell
发明人: David A. Dickason , Piyush R. Patel , Vincent Corvari , Efraim Shek , Joseph L. Herman , Jeffry M. Skell
IPC分类号: A61K3155
CPC分类号: A61K31/403 , A61K31/5513
摘要: A non-aqueous, particle-forming, fused pyrrolocarbazole-containing composition is disclosed. Upon contact with an aqueous medium, the particle-forming composition spontaneously disperses into suspended particles, thereby forming a stable suspension that provides greatly improved bioavailability of orally administered fused pyrrolocarbazole compounds.
摘要翻译: 公开了一种非水性,形成颗粒的,熔融的含有咯咯唑的组合物。 当与水性介质接触时,颗粒形成组合物自发地分散到悬浮颗粒中,从而形成稳定的悬浮液,其提供口服给药的熔融吡咯并咔唑化合物的极大改善的生物利用度。
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公开(公告)号:US5618845A
公开(公告)日:1997-04-08
申请号:US319124
申请日:1994-10-06
申请人: Peter E. Grebow , Vincent Corvari , David Stong
发明人: Peter E. Grebow , Vincent Corvari , David Stong
IPC分类号: A61K9/16 , A61K9/14 , A61K31/16 , A61K31/165 , A61P25/00 , A61P25/24 , A61P25/26 , A61P25/28
CPC分类号: A61K9/16 , A61K31/165 , A61K9/14
摘要: Pharmaceutical compositions comprising modafinil in the form of particles of defined size. The particle size of modafinil can have a significant effect on the potency and safety profile of the drug.
摘要翻译: 药物组合物包含具有规定大小的颗粒形式的莫达非尼。 莫达非尼的粒径可以显着影响药物的效力和安全性。
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