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    Carboxylic acids that are effective against TB
    4.
    发明授权
    Carboxylic acids that are effective against TB 失效
    对结核病有效的羧酸

    公开(公告)号：US5387605A

    公开(公告)日：1995-02-07

    申请号：US69249

    申请日：1993-05-28

    申请人： Wolfgang Beilfuss ,  Karl-Heinz Diehl ,  Heinz Eggensperger ,  Michael Mohr

    发明人： Wolfgang Beilfuss ,  Karl-Heinz Diehl ,  Heinz Eggensperger ,  Michael Mohr

    IPC分类号： A01N39/04 ,  A01N43/08 ,  A01N37/10

    CPC分类号： A01N43/08 ,  A01N39/04

    摘要： The use of carboxylic acids for controlling mycobacteria is described. The carboxylic acids contain compounds with the general formula: ##STR1## in which A is a substituted or unsubstituted Cs-Clo aryl group, A containing no nitrogen atom,R.sup.1 and R.sup.2 each independently of one other are hydrogen or a C.sub.1 -C.sub.3 alkyl group,m is 0 or 1 andn is a number from 0 to 5,and no alkyl sulphonates or alkyl sulphates are present.Said active ingredients may be used in the form of aqueous and/or alcoholic ready-for-use solutions or may be present in the form of concentrates, powders or granular products or applied to a support such as a cloth. Formulations based on said carboxylic acids may also contain other bactericidal active ingredients, synergistic effects arising in some cases.

    摘要翻译： 描述了使用羧酸来控制分枝杆菌。 羧酸含有具有以下通式的化合物：其中A是取代或未取代的C 8 -C 18芳基，不含氮原子的A，R 1和R 2各自独立地是氢或C 1 -C 3烷基 ，m为0或1，n为0至5的数，并且不存在烷基磺酸盐或烷基硫酸盐。 所述活性成分可以以水性和/或醇型即用型溶液的形式使用，或者可以以浓缩物，粉末或颗粒状产品的形式存在或应用于诸如布的载体上。 基于所述羧酸的制剂还可含有其它杀菌活性成分，在一些情况下产生协同效应。

    Preservatives and their use
    5.
    发明授权
    Preservatives and their use 失效
    防腐剂及其用途

    公开(公告)号：US5670160A

    公开(公告)日：1997-09-23

    申请号：US649254

    申请日：1996-01-30

    申请人： Heinz Eggensperger ,  Karl-Heinz Diehl ,  Peter Oltmanns

    发明人： Heinz Eggensperger ,  Karl-Heinz Diehl ,  Peter Oltmanns

    IPC分类号： A01N31/04 ,  A01N39/00 ,  A01N47/44 ,  A61K8/34 ,  A61K8/368 ,  A61K8/43 ,  A61K8/49 ,  A61Q17/00 ,  A01N25/00 ,  A01N25/02

    CPC分类号： A61Q17/005 ,  A01N31/04 ,  A01N39/00 ,  A01N47/44 ,  A61K8/34 ,  A61K8/368 ,  A61K8/43 ,  A61K8/498 ,  A61K2800/524

    摘要： A preservative, for compositions having an aqueous phase, comprising a) 5 to 60% by weight of an organic acid selected from the group consisting of benzoic acid, 4-hydroxybenzoic acid, salicylic acid, formic acid, acetic acid, propionic acid, sorbic acid, undecylenic acid and dehydracetic acid or their mixtures including their sodium, potassium, calcium, magnesium, ammonium and ethanolamine salts b) 10 to 95% by weight of alcohols of the general formulae I, II or III ##STR1## in which R.sub.1 denotes hydrogen, an n-alkyl, iso-alkyl or alkoxy radical having 1 to 3 C atoms, and R.sub.2 and R.sub.3 denote hydrogen or a CH.sub.3 -- or C.sub.2 H.sub.5 -- radical and n has the value of 3 or 4, and c) 0.1 to 20% by weight of one or more poly(hexa-methylenebiguanide) salts of the general formula ##STR2## in which Z represents hydrochloride, acetate, lactate, benzoate, propionate, 4-hydroxybenzoate, sorbate or salicylate; and n has the value of 4 to 6, in combination in a customary carrier or solvent.

    摘要翻译： 一种防腐剂，用于具有水相的组合物，其包含a）5-60重量％的有机酸，其选自苯甲酸，4-羟基苯甲酸，水杨酸，甲酸，乙酸，丙酸，山梨酸 酸，十一碳烯酸和脱氢乙酸或它们的混合物，包括其钠，钾，钙，镁，铵和乙醇胺盐b）10至95重量％的通式I，II或III的醇。 IMAGE>其中R1表示氢，具有1-3个C原子的正烷基，异烷基或烷氧基，R2和R3表示氢或CH3-或C2H5-基，n的值为3或4， 和c）0.1至20重量％的一种或多种通式“IMAGE”的聚（六亚甲基双胍）盐，其中Z表示盐酸盐，乙酸盐，乳酸盐，苯甲酸盐，丙酸盐，4-羟基苯甲酸盐，山梨酸盐或水杨酸盐; 在通常的载体或溶剂中，n的值为4〜6。

    Liquid 1,2-benzoisothiazoline-3-one preparation
    6.
    发明授权
    Liquid 1,2-benzoisothiazoline-3-one preparation 失效
    液体1,2-苯并异噻唑啉-3-酮制备

    公开(公告)号：US5276047A

    公开(公告)日：1994-01-04

    申请号：US10050

    申请日：1993-01-28

    申请人： Heinz Eggensperger ,  Peter Oltmanns ,  Karl-Heinz Scheler ,  Karl-Heinz Diehl

    发明人： Heinz Eggensperger ,  Peter Oltmanns ,  Karl-Heinz Scheler ,  Karl-Heinz Diehl

    IPC分类号： A01N43/80 ,  A61K31/425 ,  C11D1/40 ,  C11D3/34 ,  C11D3/48 ,  D06M13/332 ,  D06M13/352 ,  D06M16/00 ,  A61K31/33

    CPC分类号： C11D3/48 ,  A01N43/80 ,  A61K31/425 ,  C11D1/40 ,  C11D3/349 ,  D06M13/332 ,  D06M13/352 ,  D06M16/00 ,  C11D3/3481

    摘要： The invention relates to a liquid preparation containing 1,2-benzoisothiazoline-3-one (BIT) and amines and optionally containing additional solvents and common additives, and containing as amine one or more amines having the general formula ##STR1## wherein R represents a straight-chained or branched alkyl or alkylene radical having 10 to 14 C atoms; n+m has a value of 4 to 12 and neither n nor m can be zero. The liquid composition, in an amount of at least 0.05 to 0.3% (by weight), can be used in products which contain water or can be diluted with water such as dispersions of synthetic materials, emulsion paints, adhesives, paper-coating materials, textile softening agents, sizing agents, surfactants, detergents, cleaning and polishing agents, spinning baths, coolants or metal working fluids, leather auxiliaries, and silicone and bitumen emulsions, as agent against material destruction caused by microbes.

    摘要翻译： 本发明涉及含有1,2-苯并异噻唑啉-3-酮（BIT）和胺的液体制剂，任选地含有另外的溶剂和常用添加剂，并且含有一种或多种具有通式（*化学结构*）的胺，其中 R表示具有10-14个碳原子的直链或支链烷基或亚烷基; n + m的值为4〜12，n和m都不能为零。 液体组合物的含量为至少0.05-0.3％（重量），可用于含水的产品中，或可用水稀释，如合成材料，乳液漆，粘合剂，纸张涂料， 纺织软化剂，上浆剂，表面活性剂，洗涤剂，清洁和抛光剂，纺丝浴，冷却剂或金属工作流体，皮革助剂和硅氧烷和沥青乳液作为防止由微生物引起的材料破坏的试剂。

    Bis(4-hydroxy-3,5-dialkylbenzyl)cyano-carboxylic acid esters
    7.
    发明授权
    Bis(4-hydroxy-3,5-dialkylbenzyl)cyano-carboxylic acid esters 失效
    双（4-羟基-3,5-二烷基苄基）氰基 - 羧酸酯

    公开(公告)号：US3950382A

    公开(公告)日：1976-04-13

    申请号：US511078

    申请日：1974-10-01

    申请人： Heinz Eggensperger ,  Volker Franzen ,  Karl-Heinz Diehl ,  Wilfred Kloss

    发明人： Heinz Eggensperger ,  Volker Franzen ,  Karl-Heinz Diehl ,  Wilfred Kloss

    IPC分类号： C07C255/53 ,  C08K5/315 ,  C07C121/76

    CPC分类号： C07C255/00 ,  C07C323/00 ,  C08K5/315

    摘要： The reaction of one mole of a Mannich base corresponding to the formula ##SPC1##And one mole of a Mannich base corresponding to the formula ##SPC2##Wherein R.sub.1, R.sub.2, R.sub.4 and R.sub.5 are independently selected from alkyl groups having 1 to 6 carbon atoms and R is alkyl, preferably lower alkyl, with 1 mole of a carboxylic acid ester corresponding to the formula R.sub.3 CH.sub.2 COOR.sub.4 wherein R.sub.3 is --H, --CN or --COOR.sub.4 and R.sub.4 is an alkyl, thioether, oxyether or aralkyl group having up to 20 carbons in the presence of a catalytically effective amount of an alkaline catalyst is useful for preparing compounds corresponding to the formula ##SPC3##The compounds represented by the above formula are useful as stabilizers for synthetic resins, particularly polyolefins. Compounds of the above formula, when R.sub.3 is --CN are novel and may also be prepared by reacting 1 mole of ##SPC4##And 1 mole of ##SPC5##Wherein X is halogen with 1 mole of NCCH.sub.2 COOR.sub.4 in the presence of an alkali metal and an anhydrous inert organic solvent.

    摘要翻译： 对应于对应于式WHEREIN R1，R2，R4和R5的曼尼希碱的式1的曼尼希碱的1摩尔曼尼希碱的反应独立地选自具有1至6个碳原子的烷基，R是烷基，优选 低级烷基，与1摩尔对应于式R3CH2COOR4的羧酸酯，其中R3是-H，-CN或-COOR4，R4是在催化剂存在下具有至多20个碳的烷基，硫醚，氧醚或芳烷基 有效量的碱性催化剂可用于制备相应于式的化合物。由上式表示的化合物可用作合成树脂，特别是聚烯烃的稳定剂。 当R3是-CN时，上式的化合物是新的，也可以通过使1摩尔的X 1为1的X为卤素的1 MOLE与1摩尔的NCCH 2 COOR 4在碱金属和无水惰性有机溶剂的存在下反应来制备。

    Preserving and disinfecting composition
    10.
    发明授权
    Preserving and disinfecting composition 失效
    保存和消毒组合物

    公开(公告)号：US3988452A

    公开(公告)日：1976-10-26

    申请号：US555441

    申请日：1975-03-05

    申请人： Heinz Eggensperger ,  Karl-Heinz Diehl

    发明人： Heinz Eggensperger ,  Karl-Heinz Diehl

    IPC分类号： A01N43/88 ,  C07D285/34 ,  A61K31/54

    CPC分类号： C07D285/34 ,  A01N43/88

    摘要： This invention provides a composition comprising a synergistic combination of (a) a product obtained by reacting formaldehyde with an alcohol selected from benzyl alcohol, a glycol or a glycol mono-alkyl ether, or mixtures of said alcohols, and (b) a 3,5-bis(alkoxyalkyl)-tetrahydro-2H-1,3,5-thiadiazine-2-thione useful in preserving and/or disinfecting industrial fluids, cosmetics and pharmaceutical preparations.

    摘要翻译： 本发明提供一种组合物，其包含（a）通过甲醛与选自苄醇，二醇或二醇单烷基醚或所述醇的混合物的醇反应获得的产物的协同组合，和（b） 可用于工业液体，化妆品和药物制剂的保存和/或消毒的5-双（烷氧基烷基） - 四氢-2H-1,3,5-噻二嗪-2-硫酮。