公开(公告)号：US20170105645A1

公开(公告)日：2017-04-20

申请号：US15292147

申请日：2016-10-13

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Elisha MOSES ,  Jodie Naim FEIL ,  Dominik FRECHE ,  Nava LEVIT-BINNUN

IPC: A61B5/0478 ,  A61N2/00 ,  A61B5/0408

CPC classification number: A61B5/0478 ,  A61B5/04085 ,  A61B5/0476 ,  A61B5/7217 ,  A61N2/004 ,  A61N2/006

Abstract: A system includes an array of electroencephalography (EEG) electrodes for placement on the head of a subject and a transcranial magnetic stimulation (TMS) device. A controller is configured to operate the array of EEG electrodes to acquire a plurality of EEG signals concurrently with operation of the TMS device to apply a TMS pulse to the head of the subject. The controller is further configured to select an initial set of EEG signals from the EEG signals and to fit an initial decreasing rational function of time to a TMS artifact component of each EEG signal of the initial set. The TMS artifact component of each remaining EEG signal is fit to a linear combination of the initial decreasing rational functions. Each EEG signal is corrected by removing from the EEG signal the function that is fit to the TMS artifact component of the EEG signal.

公开(公告)号：US20200380960A1

公开(公告)日：2020-12-03

申请号：US16767110

申请日：2018-11-26

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Elisha MOSES ,  Tirza BIRON ,  Dominik FRECHE ,  Daniel BAUM ,  Nadav MATALON ,  Netanel EHRMANN ,  Eyal WEINREB

IPC: G10L15/18 ,  G10L15/02 ,  G10L15/05

Abstract: A prosodic speech recognition engine configured to identify prosodic features and patterns in a speech continuum for the extraction of linguistic content including para-syntactic content, discourse function, information structure, meaning, and speaker sentiment.

公开(公告)号：US20150246238A1

公开(公告)日：2015-09-03

申请号：US14714368

申请日：2015-05-18

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Elisha MOSES ,  Assaf Rotem

IPC: A61N2/00 ,  A61B5/0484 ,  A61B5/00 ,  A61N2/02

CPC classification number: A61N2/006 ,  A61B5/0484 ,  A61B5/4836 ,  A61N1/08 ,  A61N1/36025 ,  A61N1/36082 ,  A61N1/40 ,  A61N2/02

Abstract: Transcranial magnetic stimulation (TMS) is a remarkable tool for probing the brain. However, it is still unclear why specific regions in the cortex are excitable by TMS while others are not. This invention provides methods and tools for the design of efficient magnetic stimulators. Such stimulators can excite neuronal networks that were not sensitive to stimulation until now. Stimulation can be carried out both in-vitro and in-vivo. Novel systems and techniques of this invention will enable both treatment and diagnostics by stimulating regions of the brain or neuronal assemblies that were previously unaffected by TMS.

Abstract translation: 经颅磁刺激（TMS）是探索大脑的显着工具。 然而，仍然不清楚为什么皮质中的特定区域可被TMS兴奋，而其他区域则不是。 本发明提供了用于设计有效的磁刺激器的方法和工具。 这种刺激器可以激发到目前为止对刺激不敏感的神经元网络。 刺激可以在体外和体内进行。 本发明的新型系统和技术将能够通过刺激先前未受TMS影响的脑或神经元组件的区域来实现治疗和诊断。