公开(公告)号：US20150175666A1

公开(公告)日：2015-06-25

申请号：US14408950

申请日：2013-06-25

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Yechiel Shai ,  Avraham Ashkenazi ,  Omri Faingold ,  Avraham Ben Nun ,  Nathali Kaushansky

IPC: C07K14/005 ,  A61K38/16 ,  C12N7/00

CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K38/162 ,  C12N7/00 ,  C12N2740/16033 ,  C12N2740/16111 ,  C12N2740/16122

Abstract: The present invention provides peptides, derivatives and analogs comprising an amino acid sequence HTTWMEWD (SEQ ID NO: 1) derived from the ectodomain of HIV gp41 protein, pharmaceutical compositions comprising same, and uses thereof for therapy of T-cell mediated diseases and disorders.

Abstract translation: 本发明提供了包含衍生自HIV gp41蛋白的胞外域的氨基酸序列HTTWMEWD（SEQ ID NO：1）的肽，衍生物和类似物，包含其的药物组合物及其用于治疗T细胞介导的疾病和病症的用途。