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公开(公告)号：US20100174148A1
公开(公告)日：2010-07-08
申请号：US12725685
申请日：2010-03-17
Applicant: Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
Inventor： Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
IPC: A61B1/32
CPC classification number: A61B17/025 , A61B1/32 , A61B5/4893 , A61B17/0206 , A61B17/0218 , A61B2017/00473 , A61B2017/0262
Abstract: A surgical access system including a tissue distraction assembly and a tissue refraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
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公开(公告)号：US20100174146A1
公开(公告)日：2010-07-08
申请号：US12650271
申请日：2009-12-30
Applicant: Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
Inventor： Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
IPC: A61B1/32
CPC classification number: A61B17/025 , A61B1/32 , A61B5/0488 , A61B17/0218 , A61B17/0293 , A61B17/3421 , A61B90/37 , A61B2017/00261 , A61B2017/0256 , A61B2017/0262 , A61M29/02
Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
Abstract translation: 用于接近外科手术目标部位的系统和相关方法，涉及用于产生初始牵引走廊的初始牵引系统，以及能够将初始牵引走廊分散到次级牵引走廊的组件，并且随后顺序地接收多个牵开器叶片，用于 从第二分离走廊收回，从而为外科手术目标部位创建一个手术走廊，两者都可配备一个或多个电极，用于检测神经结构的存在（以及可能的距离和/或方向），之前 在建立手术目标地点的手术走廊期间和之后。
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公开(公告)号：US20100113884A1
公开(公告)日：2010-05-06
申请号：US12650336
申请日：2009-12-30
Applicant: Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
Inventor： Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
CPC classification number: A61B17/02 , A61B1/32 , A61B5/0492 , A61B5/4893 , A61B5/7405 , A61B5/742 , A61B17/0206 , A61B17/0218 , A61B17/025 , A61B17/0293 , A61B2017/00026 , A61B2017/00039 , A61B2017/0256 , A61B2017/0262
Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
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94.发明授权公开(公告)号：US07657308B2
公开(公告)日：2010-02-02
申请号：US11061184
申请日：2005-02-18
Applicant: Patrick Miles , Scot Martinelli , Jared Arambula , James Gharib , Allen Farquhar , Patrick Flanagan
Inventor： Patrick Miles , Scot Martinelli , Jared Arambula , James Gharib , Allen Farquhar , Patrick Flanagan
CPC classification number: A61B5/04001 , A61B5/4041 , A61B17/1626 , A61B17/1671 , A61B17/3472 , A61B17/848 , A61N1/36003 , A61N1/36014
Abstract: The present intention involves systems and related methods for performing dynamic pedicle integrity assessments involving the use of neurophysiology.
Abstract translation: 目前的意图涉及用于执行涉及使用神经生理学的动态椎弓根完整性评估的系统和相关方法。
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95.发明申请System and Methods for Determining Nerve Proximity, Direction, and Pathology During Surgery 有权用于确定手术中神经靠近，方向和病理学的系统和方法公开(公告)号：US20090209879A1
公开(公告)日：2009-08-20
申请号：US12434303
申请日：2009-05-01
Applicant: Norbert F. Kaula , Jeffrey J. Blewett , Goretti Medeiros , James Gharib , Allen Farquhar
Inventor： Norbert F. Kaula , Jeffrey J. Blewett , Goretti Medeiros , James Gharib , Allen Farquhar
IPC: A61B5/0488
CPC classification number: A61B5/4893 , A61B5/04001 , A61B5/0488 , A61B5/1106 , A61B5/4836 , A61B5/7217 , A61B5/743 , A61B17/00 , A61B17/02 , A61B2017/00039 , A61N1/08 , A61N1/36 , A61N1/36017
Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.
Abstract translation: 本发明涉及用于基于神经肌肉反应和引起神经肌肉反应的刺激信号之间确定的关系来确定相对于外科器械的神经接近度，神经方向和病理学的系统和方法。
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Patent Agency Ranking
公开(公告)号：US20090124860A1
公开(公告)日：2009-05-14
申请号：US10789797
申请日：2004-02-27
Applicant: Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
Inventor： Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
IPC: A61B1/32
CPC classification number: A61B17/0206 , A61B1/32 , A61B5/04001 , A61B5/4836 , A61B17/02 , A61B17/0218 , A61B2017/0256
Abstract: A surgical access system including a tissue distraction assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
Abstract translation: 一种包括组织牵引组件和组织缩回组件的手术进入系统，其两者可以装备有一个或多个电极，用于检测神经结构的存在（以及可选的距离和/或方向） 以及在手术目标地点建立手术走廊之后。
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公开(公告)号：US20080097164A1
公开(公告)日：2008-04-24
申请号：US10759811
申请日：2004-01-16
Applicant: Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
Inventor： Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
IPC: A61B1/32
CPC classification number: A61B17/025 , A61B1/32 , A61B5/4893 , A61B17/0206 , A61B17/0218 , A61B2017/00473 , A61B2017/0262
Abstract: A surgical access system including a tissue distraction assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
Abstract translation: 一种包括组织牵引组件和组织缩回组件的手术进入系统，其两者可以装备有一个或多个电极，用于检测神经结构的存在（以及可选的距离和/或方向） 以及在手术目标地点建立手术走廊之后。
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98.发明申请公开(公告)号：US20070016097A1
公开(公告)日：2007-01-18
申请号：US11182545
申请日：2005-07-15
Applicant: Allen Farquhar , James Gharib , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
Inventor： Allen Farquhar , James Gharib , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
CPC classification number: A61B5/0492 , A61B5/0488 , A61B5/05 , A61B5/4893 , A61B90/04 , A61N1/08
Abstract: System (20) and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to determine nerve proximity and nerve direction to surgical instruments (30) employed in accessing a surgical target site.
Abstract translation: 系统（20）和用于执行外科手术和评估的相关方法，包括使用基于神经生理学的监测来确定进入外科手术目标部位的手术器械（30）的神经接近度和神经方向。
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99.发明申请System and methods for determining nerve proximity, direction, and pathology during surgery 有权用于确定手术期间神经接近，方向和病理学的系统和方法公开(公告)号：US20050182454A1
公开(公告)日：2005-08-18
申请号：US10754899
申请日：2004-01-09
Applicant: James Gharib , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
Inventor： James Gharib , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros
CPC classification number: A61B5/4893 , A61B5/04001 , A61B5/0488 , A61B5/1106 , A61B5/4836 , A61B5/7217 , A61B5/743 , A61B17/00 , A61B17/02 , A61B2017/00039 , A61N1/08 , A61N1/36 , A61N1/36017
Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.
Abstract translation: 本发明涉及用于基于神经肌肉反应和引起神经肌肉反应的刺激信号之间确定的关系来确定相对于外科器械的神经接近度，神经方向和病理学的系统和方法。
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100.发明授权
公开(公告)号：US5220920A
公开(公告)日：1993-06-22
申请号：US790669
申请日：1991-11-08
Applicant: James Gharib
Inventor： James Gharib
IPC: A61B5/145 , A61B5/1473 , A61M5/168 , G01N27/27 , G01N27/403 , G01N33/487
CPC classification number: G01N33/48785 , A61M5/1723
Abstract: A system for electrically measuring certain chemical characteristics of electrically-conductive fluids, such as blood, located within a tube and subject to electrical current interference. The measurements are made by measuring the voltage potential between a reference electrode and a sensor electrode sensitive to a particular blood parameter such as pH or calcium, potassium or chloride concentration. A bypass path for the electrical current interference is provided by a pair of noise-reduction electrodes located on opposite sides of the reference and sensor electrodes and interconnected by an amplifier having a relatively low output impedance and a relatively high input impedance. The electrical current interference bypasses the signal electrodes by flowing directly into the amplifier's output terminal, such that the reference and sensor electrodes develop a potential between them that is independent of the electrical current interference.
Abstract translation: 用于电测量位于管内并受到电流干扰的诸如血液的导电流体的某些化学特性的系统。 通过测量对特定血液参数敏感的参考电极和传感器电极之间的电压电位（例如pH或钙，钾或氯化物浓度）进行测量。 用于电流干扰的旁路路径由位于参考电极和传感器电极的相对侧上的一对降噪电极提供，并由具有相对低的输出阻抗和相对高的输入阻抗的放大器互连。 电流干扰通过直接流入放大器的输出端而绕过信号电极，使得参考电极和传感器电极在它们之间形成独立于电流干扰的电位。
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