公开(公告)号：US20210178146A1

公开(公告)日：2021-06-17

申请号：US17180041

申请日：2021-02-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M60/422 ,  A61B5/0215 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00 ,  A61B5/283 ,  A61M60/40 ,  A61M60/50 ,  A61M60/135 ,  A61M60/148 ,  A61M60/205 ,  A61M60/414 ,  A61M60/419 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft, an impeller disposed on the axial shaft, a frame disposed around the impeller, and a motor disposed outside a subject's body, and configured to drive the impeller to pump blood from a distal end of the impeller to a proximal end of the impeller. A drive cable extends from outside the subject's body to the axial shaft, and is configured to impart rotational motion from the motor to the impeller by rotating. The drive cable is held in a preloaded state with respect to the frame, such that initiation of pumping of blood by rotation of the impeller does not cause the drive cable to axially elongate. Other applications are also described.

公开(公告)号：US11033727B2

公开(公告)日：2021-06-15

申请号：US16345389

申请日：2017-11-21

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Ehud Schwammenthal ,  Daniel Glozman ,  Gad Lubinksy

IPC: A61M60/135 ,  A61M60/205 ,  A61M60/40 ,  A61M60/50 ,  A61M60/414 ,  A61M60/833

Abstract: Apparatus and methods are described including a blood pump (24) configured to be placed inside a blood vessel of a in subject, the blood pump including an impeller (28) configured to pump blood by rotating. A support cage (254) is shaped to define a narrow portion (256) that is configured to be disposed around the impeller, and to maintain a separation between a wall of the blood vessel and the impeller, and a radial extension (258) from the narrow portion of the support cage that extends radially outward with respect to the narrow portion of the support cage, the radial extension being configured to substantially maintain a longitudinal axis of the impeller in alignment with a local longitudinal axis of the blood vessel by contacting the wall of the blood vessel. Other applications are also described.

公开(公告)号：US20210170159A1

公开(公告)日：2021-06-10

申请号：US17173944

申请日：2021-02-11

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/829 ,  A61M60/896 ,  A61M60/818 ,  A61M60/419 ,  A61M60/857 ,  A61M60/422

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller, a frame disposed around the impeller, and a distal-tip portion disposed distally with respect to the frame. A duckbill valve is disposed entirely within a distal most 10 mm of the distal-tip portion. The duckbill valve defines a wide inlet and a narrow tip that defines a slit therethrough. The duckbill valve is proximally facing, such that the wide inlet faces a distal end of the distal-tip portion and such that the narrow tip faces away from the distal end of distal-tip portion. Other applications are also described.

公开(公告)号：US20210077676A1

公开(公告)日：2021-03-18

申请号：US16952327

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a left ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject and to pump blood from the left ventricle to an aorta of the subject, by rotating. A frame is disposed around the impeller. A tube is configured to traverse an aortic valve of the subject, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube extends to a distal end of the frame and defines one or more lateral blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. Other applications are also described.

公开(公告)号：US20210069395A1

公开(公告)日：2021-03-11

申请号：US16952444

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A braided element is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.

公开(公告)号：US20210069394A1

公开(公告)日：2021-03-11

申请号：US16952389

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A mesh is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.

公开(公告)号：US20210038792A1

公开(公告)日：2021-02-11

申请号：US17077769

申请日：2020-10-22

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle. A frame is disposed around the impeller, the frame defining generally-cylindrical central portion, and a proximal conical portion that widens from a proximal end of the frame to a proximal end of the generally-cylindrical central portion. A motor drives the impeller to pump blood from the left ventricle to the subject's aorta, by rotation of the impeller. The impeller is configured to be disposed at least partially within the proximal conical portion of the frame during at least some of a time during which the impeller rotates. Other applications are also described.

公开(公告)号：US20210038790A1

公开(公告)日：2021-02-11

申请号：US17069064

申请日：2020-10-13

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus comprising and methods are described including a blood pump that includes an axial shaft, and an impeller disposed on the axial shaft. The impeller is configured to pump blood of the subject by rotating. The impeller and the axial shaft are configured to undergo axial back-and-forth motion during operation of the impeller. A distal tip element is disposed at a distal end of the blood pump. The distal tip element defines an axial-shaft-receiving tube, configured to receive at least a portion of the axial shaft during forward motion of the axial shaft. The distal tip element additionally defines an atraumatic distal tip portion disposed distally of the axial-shaft-receiving tube. Other applications are also described.

公开(公告)号：US20210023288A1

公开(公告)日：2021-01-28

申请号：US17070670

申请日：2020-10-14

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a ventricular assist device that includes a tube configured to traverse a subject's aortic valve. The tube defines a generally-cylindrical central portion, and a proximal conical portion that narrows from a proximal end of the central portion to a proximal end of the tube. The tube defines one or more blood inlet openings in a vicinity of a distal end of the tube, and one or more blood outlet openings that extend axially from the central portion of the tube at least partially into the proximal conical portion of the tube. A blood pump pumps blood into the tube from the subject's left ventricle through the one or more blood inlet openings, and from the tube into the aorta through the one or more blood outlet openings. Other applications are also described.

公开(公告)号：US20200237985A1

公开(公告)日：2020-07-30

申请号：US16810172

申请日：2020-03-05

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M1/12 ,  A61M1/10

Abstract: Apparatus and methods are described including manufacturing a housing for an impeller of a blood pump by placing an inner lining around a mandrel, placing a cylindrical portion of a frame around the inner lining, and placing a distal portion of an elongate tube around a portion of the frame. While the distal portion of the elongate tube is disposed around the portion of the frame, the inner lining, the frame, and the distal portion of the elongate tube are heated, via the mandrel, and pressure is applied from outside the distal portion of the elongate tube, such as to cause the distal portion of the elongate tube to conform with a structure of the struts of the frame, and to cause the inner lining and the distal portion of the elongate tube to become coupled to the frame. Other applications are also described.