公开(公告)号：US20240189571A1

公开(公告)日：2024-06-13

申请号：US18444972

申请日：2024-02-19

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

CPC分类号： A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

摘要： Apparatus and methods are described including a blood pump that includes an impeller configured to be delivered through vasculature of a subject while the impeller is in a radially-constrained configuration. The impeller is configured to self-expand to a non-radially-constrained configuration, and to pump blood while in the non-radially-constrained configuration. A ratio between (a) a diameter of the impeller when the impeller is in its non-radially-constrained configuration at a location at which the diameter of the impeller is at its maximum and (b) a diameter of the impeller when the impeller is in its radially-constrained configuration is greater than 7:2. Other applications are also described.

公开(公告)号：US11666747B2

公开(公告)日：2023-06-06

申请号：US16810116

申请日：2020-03-05

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  B05D1/02 ,  A61M60/808 ,  A61M60/126 ,  A61M60/216 ,  A61M60/237 ,  A61M60/825 ,  A61M60/531 ,  A61M60/13 ,  A61M60/894 ,  A61M60/135 ,  A61M60/818 ,  A61M60/122 ,  A61M60/205

CPC分类号： A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

摘要： Apparatus and methods are described including manufacturing an impeller by forming a structure having first and second bushings at proximal and distal ends that are connected to one another by at least one elongate element. The elongate element is made to radially expand and form a helical elongate element. An elastomeric material is coupled to the helical elongate element, such that the helical elongate element with the elastomeric material coupled thereto defines a blade of the impeller. The coupling is performed such that a layer of the material disposed around a radially outer edge of the helical elongate element forms the effective edge of the impeller blade. A step is performed to enhance bonding of the elastomeric material to the helical elongate element in a manner that does not cause a protrusion from the effective edge of the impeller blade. Other applications are also described.

公开(公告)号：US20220184376A1

公开(公告)日：2022-06-16

申请号：US17682104

申请日：2022-02-28

申请人： MAGENTA MEDICAL LTD.

发明人： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC分类号： A61M60/857 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/419 ,  A61M60/538 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/829

摘要： Apparatus and methods are described including a left-ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle and to pump blood from the left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the aorta and a distal portion of the tube is disposed within the left ventricle. The distal portion of the tube extends to the distal end of the frame and defines more than 10 blood-inlet openings that are sized such as (a) to allow blood to flow from the subject's left ventricle into the tube and (b) to block structures from the subject's left ventricle from entering into the frame. Other applications are also described.

公开(公告)号：US20220079457A1

公开(公告)日：2022-03-17

申请号：US17532318

申请日：2021-11-22

申请人： MAGENTA MEDICAL LTD.

发明人： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC分类号： A61B5/0215 ,  A61M60/226 ,  A61M60/178 ,  A61M60/419 ,  A61M60/531 ,  A61B5/021

摘要： Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject. A driving magnet is coupled to a motor and is rotated by the motor. A driven magnet is magnetically coupled to the driving magnet and is rotated by the driving magnet. A drive cable extends from the driven magnet and imparts rotational motion from the driven magnet to the impeller. A set of sensors is configured to detect a magnetic phase difference between the driven magnet and the driving magnet. A computer processor receives the detected magnetic phase difference and determines a physiological parameter of the subject, at least partially in response thereto. Other applications are also described.

公开(公告)号：US20210052794A1

公开(公告)日：2021-02-25

申请号：US17078439

申请日：2020-10-23

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M1/12 ,  A61M1/10

摘要： Apparatus and methods are described, including a left-ventricular assist device that includes an impeller, and a frame disposed around the impeller, the frame having a length of more than 25 mm when disposed in a non-radially constrained configuration. A rigid axial shaft extends from a proximal end of the frame to a distal end of the frame. A motor is disposed outside a body of a subject, and drives the impeller to pump blood within the subject's body, by rotating. A drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the impeller by rotating. The drive cable is a flexible cable comprising a plurality of coiled wires. Other applications are also described.

公开(公告)号：US20220355096A1

公开(公告)日：2022-11-10

申请号：US17857402

申请日：2022-07-05

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  B05D1/02 ,  A61M60/808 ,  A61M60/126 ,  A61M60/216 ,  A61M60/237 ,  A61M60/825 ,  A61M60/531 ,  A61M60/13 ,  A61M60/894

摘要： Apparatus and methods are described including a blood pump that includes an impeller configured to pump blood through a subject's body, and a frame disposed around the impeller. In a radially-non-constrained configuration of the frame, the frame defines a proximal conical portion and a cylindrical portion disposed distally to the proximal conical portion. During operation of the blood pump, the impeller moves with respect to the frame, and a range of movement of the impeller is such that at least a first portion of the impeller is disposed within the proximal conical portion of the frame during at least some of the operation of the blood pump, and at least a second portion of the impeller is disposed within the cylindrical portion of the frame during at least some of the operation of the blood pump. Other applications are also described.

公开(公告)号：US20220176098A1

公开(公告)日：2022-06-09

申请号：US17677571

申请日：2022-02-22

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/818 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  A61M60/135 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38

摘要： Apparatus and methods are described including a left-ventricular assist device that includes a tube configured to traverse a subject's aortic valve, with a distal portion of the tube within the subject's left ventricle. A frame disposed within the distal portion of the tube defines cells, and a width of each of the cells within a generally cylindrical portion of the frame is less than 2 mm. An inner lining lines at least some of the cylindrical portion of the frame. An impeller is disposed inside the frame. Other applications are also described.

公开(公告)号：US11298523B2

公开(公告)日：2022-04-12

申请号：US16810172

申请日：2020-03-05

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M1/12 ,  A61M1/10 ,  A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/818 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  A61M60/135 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  A61M60/205 ,  A61M60/122

摘要： Apparatus and methods are described including manufacturing a housing for an impeller of a blood pump by placing an inner lining around a mandrel, placing a cylindrical portion of a frame around the inner lining, and placing a distal portion of an elongate tube around a portion of the frame. While the distal portion of the elongate tube is disposed around the portion of the frame, the inner lining, the frame, and the distal portion of the elongate tube are heated, via the mandrel, and pressure is applied from outside the distal portion of the elongate tube, such as to cause the distal portion of the elongate tube to conform with a structure of the struts of the frame, and to cause the inner lining and the distal portion of the elongate tube to become coupled to the frame. Other applications are also described.

公开(公告)号：US20210170159A1

公开(公告)日：2021-06-10

申请号：US17173944

申请日：2021-02-11

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/829 ,  A61M60/896 ,  A61M60/818 ,  A61M60/419 ,  A61M60/857 ,  A61M60/422

摘要： Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller, a frame disposed around the impeller, and a distal-tip portion disposed distally with respect to the frame. A duckbill valve is disposed entirely within a distal most 10 mm of the distal-tip portion. The duckbill valve defines a wide inlet and a narrow tip that defines a slit therethrough. The duckbill valve is proximally facing, such that the wide inlet faces a distal end of the distal-tip portion and such that the narrow tip faces away from the distal end of distal-tip portion. Other applications are also described.

公开(公告)号：US20200237985A1

公开(公告)日：2020-07-30

申请号：US16810172

申请日：2020-03-05

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M1/12 ,  A61M1/10

摘要： Apparatus and methods are described including manufacturing a housing for an impeller of a blood pump by placing an inner lining around a mandrel, placing a cylindrical portion of a frame around the inner lining, and placing a distal portion of an elongate tube around a portion of the frame. While the distal portion of the elongate tube is disposed around the portion of the frame, the inner lining, the frame, and the distal portion of the elongate tube are heated, via the mandrel, and pressure is applied from outside the distal portion of the elongate tube, such as to cause the distal portion of the elongate tube to conform with a structure of the struts of the frame, and to cause the inner lining and the distal portion of the elongate tube to become coupled to the frame. Other applications are also described.