公开(公告)号：US20220143110A1

公开(公告)日：2022-05-12

申请号：US17500606

申请日：2021-10-13

Applicant: Novozymes A/S

Inventor： Derrick Lewis ,  Marianne Thorup Cohn ,  Adam Nelson ,  Preben Nielsen

IPC: A61K35/742 ,  C12N1/20 ,  A23K10/18 ,  A23K50/75 ,  A61P31/04

Abstract: The present invention relates to Bacillus strains which improves health and performance of production animals. The invention further relates to compositions comprising the Bacillus strains.

公开(公告)号：US11326130B2

公开(公告)日：2022-05-10

申请号：US17153082

申请日：2021-01-20

Applicant: NOVOZYMES A/S

Inventor： Christian B. Oehlenschlaeger ,  Dorotea R. Segura ,  Rebecca M. Vejborg ,  Henrik M. Geertz-Hansen ,  Lilian E. T. Baltsen ,  Jesper Salomon

IPC: C12N9/24 ,  C11D3/386 ,  C11D11/00 ,  C11D3/00 ,  C11D3/395

Abstract: The present invention relates to polypeptides having hexosaminidase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

公开(公告)号：US11319509B2

公开(公告)日：2022-05-03

申请号：US16847773

申请日：2020-04-14

Applicant: NOVOZYMES A/S

Inventor： Carsten Andersen ,  Chakshusmathi Ghadiyaram ,  Rajendra Kulothungan Sainathan ,  Padmavathi Balumuri ,  Padma Venkatachalam Iyer ,  Iben Damager ,  Astrid Munch ,  Sohel Dalal

IPC: C12N9/26 ,  C12N9/28 ,  C11D3/386

Abstract: The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20220112478A1

公开(公告)日：2022-04-14

申请号：US17426048

申请日：2020-01-22

Applicant: Novozymes A/S

Inventor： Ane Quesada Ganuza ,  Michael Dolberg Rasmussen ,  Allan Kent Nielsen

IPC: C12N9/90 ,  C12N15/75 ,  C12N9/26 ,  C12N9/42

Abstract: The present invention relates to means and methods for optimizing expression of a heterologous polypeptide of interest in Gram-positive host cells by co-expression with a foldase that is cognate to the heterologous polypeptide of interest.

公开(公告)号：US20220110343A1

公开(公告)日：2022-04-14

申请号：US17556874

申请日：2021-12-20

Applicant: Novozymes A/S

Inventor： Erik Marcussen ,  Poul Erik Jensen

IPC: A23K20/20 ,  A23K40/25 ,  A23K40/20 ,  A23K40/30 ,  A23K20/189

Abstract: The present invention is related to feed granules comprising a feed enzyme and a zinc salt of an organic acid.

公开(公告)号：US11279921B2

公开(公告)日：2022-03-22

申请号：US16603639

申请日：2018-04-10

Applicant: NOVOZYMES A/S

Inventor： Tomoko Namoto ,  Noriko Tsutsumi ,  Keiichi Ayabe ,  Zhengfang Kang

IPC: C12N9/34 ,  C12P19/02 ,  C12P19/14

Abstract: The present invention relates to glucoamylase variants having an increase in raw starch activity compared to the guy-coamylase disclosed as SEQ ID NO: 2, comprising one or more modifications in the catalytic domain and/or one or more modifications in the starch binding domain selected from: a) at least one, preferably at least two, preferably at least three, preferably at least four of: V18M, T43K, N112L, T116R, A117Q, G120S, A271F, Y295W, Q318Y; and/or b) Introducing at least three, preferably at least four substitutions selected from the group: S458C, S458SCGG, S458SGGC, A493V, A518K, E520Q, N527M, S540K, R, S(G)546P, T(V)549W, N503R, N539R+I541Y+T543V+A545S+S546GCGV+G547S+S548T+T549A. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20220064620A1

公开(公告)日：2022-03-03

申请号：US17246266

申请日：2021-04-30

Applicant: Novozymes A/S

Inventor： Frank Winther Rasmussen ,  Peter Kamp Hansen ,  Lars Lehmann Hylling Christensen

IPC: C12N9/54 ,  C11D3/386 ,  C11D17/04 ,  C11D17/00

Abstract: The present invention relates to novel subtilase variants exhibiting increased stability and preferably on par or improved wash performance. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.

公开(公告)号：US20220056387A1

公开(公告)日：2022-02-24

申请号：US17413885

申请日：2019-12-12

Applicant: Novozymes A/S ,  Institute of Microbiology, Chinese Academy of Sciences

Inventor： Wenbing Du ,  Yuxin Qiao ,  Dongwei Chen ,  Shufang Zhao ,  Ming Li ,  Ying Zhang ,  Wanghui Xu ,  Cheng Peng ,  Beiyu Hu ,  Ran Hu

IPC: C12M3/06 ,  C12Q1/37

Abstract: A nanoparticle comprises water-insoluble polymer matrix and an indicator constituent(s), wherein the indicator constituent(s) is released from the nanoparticle only when the polymer matrix is degraded or broken, and then an indicative effect is triggered or enhanced. A nanoparticle-based method for screening a bioactive substance and a microfluidic-based screening system have also been disclosed.

公开(公告)号：US20220031815A1

公开(公告)日：2022-02-03

申请号：US17275801

申请日：2019-09-17

Applicant: DSM IP ASSETS B.V. ,  NOVOZYMES A/S

Inventor： Javier Alejandro AMERI ,  Leticia CARDOSO BITTENCOURT ,  Marcelo HIDALGO ,  Rual LOPEZ-ULIBARRI ,  Vijay MAKHIJA ,  Estefania PEREZ CALVO ,  Rolando VALIENTES

IPC: A61K38/47 ,  A23K20/195 ,  A23K20/189 ,  A23K10/30 ,  A23K50/75 ,  A61K38/12 ,  A61K31/7036 ,  A61K31/43 ,  A61K31/498 ,  A61K31/351 ,  A61K31/4025 ,  A61K31/555 ,  A61K31/7048 ,  A61K31/444 ,  A61K9/00 ,  A61P3/02

Abstract: The present invention provides a composition and/or an animal feed comprising polypeptides having muramidase activity and uses thereof.

公开(公告)号：US20220025300A1

公开(公告)日：2022-01-27

申请号：US17501781

申请日：2021-10-14

Applicant: NOVOZYMES A/S

Inventor： Peter Kamp HANSEN ,  Esben Peter FRIIS ,  Torben Vedel BORCHERT ,  Lars Lehmann Hylling CHRISTENSEN ,  Jens Erik NIELSEN ,  Maria Berggaard SILOW

IPC: C11D3/386 ,  C12N9/54 ,  C11D3/04 ,  C11D3/08

Abstract: The present invention relates to compositions comprising protease variants suitable for use in cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.