摘要:
A retracting animal lead having a housing with a handle portion and an internal chamber in which a spool is rotatably mounted. An extraction opening is formed in the housing in alignment with a winding cylinder of the spool for guiding lead material from the spool out of the housing. The spool is rotationally biased into a first rotational position and is rotatable against the biasing force so as, in use, to unwind from the spool the lead material wound thereon. A winding handle is rotatably mounted to the outside of the housing, and a coupling means is operatively moveable between an engaged position in which it non-rotatable couples the winding handle to the spool so as to enable manual rotation of the spool, thereby, in use, enabling the lead material manually to be rewound onto the spool, and a disengaged position in which the spool in rotationally disconnected from the handle.
摘要:
Improved methods, systems, graphical user interfaces and computer program code for presenting representations or information concerning digital products are disclosed. The representations of digital products can serve to promote certain digital products at an online digital product distribution site. Information concerning a particular digital product can be rapidly accessible from a displayed page at an online digital product distribution site referencing a plurality of different digital products. According to one aspect, a plurality of representations (e.g., images) can be dynamically presented to facilitate access to corresponding digital product information. The representations being presented can be automatically changed on a periodic basis, unless user interaction requests otherwise. According to another aspect, digital product information can be presented in an overlay window that can be initiated by a user and present relevant information concerning a digital product. Advantageously, digital product information can be quickly presented to a user without having to navigate to a new page of an online distribution site.
摘要:
The present invention relates generally to medical devices with therapy eluting components and methods for making same. More specifically, the invention relates to implantable medical devices having at least one porous layer, and methods for making such devices, and loading such devices with therapeutic agents. A mixture or alloy is placed on the surface of a medical device, then one component of the mixture or alloy is generally removed without generally removing the other components of the mixture or alloy. In some embodiments, a porous layer is adapted for bonding non-metallic coating, including drug eluting polymeric coatings. A porous layer may have a random pore structure or an oriented or directional grain porous structure. One embodiment of the invention relates to medical devices, including vascular stents, having at least one porous layer adapted to resist stenosis or cellular proliferation without requiring elution of therapeutic agents. The invention also includes methods, devices, and specifications for loading of drugs and other therapeutic agents into nanoporous coatings.
摘要:
A system and method for efficient electronic communication, which allows the user to address an electronic communication to a plurality of recipients each having a corresponding email address, wherein each of said recipients is assigned to one of a plurality of categories of recipients, and assign a delivery priority to each category of recipients without regard to the identity and number of recipients in each category of recipients, wherein a user is not required to assign a delivery priority to individual recipients.
摘要:
A platform used for capturing knowledge. More specifically, a framework configured to capture expert knowledge (e.g., of trained and/or skilled workers) for future instructional purposes (e.g., training of a younger, or less experienced, workforce). The platform comprises a knowledge recorder, instructional design tool, standardized XML, and gaming engine. The knowledge recorder is configured to capture knowledge of a user, which is transferable using a standardized XML format. The instructional design tool is configured to visually model a gaming scenario in order to expose and define logical situations based on the captured knowledge.
摘要:
A method, computer program, database system and data structure for coding a compressible variable length field in a row to be added to a database table are disclosed. The row has a value to be stored in the compressible variable length field. The value is searched for in a list of values for the compressible variable length field stored in the table. IF the value is found in the list of values, the row is created in the table with a first code associated with the value, a second code associated with a location in the row, but without the compressible variable length field. Otherwise, the row is created in the table with the value stored in the compressible variable length field, a first code indicating that the value is stored in the row, and a second code associated with the location of the value in the row.
摘要:
A compound having Formula I wherein one of R1 and R2 is a group of the formula wherein R4 is selected from H and hydrocarbyl, R5 is a hydrocarbyl group and L is an optional linker group, or R1 and R2 together form a ring substituted with the group wherein R3 is H or a substituent, and wherein X is selected from S, O, NR6 and C(R7)(R8), wherein R6 is selected from H and hydrocarbyl groups, wherein each of R7 and R8 are independently selected from H and hydrocarbyl groups.
摘要翻译:具有式I的化合物,其中R 1和R 2中的一个是下式的基团其中R 4选自H和烃基, R 5是烃基,L是任选的连接基团,或者R 1和R 2一起形成被下列基团取代的环,其中, R 3是H或取代基,其中X选自S,O,NR 6和C(R 7)(R 7) 其中R 6选自H和烃基,其中R 7和R 8中的每一个是 独立地选自H和烃基。
摘要:
System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.
摘要:
The present invention provides a compound comprising a steroidal ring system and an optional group R1 selected from any one of —OH, a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein the A ring of the steroidal ring system is optionally substituted at position 2 or 4 with a group R4 which may be a suitable subtituent, wherein the D ring of the steroidal ring system is substituted by a group R2 of the formula -L-R3, wherein L is an optional linker group and R3 is selected from groups which are or which comprise one of (i) —SO2R5, wherein R5 is H, a hydrocarbyl group or a bond or group attached to the D ring; (ii) —NO2; (iii) —SOR6, wherein R6 is H or a hydrocarbyl group; (iv) —R7, wherein R7 is a halogen; (v) -alkyl; (vi) —C(═O)R3, wherein R3 is H or hydrocarbyl; (vii) —C≡CR9, wherein R9 is H or hydrocarbyl; (viii) —OC(═O)NR10R11 wherein R10 and R11 are independently selected from H and hydrocarbyl; (ix), (x), (xi), (xii) and (xiii) are formulae wherein when R3 is -alkyl, R4 is present as a hydrocarbon group, when R3 is —NO2R4 is present and/or R1 is present as a sulphamate group, and when R3 is —C(═O)R3R4 is present and R1 is present as a sulphamate group.
摘要翻译:本发明提供了包含甾族环系统和选自-OH,氨基磺酸盐基团,膦酸盐基团,硫代膦酸盐基团,磺酸盐基团或磺酰胺基团中的任何一个的任选基团R1的化合物; 其中所述甾族环系统的A环任选在位置2或4处被基团R 4取代,所述基团R 4可以是合适的取代基,其中所述甾族环系统的D环被基团 R L 3,其中L是任选的连接基团,R 3选自以下基团,或其中包含一个 的(i)-SO 2 R 5,其中R 5是H,连接到D环上的烃基或键或基团 ; (ii)-NO 2 2; (iii)-SOR 6,其中R 6是H或烃基; (iv)-R 7,其中R 7为卤素; (v) - 烷基; (vi)-C(-O)R 3,其中R 3是H或烃基; (vii)-C≡CR9,其中R 9是H或烃基; (viii)-OC(-O)NR 10 R 11,其中R 10和R 11独立地选自 由H和烃基组成; (ix),(x),(xi),(xii)和(xiii)是其中当R 3为 - 烷基时,R 4为烃, 当R 3为-NO 2 R 4存在时,和/或R 1存在作为 并且当R 3为-C(-O)R 3 3 R 4时,存在R 1和R 2 >以氨基磺酸盐基团存在。
摘要:
An aqueous syrup for use in chewing gum, particularly pellet gum, comprises, on a dry basis, greater than about 98% polyols, of which i) about 50% to about 90% is sorbitol, ii) about 3% to about 30% is maltitol, iii) about 2% to about 20% are polyols, other than sorbitol and maltitol, with a degree of polymerization (DP) of 1 or 2, and iv) less than about 20% (and perhaps less than about 12%) are polyols with a DP of 3 or greater. The syrup is made with less than about 1.0% plasticizing agent, such as glycerin or propylene glycol. The syrup contains less than 5% water. The syrup can be made by evaporating a mixture of a sorbitol solution, a maltitol syrup and one or more polyols selected from the group consisting of mannitol, xylitol, lactitol, erythritol, hydrogenated isomaltulose, and combinations thereof. Methods of using the syrup to make chewing gum, and chewing gum products containing the syrup are also provided.