摘要:
A plunger and a lever are arranged in a body and provided with engaging elements engaging the lever with the plunger. The lever is disengageable from the plunger by a shift of the lever, thus enabling a movement of the plunger relatively to the body in the proximal direction.
摘要:
A first output member is rotatable around an axis relatively to the body. A second output member is movable relatively to the body along the axis. The first output member and the second output member are rotationally coupled. A drive feature is provided to generate a rotation of the first output member. A part which is removable from and attachable to the body is provided so that the first output member is unidirectionally rotationally coupled with the drive feature when the part is attached to the body.
摘要:
A drive assembly (2) for a pen-type injector, comprising: a guiding means (40) having a first (42) and a second end (41), a drive means (20), an elongate member (30) coupled to the guiding means (40) and adapted to be driven by the drive means (20) for displacing the guiding means (40) with respect to the drive means (20), a piston member (60) displaceably disposed at the first end (42) of the guiding means (40) and an adjusting member (62) displaceably disposed at the second end (41) of the guiding means (40), wherein the drive means (20) is fixedly located with respect to the adjusting member (62), and wherein the piston member (60) and the adjusting member (62) are coupled such that the sum of the distance between the piston member (60) and the guiding means (40) and the distance between the adjusting means (62) and the guiding means (40) remains constant, and a pen-type injector with such a drive assembly.
摘要:
A drug delivery device is provided comprising a dose setting mechanism having a spindle and a cartridge holder coupled to the dose setting mechanism. The cartridge holder comprising a cartridge having a movable bung at one end of the cartridge. The cartridge holder must be rotated before a dose may set with the dose setting mechanism.
摘要:
A resettable dosing mechanism comprises a dose button and a dial grip operatively coupled to the dose button. A spindle acts on a bung of a cartridge and a driver is operatively coupled between the dose button and the spindle. During an injection of the dose, the dose button moves in an axial direction to cause the spindle to administer the dose. During resetting of the dose setting mechanism, the spindle is retracted back into the dose setting mechanism. An advantageous resetting mechanism is described.
摘要:
A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing (17) and an inner housing (5) having an external groove (30; 31). The inner housing guides a driver (7, 9) having either a blocking or locking member (11; 11′) disposed inside the driver that can lock a flexible tab (21) to an internal groove during dose delivery in the inner housing such that the driver follows the path of the groove and to advance a spindle to move a cartridge bung. A dial sleeve (3) is disposed between the outer and inner housing and is rotatably engaged with the inner housing.
摘要:
The invention relates to an impeller for growing adherent mammalian cells on microcarrier beads. In other aspects, the invention relates to methods of using the impeller and to bioreactors or cell separators comprising the impeller.
摘要:
A medicament delivery device (1) comprises a housing (15), a telescopic piston rod assembly (12) for driving a bung (20) of a medicament container (9), and a drive mechanism (17) for the telescopic piston rod assembly. The telescopic piston rod assembly (12) has an input drive (23) telescopically coupled to a plunger (55) for driving the bung (20) via an intermediate coupling. The intermediate coupling comprises first and second cylinders (45, 49) telescopically coupled to one another. The plunger (55) is telescopically coupled to one of the first and second cylinders (45, 49) and the input drive (23) is telescopically coupled to the other cylinder. A key (14) is provided for restraining rotation of the plunger (55) relative to the housing (15) so that as the drive mechanism (17) drives the input drive, the plunger, first and second members and input drive telescopically expand or retract with respect to one another.