公开(公告)号：US20110240158A1

公开(公告)日：2011-10-06

申请号：US13080537

申请日：2011-04-05

Applicant: Daniel Py

Inventor： Daniel Py

IPC: E03B1/00 ,  B23P19/00

CPC classification number: F16L41/02 ,  A61M39/18 ,  A61M39/26 ,  A61M2039/267 ,  Y10T29/49826 ,  Y10T137/0318 ,  Y10T137/87925 ,  Y10T137/87949 ,  Y10T137/87957

Abstract: An aseptic fluid connector having a first connector including a first fluid passageway for receiving a fluid therein; a first port in fluid communication with the first fluid passageway for passage of the fluid therethrough; and a first deflecting member. The first deflecting member includes a first engaging portion radially spaced relative to the first port, and a first valve movable between a closed position and an open position with movement of the first engaging portion between a non-deflected position and a deflected position, respectively. In the non-deflected position, the first valve is located in the closed position forming a fluid-tight seal between the first valve and first port and preventing the passage of fluid therethrough, and in the deflected position, the first valve is located in the open position allowing the aseptic passage of fluid through the first port.

Abstract translation: 一种无菌流体连接器，其具有包括用于在其中接收流体的第一流体通道的第一连接器; 与第一流体通道流体连通以使流体通过其中的第一端口; 和第一偏转构件。 第一偏转构件包括相对于第一端口径向间隔开的第一接合部分，以及在关闭位置和打开位置之间可移动的第一阀，其中第一接合部分分别在非偏转位置和偏转位置之间移动。 在非偏转位置，第一阀位于关闭位置，在第一阀和第一端口之间形成流体密封并防止流体通过，并且在偏转位置，第一阀位于 打开位置允许流体通过第一端口的无菌通道。

公开(公告)号：USD644322S1

公开(公告)日：2011-08-30

申请号：US29379390

申请日：2010-11-18

Applicant: Daniel Py ,  Norbert M. Assion ,  Stephanie Ferreira

Designer： Daniel Py ,  Norbert M. Assion ,  Stephanie Ferreira

公开(公告)号：US08007193B2

公开(公告)日：2011-08-30

申请号：US12710516

申请日：2010-02-23

Applicant: Daniel Py ,  Julian Chan ,  David Fellows ,  Eric E. Hartman ,  Bing He

Inventor： Daniel Py ,  Julian Chan ,  David Fellows ,  Eric E. Hartman ,  Bing He

IPC: A46B11/02

CPC classification number: B65D83/0094 ,  A45D34/04 ,  A45D2200/055 ,  A45D2200/056 ,  A61M35/003 ,  B05B11/00416 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3033 ,  B05B11/3094 ,  B65B1/04 ,  B65D83/0033 ,  G01F11/025 ,  G01F11/08

Abstract: A dispenser for dispensing a substance, such as a pharmaceutical, ophthalmic, dermatological, cosmeceutical, cosmetic or other product, has a body with a variable-volume storage chamber for storing the product. A dispensing portion of the dispenser is connected with the body and has a compression chamber in fluid communication with the storage chamber for receiving substance therefrom, and an outlet aperture coupled in fluid communication with the compression chamber. A one-way valve of the dispenser includes an axially-extending valve seat and an axially-extending flexible valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat and the seam is connectable in fluid communication with the outlet aperture to allow the passage of substance through the seam and out of the dispenser.

Abstract translation: 用于分配诸如药物，眼科，皮肤病学，药妆，化妆品或其他产品的物质的分配器具有用于存储产品的具有可变容积的储存室的主体。 分配器的分配部分与主体连接并且具有与储存室流体连通的用于从其接收物质的压缩室以及与压缩室流体连通的出口孔。 分配器的单向阀包括轴向延伸的阀座和位于阀座上的轴向延伸的柔性阀盖，并且在其间限定一个常闭的轴向延伸的接缝，形成在阀盖之间的流体密封 和阀座。 柔性阀盖可相对于阀座移动，并且接缝可与出口孔流体连通以允许物质通过接缝并从分配器中通过。

公开(公告)号：US07886937B2

公开(公告)日：2011-02-15

申请号：US12685359

申请日：2010-01-11

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65D88/54

CPC classification number: G01F11/021 ,  B05B11/3001 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3047 ,  B05B11/3074 ,  B65D47/2031 ,  B65D83/00 ,  B65D83/0033 ,  B65D83/0072 ,  G01F11/02

Abstract: A dispenser has a housing, and a variable-volume storage chamber formed within the housing and defining a substantially fluid-tight seal between the chamber and exterior of the housing for storing a substance to be dispensed. A piston is mounted within the housing, and a one-way valve is mounted within the housing and coupled in fluid communication with the variable-volume storage chamber. A compression chamber is coupled in fluid communication between the piston and one-way valve, and at least one of the piston and valve is manually depressible relative to the other between (i) a first position in which the piston is located at least partially outside of the compression chamber for permitting substance to flow from the variable-volume storage chamber into the compression chamber, and (ii) a second position in which the piston is located at least partially within the compression chamber for pressurizing substance within the compression chamber above a valve opening pressure and, in turn, dispensing substance through the one-way valve and out of the dispenser.

Abstract translation: 分配器具有壳体和形成在壳体内的可变容积的储存室，并且在壳体的室和外部之间限定基本上流体密封的密封，用于存储待分配的物质。 活塞安装在壳体内，并且单向阀安装在壳体内并且与可变容积存储室流体连通地联接。 压缩室在活塞和单向阀之间流体连通地联接，并且活塞和阀门中的至少一个在第一位置之间相对于另一个手动地相对地被压下，其中活塞位于至少部分外部 的压缩室，用于允许物质从可变容积的储存室流入压缩室，以及（ii）第二位置，其中活塞至少部分地位于压缩室内，用于将压缩室内的物质加压在压缩室的上方 打开阀门的压力，并通过单向阀分配物质并从分配器中分出物质。

公开(公告)号：US07874129B2

公开(公告)日：2011-01-25

申请号：US12371601

申请日：2009-02-14

Applicant: Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  M. Jeffrey Willey

Inventor： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  M. Jeffrey Willey

IPC: B65B3/02 ,  B65B5/02

CPC classification number: B65B3/022

Abstract: Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

Abstract translation: 用于模制和填充具有本体的装置的装置，该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件，包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。 模具包括在无菌室内的多个模具腔，其形状形成封闭件和主体，以及基本上无菌的表面，其围绕并邻近模具腔的周边延伸。 包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分，其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。 柔性屏障耦合到模具和工具，以基本上防止污染物从模制机器和工具通过。

公开(公告)号：US20100331808A1

公开(公告)日：2010-12-30

申请号：US12874744

申请日：2010-09-02

Applicant: Daniel Py ,  Norbert M. Assion ,  Julian V. Chan

Inventor： Daniel Py ,  Norbert M. Assion ,  Julian V. Chan

IPC: A61M5/31 ,  G01F11/12 ,  B67D3/00

CPC classification number: B65D51/002 ,  A45D34/04 ,  A45D2200/055 ,  A61J1/1406 ,  A61J7/0053 ,  B05B11/02 ,  B67D99/00 ,  G01F11/027

Abstract: A dispenser is provided for the delivery of controlled, metered amounts of any of numerous different substances to humans or animals, such as medicaments, pharmaceuticals, cosmetics, and food products, or to deliver materials that may react upon exposure to air, such as glue. Means are provided in the dispenser to effect controlled delivery of a pre-determined amount of the substance contained in the dispenser. A one-way valve is provided to hermetically seal the portion of the dispenser containing the substance to be dispensed.

Abstract translation: 提供分配器用于向人或动物（例如药物，药物，化妆品和食品）递送受控量的计量量的任何不同物质，或者输送在暴露于空气中可能反应的材料，例如胶 。 在分配器中提供装置以实现预定量的包含在分配器中的物质的受控输送。 提供单向阀以气密地密封包含待分配物质的分配器的部分。

公开(公告)号：USD628689S1

公开(公告)日：2010-12-07

申请号：US29346863

申请日：2009-11-06

Applicant: Daniel Py ,  Norbert M. Assion

Designer： Daniel Py ,  Norbert M. Assion

公开(公告)号：US20100280466A1

公开(公告)日：2010-11-04

申请号：US12724370

申请日：2010-03-15

Applicant: Daniel Py ,  Julian V. Chan ,  Jeffrey M. Atwood

Inventor： Daniel Py ,  Julian V. Chan ,  Jeffrey M. Atwood

IPC: A61M35/00 ,  A61F9/00

CPC classification number: B05B11/007 ,  A61F9/0008 ,  A61M11/007 ,  A61M15/08 ,  A61M35/003 ,  A61M2210/0612 ,  B05B11/00412 ,  B05B11/00416 ,  B05B11/0056 ,  B05B11/0072 ,  B05B11/3004 ,  B05B11/3056 ,  B05B11/307 ,  B05B11/3074 ,  B05B11/3077

Abstract: An ophthalmic delivery device includes a body defining a fluid reservoir and a pump in fluid communication with the reservoir. The delivery device also includes a nozzle that includes a dosage chamber for holding a dosage of fluid, a valve seat, and a valve cover. The valve cover extends about the valve seat and forms an interface therebetween and the valve seat includes an outlet aperture. The interface is in fluid communication with the outlet aperture and the dosage chamber, and at least part of the valve cover is movable between (i) a closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The valve seat and the valve cover are dimensioned to dispense the dosage of fluid through the interface at a velocity of equal to or less than 6 meters per second.

Abstract translation: 眼科输送装置包括限定流体储存器的主体和与储存器流体连通的泵。 输送装置还包括喷嘴，该喷嘴包括用于保持流体用量的剂量室，阀座和阀盖。 阀盖围绕阀座延伸并且在它们之间形成界面，并且阀座包括出口孔。 所述界面与所述出口孔和所述剂量室流体连通，并且所述阀盖的至少一部分可在（i）与所述阀盖接合所述阀座的关闭位置之间移动以关闭所述界面并形成流体密封 密封在其间，和（ii）打开位置，其中阀盖的至少一部分响应于流体以大于阀打开压力的压力流过出口孔而与阀座间隔开，以允许加压流体在其间通过 。 阀座和阀盖的尺寸设计为以等于或小于6米/秒的速度通过界面分配流体的剂量。

公开(公告)号：US20100276035A1

公开(公告)日：2010-11-04

申请号：US12837329

申请日：2010-07-15

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B3/04

CPC classification number: A61M5/3129 ,  A61J1/2041 ,  A61J1/2044 ,  A61J1/2055 ,  A61J1/2093 ,  A61M5/1782 ,  A61M5/284 ,  A61M2005/3123

Abstract: A syringe and a reconstitution syringe are provided for the delivery of controlled doses of any of numerous different sterile substances, such as vaccines, medicaments, pharmaceutical preparations, cosmetics, and food products. A plunger of the syringe defines a resealable stopper frictionally and slidably received within a hollow syringe body for dispensing the medicament or other substance through a dispensing tip of the syringe upon movement of the plunger. The resealable stopper defines a heat-sealable portion to allow the stopper to be penetrated by a needle or other filling device to fill the syringe with a medicament or other substance, and in turn allow the hole remaining upon withdrawal of the needle to be heat sealed by transmission of laser energy thereon. A reconstitution syringe defines within a syringe body plural compartments, wherein each compartment stores a respective component of a multi-component medicament or other preparation.

Abstract translation: 提供注射器和重组注射器用于递送受控剂量的许多不同的无菌物质，例如疫苗，药物，药物制剂，化妆品和食品中的任何一种。 注射器的柱塞限定了摩擦并可滑动地容纳在中空注射器主体内的可再密封塞子，用于在柱塞移动时通过注射器的分配尖端分配药物或其它物质。 可重新密封的止动件限定了可热封部分，以允许止动器被针或其他填充装置穿透，以用药物或其它物质填充注射器，并且进而允许在针头被热封时提供剩余的孔 通过在其上传输激光能量。 重建注射器在注射器主体内限定多个隔室，其中每个隔室存储多组分药物或其它制剂的相应组分。

公开(公告)号：USD625200S1

公开(公告)日：2010-10-12

申请号：US29352148

申请日：2009-12-17

Applicant: Daniel Py ,  Julian V. Chan

Designer： Daniel Py ,  Julian V. Chan