公开(公告)号：US20100280466A1

公开(公告)日：2010-11-04

申请号：US12724370

申请日：2010-03-15

申请人： Daniel Py ,  Julian V. Chan ,  Jeffrey M. Atwood

发明人： Daniel Py ,  Julian V. Chan ,  Jeffrey M. Atwood

IPC分类号： A61M35/00 ,  A61F9/00

CPC分类号： B05B11/007 ,  A61F9/0008 ,  A61M11/007 ,  A61M15/08 ,  A61M35/003 ,  A61M2210/0612 ,  B05B11/00412 ,  B05B11/00416 ,  B05B11/0056 ,  B05B11/0072 ,  B05B11/3004 ,  B05B11/3056 ,  B05B11/307 ,  B05B11/3074 ,  B05B11/3077

摘要： An ophthalmic delivery device includes a body defining a fluid reservoir and a pump in fluid communication with the reservoir. The delivery device also includes a nozzle that includes a dosage chamber for holding a dosage of fluid, a valve seat, and a valve cover. The valve cover extends about the valve seat and forms an interface therebetween and the valve seat includes an outlet aperture. The interface is in fluid communication with the outlet aperture and the dosage chamber, and at least part of the valve cover is movable between (i) a closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The valve seat and the valve cover are dimensioned to dispense the dosage of fluid through the interface at a velocity of equal to or less than 6 meters per second.

摘要翻译： 眼科输送装置包括限定流体储存器的主体和与储存器流体连通的泵。 输送装置还包括喷嘴，该喷嘴包括用于保持流体用量的剂量室，阀座和阀盖。 阀盖围绕阀座延伸并且在它们之间形成界面，并且阀座包括出口孔。 所述界面与所述出口孔和所述剂量室流体连通，并且所述阀盖的至少一部分可在（i）与所述阀盖接合所述阀座的关闭位置之间移动以关闭所述界面并形成流体密封 密封在其间，和（ii）打开位置，其中阀盖的至少一部分响应于流体以大于阀打开压力的压力流过出口孔而与阀座间隔开，以允许加压流体在其间通过 。 阀座和阀盖的尺寸设计为以等于或小于6米/秒的速度通过界面分配流体的剂量。

公开(公告)号：US07678089B2

公开(公告)日：2010-03-16

申请号：US10990164

申请日：2004-11-15

申请人： Daniel Py ,  Julian V. Chan ,  Jeffrey M. Atwood

发明人： Daniel Py ,  Julian V. Chan ,  Jeffrey M. Atwood

IPC分类号： A61H33/04 ,  A61M35/00 ,  B67D5/42 ,  G01F11/00

CPC分类号： B05B11/007 ,  A61F9/0008 ,  A61M11/007 ,  A61M15/08 ,  A61M35/003 ,  A61M2210/0612 ,  B05B11/00412 ,  B05B11/00416 ,  B05B11/0056 ,  B05B11/0072 ,  B05B11/3004 ,  B05B11/3056 ,  B05B11/307 ,  B05B11/3074 ,  B05B11/3077

摘要： An ophthalmic delivery device includes a body defining a fluid reservoir and a pump in fluid communication with the reservoir. The delivery device also includes a nozzle that includes a dosage chamber for holding a dosage of fluid, a valve seat, and a valve cover. The valve cover extends about the valve seat and forms an interface therebetween and the valve seat includes an outlet aperture. The interface is in fluid communication with the outlet aperture and the dosage chamber, and at least part of the valve cover is movable between (i) a closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The valve seat and the valve cover are dimensioned to dispense the dosage of fluid through the interface at a velocity of equal to or less than 6 meters per second.

摘要翻译： 眼科输送装置包括限定流体储存器的主体和与储存器流体连通的泵。 输送装置还包括喷嘴，该喷嘴包括用于保持一定量的流体的剂量室，阀座和阀盖。 阀盖围绕阀座延伸并且在它们之间形成界面，并且阀座包括出口孔。 所述界面与所述出口孔和所述剂量室流体连通，并且所述阀盖的至少一部分可在（i）与所述阀盖接合所述阀座的关闭位置之间移动以关闭所述界面并形成流体密封 密封在其间，和（ii）打开位置，其中阀盖的至少一部分响应于流体以大于阀打开压力的压力流过出口孔而与阀座间隔开，以允许加压流体在其间通过 。 阀座和阀盖的尺寸设计为以等于或小于6米/秒的速度通过界面分配流体的剂量。

公开(公告)号：US20140246462A1

公开(公告)日：2014-09-04

申请号：US14101981

申请日：2013-12-10

申请人： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

发明人： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

IPC分类号： B65D37/00

CPC分类号： B67D1/108 ,  B05B11/00444 ,  B65B39/004 ,  B65D51/002 ,  B65D51/1616 ,  B67D1/0004 ,  B67D1/0007 ,  B67D1/0009 ,  B67D1/0082 ,  B67D1/0801 ,  B67D1/10 ,  B67D1/1279 ,  B67D3/0067 ,  B67D3/04 ,  B67D2001/0827 ,  F04B53/1037

摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

摘要翻译： 提供了一种柔性袋和阀组件，用于无菌存储物质，从其中分配多部分储存物质，并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。 柔性袋和阀组件可接收在相对刚性的壳体内，并且适于与泵协作，用于泵送物质的离散部分并且通过单向阀从其分配物质。 组件包括柔性袋，其中限定有相对于环境大气密封的可变容积存储室，用于将物质的多个部分无菌存储。 组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。

公开(公告)号：US08602259B2

公开(公告)日：2013-12-10

申请号：US13362532

申请日：2012-01-31

申请人： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

发明人： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

IPC分类号： B67D7/14

CPC分类号： B67D1/108 ,  B05B11/00444 ,  B65B39/004 ,  B65D51/002 ,  B65D51/1616 ,  B67D1/0004 ,  B67D1/0007 ,  B67D1/0009 ,  B67D1/0082 ,  B67D1/0801 ,  B67D1/10 ,  B67D1/1279 ,  B67D3/0067 ,  B67D3/04 ,  B67D2001/0827 ,  F04B53/1037

摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

公开(公告)号：US20130175298A1

公开(公告)日：2013-07-11

申请号：US13572310

申请日：2012-08-10

申请人： Daniel Py ,  Julian V. Chan ,  Giovanni Rodriguez

发明人： Daniel Py ,  Julian V. Chan ,  Giovanni Rodriguez

IPC分类号： B65D35/28

CPC分类号： B65D35/28 ,  A45D34/04 ,  A45D2034/007 ,  A45D2200/055

摘要： A dispenser for dispensing a substance, such as a liquid lipstick or other cosmetic, pharmaceutical or cosmeceutical product, has a body with a variable-volume storage chamber for storing the product. A dispensing portion is connected with the body and a one-way valve for dispensing amounts of product therethrough. The dispensing portion defines a compression chamber in fluid communication with the storage chamber for receiving product therefrom, and an outlet aperture coupled in fluid communication with the compression chamber. The one-way valve has a valve seat, and a visco-elastic valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat, and the seam is connectable in fluid communication with the outlet aperture to allow the passage of product through the seam and out of the dispenser. An actuator is drivingly connected to the compression chamber for pressurizing product within the compression chamber and dispensing an amount of product within the compression chamber.

摘要翻译： 用于分配物质的分配器，例如液体口红或其它化妆品，药​​物或药妆产品，具有具有用于存储产品的可变容积储存室的主体。 分配部分与主体连接，单向阀用于分配产品的数量。 分配部分限定与储存室流体连通的压缩室，用于从其中接收产品，以及与压缩室流体连通的出口孔。 单向阀具有阀座和安置在阀座上的粘弹性阀盖，并且在其间形成常闭的轴向延伸的接缝，形成在阀盖和阀座之间的流体密封。 柔性阀盖可相对于阀座移动，并且接缝可与出口孔流体连通以允许产品通过接缝并从分配器中通过。 致动器驱动地连接到压缩室，用于对压缩室内的产品进行加压，并且在压缩室内分配一定数量的产品。

公开(公告)号：US07845517B2

公开(公告)日：2010-12-07

申请号：US11008887

申请日：2004-12-09

申请人： Daniel Py ,  Julian V. Chan ,  Giovanni Rodriguez

发明人： Daniel Py ,  Julian V. Chan ,  Giovanni Rodriguez

IPC分类号： B67D1/00

CPC分类号： B65D51/226 ,  B65D47/2075

摘要： A device for storing and dispensing a substance includes a container having a body defining therein a storage chamber for receiving and storing the substance. The container includes a head located at one end of the body and a first passageway that is in fluid communication with the storage chamber of the body and defines a flow path therebetween. The container also includes a pierceable wall located on an opposite side of the passageway relative to the storage chamber, and a first connecting portion for connecting another component thereto. The device also includes a one-way valve assembly that includes a valve body including a body base defining a second passageway and at least one piercing portion engageable with the pierceable wall of the container. The valve assembly includes a second connecting portion that is connectable to the first connecting portion of the container for fixedly securing the valve assembly to the container when the valve assembly and container are located in the second position. The valve assembly includes a valve seat and at least one flow aperture extending through the valve body adjacent to the valve seat and in fluid communication with the second passageway for receiving the substance from the storage chamber therethrough.

摘要翻译： 用于存储和分配物质的装置包括具有在其中限定有用于接收和存储物质的储存室的主体的容器。 容器包括位于主体一端的头部和与主体的储存室流体连通并限定其间的流路的第一通道。 容器还包括位于通道相对于储存室的相对侧上的可穿透壁，以及用于将另一部件连接到其上的第一连接部分。 该装置还包括单向阀组件，该单向阀组件包括阀体，该阀体包括限定第二通道的主体基座和与容器的可刺穿壁可接合的至少一个穿孔部分。 阀组件包括可连接到容器的第一连接部分的第二连接部分，用于当阀组件和容器位于第二位置时将阀组件固定地固定到容器。 阀组件包括阀座和至少一个流动孔，其延伸穿过与阀座相邻的阀体，并与第二通道流体连通，用于通过其从储存室接收物质。

公开(公告)号：USD608659S1

公开(公告)日：2010-01-26

申请号：US29318782

申请日：2008-05-28

申请人： Daniel Py ,  Julian V. Chan ,  Gladys Luz Valencia

设计人： Daniel Py ,  Julian V. Chan ,  Gladys Luz Valencia

公开(公告)号：USD579786S1

公开(公告)日：2008-11-04

申请号：US29245373

申请日：2005-12-22

申请人： Daniel Py ,  Julian V. Chan ,  Gladys Luz Valencia

设计人： Daniel Py ,  Julian V. Chan ,  Gladys Luz Valencia

公开(公告)号：US07328729B2

公开(公告)日：2008-02-12

申请号：US11349873

申请日：2006-02-08

申请人： Daniel Py ,  Julian V. Chan

发明人： Daniel Py ,  Julian V. Chan

IPC分类号： B65B1/04

CPC分类号： B65D83/62 ,  A61J1/00 ,  A61J1/1443 ,  B65B3/30 ,  B65B31/044 ,  B65D83/425

摘要： A dispenser for holding multiple doses of fluids or other substances, and for dispensing the substances, has a variable volume storage chamber. A filling valve is coupled in fluid communication with the storage chamber and defines (1) a normally closed, fluid-tight position hermetically sealing the storage chamber from the ambient atmosphere, and (2) an open position allowing the passage of fluid through the valve both to evacuate the storage chamber and to introduce fluid through the valve to fill the storage chamber. A dispensing valve is coupled in fluid communication with the storage chamber and defines (1) a normally closed, fluid-tight position preventing the passage of fluid out of the dispenser, and (2) an open position for dispensing fluid therethrough. The sealed, empty dispenser is sterilized, such as by applying gamma radiation thereto. Then, the sterilized, sealed, empty dispenser is filled with fluid by engaging the filling valve with a filling member and introducing fluid from the filling member through the filling valve and into the storage chamber. The fluid in the storage chamber is dispensed through the dispensing valve.

摘要翻译： 用于保持多个剂量的流体或其他物质并用于分配物质的分配器具有可变容积的储存室。 填充阀与储存室流体连通地联接并且限定（1）将储存室与环境大气密封的常闭密封的流体密封位置，和（2）允许流体通过阀门的打开位置 两者都抽真空储存室并引入流体通过阀门填充储存室。 分配阀与存储室流体连通地联接并且限定（1）常闭的流体密封位置，防止流体从分配器通过，以及（2）用于分配流体的打开位置。 密封的空分配器被灭菌，例如通过对其施加γ射线。 然后，通过将填充阀与填充构件接合并将填充构件的流体通过填充阀引入到储存室中，灭菌的密封的空分配器充满流体。 存储室中的流体通过分配阀分配。

公开(公告)号：USD521639S1

公开(公告)日：2006-05-23

申请号：US29193804

申请日：2003-11-14

申请人： Daniel Py ,  Julian V. Chan

设计人： Daniel Py ,  Julian V. Chan