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公开(公告)号：US20110238149A1
公开(公告)日：2011-09-29
申请号：US13051558
申请日：2011-03-18
申请人： Liliana Atanasoska , Angela Kostrewa , Matthew Cambronne , James Q. Feng , Rajesh Radhakrishnan
发明人： Liliana Atanasoska , Angela Kostrewa , Matthew Cambronne , James Q. Feng , Rajesh Radhakrishnan
CPC分类号： A61L31/022 , A61L31/06 , A61L31/088 , A61L31/10 , A61L31/148 , A61L31/16 , Y10T29/49982 , C08L67/04
摘要： Endoprostheses and methods of making endoprostheses are disclosed. For example, endoprostheses are described that include an endoprosthesis body, a biodegradable metallic tie layer, and a polymer coating about the endoprosthesis body. The biodegradable tie layer and the polymer coating can have a high peel strength from the body.
摘要翻译： 公布内裤假体和内用假体的方法。 例如，描述了内括约肌假体，生物可降解的金属粘结层和围绕内置假体的聚合物涂层。 可生物降解的粘结层和聚合物涂层可以具有来自身体的高剥离强度。
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92.发明授权Organic-inorganic hybrid particle material and polymer compositions containing same 有权有机 - 无机杂化颗粒材料和含有它们的聚合物组合物公开(公告)号：US08008395B2
公开(公告)日：2011-08-30
申请号：US11235743
申请日：2005-09-27
CPC分类号： A61L27/427 , A61L31/124 , C08G77/458 , Y10T428/2982
摘要： Particulate materials useful as fillers, reinforcing agents, radioopacifiers, or impact modifiers. The particulate material has an average particle size range of about 10,000 nm or less and comprises an organic-inorganic hybrid material that has a ceramic material network having organic polymer segments distributed throughout the ceramic network. The ceramic network may be prepared by a sol-gel technique. The particulate material may be compounded in thermoplastic polymer compositions useful in a variety of applications such as preparation of medical device components.
摘要翻译： 可用作填料，增强剂，放射线光刻胶或抗冲改性剂的颗粒材料。 颗粒材料具有约10,000nm或更小的平均粒度范围，并且包含具有分布在整个陶瓷网络中的有机聚合物链段的陶瓷材料网络的有机 - 无机混合材料。 陶瓷网络可以通过溶胶 - 凝胶技术制备。 颗粒材料可以在可用于各种应用的热塑性聚合物组合物中复合，例如制备医疗装置组分。
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公开(公告)号：US20090281613A1
公开(公告)日：2009-11-12
申请号：US12117932
申请日：2008-05-09
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2230/0013 , A61F2240/001 , A61F2250/0031 , A61L31/022 , A61L31/10 , A61L31/148 , A61L2400/12 , A61L2400/18 , C08L67/04
摘要： An endoprosthesis includes a body defining a flow passage therethrough. The body is capable of maintaining patency in a blood vessel and includes iron or an alloy thereof. The body has a nano-structured surface comprising iron oxide in which the individual nano-structures have a height to thickness aspect ratio of at least 5:1.
摘要翻译： 内假体包括限定穿过其中的流动通道的主体。 身体能够在血管中保持通畅并且包括铁或其合金。 身体具有包含氧化铁的纳米结构化表面，其中各个纳米结构的高度与厚度纵横比至少为5:1。
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公开(公告)号：US20070149690A1
公开(公告)日：2007-06-28
申请号：US11317614
申请日：2005-12-23
IPC分类号： C08K3/40
CPC分类号： A61L31/128 , A61L27/446 , A61L29/126 , C08K9/02 , C08K9/04 , C08K2201/013 , C08L53/00
摘要： Reinforced copolymers formed from a functionalized copolymer that undergoes a reactive extrusion process with an inorganic component to form the reinforced copolymer. The functionalized copolymer in the form of a block and/or graft copolymer includes hard segments and soft segments, where the soft segments are covalently bonded with a coupling agent either before or after copolymerization with the hard segments. The reinforced copolymer of the present disclosure can be suitable for use as a biomaterial and/or in medical devices.
摘要翻译： 由官能化共聚物形成的增强共聚物，其经历与无机组分的反应性挤出方法以形成增强共聚物。 块状和/或接枝共聚物形式的官能化共聚物包括硬链段和软链段，其中软链段在与硬链段共聚合之前或之后与偶联剂共价键合。 本公开的增强共聚物可适用于生物材料和/或医疗装置。
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公开(公告)号：US20070048348A1
公开(公告)日：2007-03-01
申请号：US11213177
申请日：2005-08-26
申请人： Liliana Atanasoska , Robert Warner , Scott Schewe
发明人： Liliana Atanasoska , Robert Warner , Scott Schewe
IPC分类号： A61F2/06
CPC分类号： A61L29/14 , A61L29/08 , A61L29/126 , C08L101/04
摘要： A medical device having at least one composite region thereon formed of composite material comprising a polymer and a fluorinated sol-gel derived ceramic. The composite material is useful as a coating material for imparting a low coefficient of friction to a substrate.
摘要翻译： 一种具有至少一个复合材料区域的医疗装置，由复合材料形成，包括聚合物和氟化溶胶 - 凝胶衍生的陶瓷。 复合材料可用作赋予基材低摩擦系数的涂料。
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公开(公告)号：US20060230476A1
公开(公告)日：2006-10-12
申请号：US11094638
申请日：2005-03-30
申请人： Liliana Atanasoska , Scott Schewe , Robert Warner
发明人： Liliana Atanasoska , Scott Schewe , Robert Warner
CPC分类号： A61L29/12 , A61L31/12 , C23C18/1216 , C23C18/1254
摘要： Implantable or insertable medical devices that have one or more composite regions. These composite regions include polymer and sol-gel derived ceramic. The polymer and sol-gel ceramic may form bi-continuous phases or separate polymeric and sol-gel derived ceramic phases.
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公开(公告)号：US08895099B2
公开(公告)日：2014-11-25
申请号：US13051558
申请日：2011-03-18
申请人： Liliana Atanasoska , Angela Kostrewa , Matthew Cambronne , James Q. Feng , Rajesh Radhakrishnan
发明人： Liliana Atanasoska , Angela Kostrewa , Matthew Cambronne , James Q. Feng , Rajesh Radhakrishnan
IPC分类号： B05D3/00 , A61L33/00 , A61F2/06 , A61L31/16 , A61L31/06 , A61L31/14 , A61L31/08 , A61L31/10 , A61L31/02
CPC分类号： A61L31/022 , A61L31/06 , A61L31/088 , A61L31/10 , A61L31/148 , A61L31/16 , Y10T29/49982 , C08L67/04
摘要： Endoprostheses and methods of making endoprostheses are disclosed. For example, endoprostheses are described that include an endoprosthesis body, a biodegradable metallic tie layer, and a polymer coating about the endoprosthesis body. The biodegradable tie layer and the polymer coating can have a high peel strength from the body.
摘要翻译： 公布内裤假体和内用假体的方法。 例如，描述了假体内括约肌体，生物可降解金属粘结层和围绕内置假体的聚合物涂层。 可生物降解的粘结层和聚合物涂层可以具有来自身体的高剥离强度。
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98.发明授权Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments 有权用于治疗剂递送的医疗装置，其聚合物区域包含具有两个软链段和均匀长度的硬链段的共聚物公开(公告)号：US08440214B2
公开(公告)日：2013-05-14
申请号：US11344053
申请日：2006-01-31
申请人： Michael Arney , Liliana Atanasoska , Robert Warner
发明人： Michael Arney , Liliana Atanasoska , Robert Warner
CPC分类号： A61L27/34 , A61F2250/0067 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/604
摘要： Implantable or insertable medical devices are described, which include one or more polymeric regions and one or more therapeutic agents. The polymeric regions, which regulate the release of one or more therapeutic agent from the medical device, contain copolymer molecules, each of which includes one or more soft segments and one or more uniform hard segments (e.g., polyamide segments that do not vary in length from molecule to molecule, among others).
摘要翻译： 描述了可植入或可插入的医疗装置，其包括一个或多个聚合物区域和一种或多种治疗剂。 调节一种或多种治疗剂从医疗装置释放的聚合物区域含有共聚物分子，每一种共聚物分子包括一个或多个软链段和一个或多个均匀的硬链段（例如，长度不变的聚酰胺链段 从分子到分子等）。
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公开(公告)号：US08231980B2
公开(公告)日：2012-07-31
申请号：US12630250
申请日：2009-12-03
申请人： Liliana Atanasoska , Pankaj Gupta , Charles Deng
发明人： Liliana Atanasoska , Pankaj Gupta , Charles Deng
CPC分类号： B32B9/00 , A61F2/82 , A61L31/028 , A61L31/088 , C23C14/08
摘要： A medical implant includes iridium oxide. The iridium oxide has a plurality of Ir—O σ bonds and a plurality of Ir═O π bonds. The iridium oxide has a ratio of the Ir—O σ bonds to the Ir═O π bonds that is greater than 1.3.
摘要翻译： 医疗植入物包括氧化铱。 氧化铱具有多个Ir-O＆amp; 债券和多个Ir = O＆pgr; 债券。 氧化铱具有Ir-O和sgr的比例; 债券到Ir=O＆pgr; 大于1.3的债券。
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公开(公告)号：US20120029613A1
公开(公告)日：2012-02-02
申请号：US13156980
申请日：2011-06-09
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2210/0004 , A61F2210/0076 , A61F2310/00017 , A61F2310/00065 , A61F2310/00107
摘要： An endoprosthesis includes a composite. The composite includes a matrix comprising a bioerodible iron or a bioerodible iron alloy and particles within the matrix. The particles include palladium, manganese oxide, a transition metal oxide, or a combination thereof.
摘要翻译： 内假体包括复合材料。 该复合材料包括一种包含生物可腐蚀铁或生物可腐蚀铁合金的基质和基质内的颗粒。 颗粒包括钯，氧化锰，过渡金属氧化物或其组合。
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