Imidazonaphthyridine derivatives
    91.
    发明授权
    Imidazonaphthyridine derivatives 失效
    咪唑并萘啶衍生物

    公开(公告)号:US5468756A

    公开(公告)日:1995-11-21

    申请号:US241631

    申请日:1994-05-12

    CPC分类号: C07D471/14

    摘要: Disclosed are imidazonaphthyridine derivatives represented by formula (I) ##STR1## wherein: R.sup.1 represents lower alkyl or substituted or unsubstituted aryl; andX--Y--Z represents ##STR2## wherein R.sup.2 represents hydrogen, lower alkyl, alkenyl, aralkenyl, or --C (R.sup.5)H--(CH.sub.2).sub.n --R.sup.4 (wherein R.sup.4 represents substituted or unsubstituted aryl, substituted or unsubstituted pyridyl, substituted or unsubstituted furyl, hydroxy-substituted lower alkyl, lower alkanoyloxy, morpholino, lower alkanoyl, carboxy, lower alkoxycarbonyl, cycloalkyl, hydroxy, lower alkoxy, halogen or NR.sup.6 R.sup.7 wherein R.sup.6 and R.sup.7 independently represents hydrogen or lower alkyl; R.sup.5 represents hydrogen, lower alkyl, or phenyl; and n represents an integer of 0 to 3); and R.sup.3 represents hydrogen, mercapto, hydroxy, lower alkyl, or aryland pharmaceutically acceptable salts thereof.The compounds show a potent anti-inflammatory, anti-allergic and broncho-dilative activity.

    摘要翻译: 公开了由式(I)表示的咪唑并吡啶衍生物其中:R1表示低级烷基或取代或未取代的芳基; 并且XYZ表示其中R2表示氢,低级烷基,烯基,芳烯基或-C(R5)H-(CH2)n-R4(其中R4表示取代或未取代的芳基,取代或未取代的吡啶基,取代或未取代的呋喃基 羟基取代的低级烷基,低级烷酰氧基,吗啉代,低级烷酰基,羧基,低级烷氧基羰基,环烷基,羟基,低级烷氧基,卤素或NR6R7,其中R6和R7独立地表示氢或低级烷基; R5表示氢,低级烷基或苯基; n表示0〜3的整数)。 并且R 3表示氢,巯基,羟基,低级烷基或芳基及其药学上可接受的盐。 这些化合物显示有效的抗炎,抗过敏和支气管扩张活性。

    Xanthine derivatives
    92.
    发明授权
    Xanthine derivatives 失效
    黄嘌呤衍生物

    公开(公告)号:US5342841A

    公开(公告)日:1994-08-30

    申请号:US29069

    申请日:1993-03-10

    CPC分类号: C07D473/06

    摘要: A xanthine derivative of the formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are substituted or unsubstituted alicyclic alkyl; m1 and m2 are the same or different and represent an integer of 0 to 2; and Q represents ##STR2## (in which R.sup.3 and R.sup.4 are the same or different and are substituted or unsubstituted alicyclic alkyl) or ##STR3## (in which n is 0 or 1, and Y is a single bond or alkylene); or a pharmaceutically acceptable salt thereof is disclosed.This derivative has diuretic activity and renal protecting activity.

    摘要翻译: 式(I)的黄嘌呤衍生物:其中R1和R2相同或不同,为取代或未取代的脂环族烷基; m1和m2相同或不同,表示0〜2的整数。 和Q表示(其中R 3和R 4相同或不同,是取代或未取代的脂环族烷基)或(其中n为0或1,Y为单键或亚烷基)。 或其药学上可接受的盐。 该衍生物具有利尿活性和肾脏保护活性。

    Method and an apparatus for handling wafers
    94.
    发明授权
    Method and an apparatus for handling wafers 失效
    用于处理波形的方法和装置

    公开(公告)号:US5226758A

    公开(公告)日:1993-07-13

    申请号:US812621

    申请日:1991-12-23

    IPC分类号: H01L21/304 H01L21/00

    摘要: A semiconductor wafer handling apparatus and method for transferring a wafer, one of whose faces has been already polished, from a wafer holder, which holds the wafer with the wafer's polished face facing downward, to a wafer cassette submerged in water contained in a water tank; the apparatus includes a wafer receive assembly and a water tank and the wafer receive assembly has a flat surface and is adapted to swing between an up-facing position at which the flat surface faces upward and a down-facing position at which the flat surface faces downward, and the wafer receive assembly is provided with ejection nozzles which eject water with a force sufficient to keep the wafer floating, and the water tank contains a wafer cassette to receive the wafer, and is capable of forcing the wafer which is left to sink in the water to enter the wafer cassette; whereas the method comprises: dropping the wafer from the wafer holder with the polished face facing downward onto a thin water layer formed over the wafer receive assembly; swinging the wafer receive assembly together with the wafer through an angle of about 180.degree. so that the wafer is turned upside down and brought in the water tank, whereupon the wafer sinks through the water with the polished face facing upward; and forcing the wafer to enter the wafer cassette.

    Multifilament type plastic optical fiber endoscope
    96.
    发明授权
    Multifilament type plastic optical fiber endoscope 失效
    多层塑料光纤内窥镜

    公开(公告)号:US5127079A

    公开(公告)日:1992-06-30

    申请号:US658869

    申请日:1991-02-22

    摘要: An endoscope comprising as an image-transmitting member a multifilament type plastic optical fiber in which 50 to 20,000 islands having a core-sheath structure, a core diameter of 2 to 70 .mu.m and a circular or substantially circular section are arranged in a zigzag-stacked or square-stacked structure in the sea having a circular or substantially circular section, so that the lamination structure of the entire cores has a substantially circular shape in the section of the image-transmitting portion, wherein the same positional relationship of the ends of light-transmitting paths arranged in the section of the optical fiber is maintained on both the ends of the optical fiber, the periphery of the section of the image-transmitting portion of the optical fiber has a circular or substantially circular shape, and an object lens is attached to one end of the image-transmitting member and an image-transmitting light-receiving member is arranged on the other end of the image-transmitting member.

    Optical fiber coupler and a fabrication method for the same
    98.
    发明授权
    Optical fiber coupler and a fabrication method for the same 失效
    光纤耦合器及其制造方法

    公开(公告)号:US5058979A

    公开(公告)日:1991-10-22

    申请号:US242469

    申请日:1990-06-21

    IPC分类号: G02B6/255 G02B6/28 G02B6/34

    摘要: The present invention provides a wide wavelength range optical fiber coupler that to the greatest extent possible, allows optical coupling which is wavelength independent, and thus demonstrates a constant coupling ratio over a wide range of wavelengths. By causing various irregularities to be formed in the fused-elongated region of an optical fiber coupler, thereby leading to the generation of additional modes in addition to the fundamental modes, while at the same time causing multiple mode coupling in which the above mentioned additional modes participate in the coupling of the fundamental modes, it is possible to selectively control the coupling strength at determined wavelengths and thereby achieve optical coupling which is largely wavelength independent and thus demonstrates a relatively constant coupling ratio over a wide range of wavelengths. Furthermore, by causing the strength of coupling between the cores of each component optical fiber to vary along the length of the longitudinal axis of each component optical fiber, it is possible to decrease the degree of sinusoidal variation in the wavelength dependance characteristics of each component optical fiber, thereby making it possible to further achieve optical coupling which is wavelength independent and thus considerably constant over a wide range of wavelengths.

    Method for producing rubber modified thermoplastic resins
    99.
    发明授权
    Method for producing rubber modified thermoplastic resins 失效
    橡胶改性热塑性树脂的制造方法

    公开(公告)号:US4992510A

    公开(公告)日:1991-02-12

    申请号:US394720

    申请日:1989-08-16

    IPC分类号: C08J3/00 C08L51/04

    CPC分类号: C08J3/005 C08L51/04

    摘要: Disclosed is method for producing a rubber modified thermoplastic reins which comprises carrying out all or a part of the following setps (I) - (VI):(I) a step of mixing the following (A), (B), (C) and thermoplastic resin (2):(A) a latex of graft rubber polymer (1),(B) an organic agent which is capable of dissolving thermoplastic resin (2) and has a solubility in water of 5% by weight or less at a temperature at which (A), (B), (C) and thermoplastic resin (2) are mixed, amount of the organic agent being 10-600% by weight of polymer (4) which is the sum of graft rubber polymer (1) and thermoplastic resin (2) and(C) a water soluble agent capable of coagulating latex (A), amount of this agent being 10% by weight or less of graft rubber polymer (1),(II) a step of separating and removing aqueous phase from a two-phase mixture obtained in the mixing step (I),(III) a step of mixing the mixture from which the aqueous phase has been removed at step (II) and the whole or a part of thermoplastic resin (3),(IV) a step of removing a part or the whole of organic agent (B) and remaining water from the mixture obtained at step (III) by a thermal means,(V) a step of mixing the remainder of thermoplastic resin (3) in case a part of thermoplastic resin (3) has been mixed at step (III), and(VI) a step of removing the remainder of organic agent (B) in case only a part of organic agent (B) has been removed at step (IV).

    Process for producing phosphinylamino acid derivatives
    100.
    发明授权
    Process for producing phosphinylamino acid derivatives 失效
    制备氧膦基氨基酸衍生物的方法

    公开(公告)号:US4906764A

    公开(公告)日:1990-03-06

    申请号:US193775

    申请日:1988-05-13

    CPC分类号: C07F9/301 C07F9/3211

    摘要: A process for producing a phosphinylamino acid derivative of the formula: ##STR1## wherein R.sup.1 is a lower alkyl group, R.sup.2 is a hydrogen atom, a lower alkyl group, a halo-lower alkyl group or a substituted or unsubstituted phenyl group, and R.sup.3 is a substituted or unsubstituted alkyl group or a substituted or unsubstituted phenyl group, which comprises reacting a compound of the formula: ##STR2## wherein R.sup.1 and R.sup.2 are as defined above, and/or a compound of the formula: ##STR3## wherein R.sup.1 and R.sup.2 are as defined above, with a compound of the formula:R.sup.3 CONH.sub.2 (IV)wherein R.sup.3 is as defined above, carbon monoxide and hydrogen in the presence of a catalyst containing a metal of group VIII of the Periodic Table.