公开(公告)号：US11260212B2

公开(公告)日：2022-03-01

申请号：US16277411

申请日：2019-02-15

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Daniel Glozman ,  Gad Lubinsky

IPC: A61M1/12 ,  A61M60/205 ,  A61M60/50 ,  A61M60/135 ,  A61M60/148 ,  A61M60/414 ,  A61M60/818 ,  A61M60/857

Abstract: Apparatus and methods are described including a tube configured to traverse a subject's aortic valve. A frame is disposed within a portion of the tube, and an impeller is disposed inside the tube such that, when the impeller and the tube are deployed inside the subject, a gap between an outer edge of the impeller and an inner surface of the tube is less than 1 mm. The impeller rotates such as to pump blood from the left ventricle to the aorta, and is stabilized with respect to the tube, such that, during rotation of the impeller, the gap between the outer edge of the impeller and the inner surface of the tube is maintained. The impeller includes at least one impeller blade defined by a helical elongate element, and a film of material supported by the helical elongate element. Other applications are also described.

公开(公告)号：US11039915B2

公开(公告)日：2021-06-22

申请号：US16335786

申请日：2017-09-28

Applicant: MAGENTA MEDICAL LTD.

Inventor： Yosi Tuval ,  Ehud Schwammenthal ,  Daniel Glozman ,  Gad Lubinsky

IPC: A61F2/07 ,  A61F2/06 ,  A61B5/0215 ,  A61B5/00 ,  A61F2/48

Abstract: Apparatus and methods are described including a tube (20) that defines a flared downstream portion (30) that diverges toward a downstream end (32) of the tube, and a flared upstream portion (26) that diverges toward an upstream end (28) of the tube, such that a central portion (34) of the tube is narrower than at the ends of the tube. The tube defines a plurality of lateral openings (36). A support frame (24) supports the tube within a subject's vena cava, such that the downstream portion is sealed with respect to the wall of the vena cava downstream of junctions of the vena cava with all of the subject's renal veins, and the upstream portion is sealed with respect to the inner wall of the vena cava upstream of junctions of the vena cava with all of the subject's renal veins. Other applications are also described.

公开(公告)号：US20210178147A1

公开(公告)日：2021-06-17

申请号：US17182482

申请日：2021-02-23

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M60/422 ,  A61B5/0215 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00 ,  A61B5/283 ,  A61M60/40 ,  A61M60/50 ,  A61M60/135 ,  A61M60/148 ,  A61M60/205 ,  A61M60/414 ,  A61M60/419 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896

Abstract: A blood pump is described that includes an impeller having proximal and distal bushings, at least one helical elongate element, a spring that is disposed inside of the helical elongate element and along an axis around which the helical elongate element winds, and a film of material supported between the helical elongate element and the spring. A frame is disposed around the impeller. A flexible elongate element extends radially from the spring to the helical elongate element, and maintains the helical elongate element within a given distance from the spring, to thereby maintain a gap between an outer edge of a blade of the impeller and an inner surface of the frame, during rotation of the impeller. Other applications are also described.

公开(公告)号：US20210178146A1

公开(公告)日：2021-06-17

申请号：US17180041

申请日：2021-02-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M60/422 ,  A61B5/0215 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00 ,  A61B5/283 ,  A61M60/40 ,  A61M60/50 ,  A61M60/135 ,  A61M60/148 ,  A61M60/205 ,  A61M60/414 ,  A61M60/419 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft, an impeller disposed on the axial shaft, a frame disposed around the impeller, and a motor disposed outside a subject's body, and configured to drive the impeller to pump blood from a distal end of the impeller to a proximal end of the impeller. A drive cable extends from outside the subject's body to the axial shaft, and is configured to impart rotational motion from the motor to the impeller by rotating. The drive cable is held in a preloaded state with respect to the frame, such that initiation of pumping of blood by rotation of the impeller does not cause the drive cable to axially elongate. Other applications are also described.

公开(公告)号：US20210170159A1

公开(公告)日：2021-06-10

申请号：US17173944

申请日：2021-02-11

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/829 ,  A61M60/896 ,  A61M60/818 ,  A61M60/419 ,  A61M60/857 ,  A61M60/422

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller, a frame disposed around the impeller, and a distal-tip portion disposed distally with respect to the frame. A duckbill valve is disposed entirely within a distal most 10 mm of the distal-tip portion. The duckbill valve defines a wide inlet and a narrow tip that defines a slit therethrough. The duckbill valve is proximally facing, such that the wide inlet faces a distal end of the distal-tip portion and such that the narrow tip faces away from the distal end of distal-tip portion. Other applications are also described.

公开(公告)号：US20210077676A1

公开(公告)日：2021-03-18

申请号：US16952327

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a left ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject and to pump blood from the left ventricle to an aorta of the subject, by rotating. A frame is disposed around the impeller. A tube is configured to traverse an aortic valve of the subject, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube extends to a distal end of the frame and defines one or more lateral blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. Other applications are also described.

公开(公告)号：US20210069395A1

公开(公告)日：2021-03-11

申请号：US16952444

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A braided element is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.

公开(公告)号：US20210069394A1

公开(公告)日：2021-03-11

申请号：US16952389

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A mesh is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.

公开(公告)号：US20210038792A1

公开(公告)日：2021-02-11

申请号：US17077769

申请日：2020-10-22

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle. A frame is disposed around the impeller, the frame defining generally-cylindrical central portion, and a proximal conical portion that widens from a proximal end of the frame to a proximal end of the generally-cylindrical central portion. A motor drives the impeller to pump blood from the left ventricle to the subject's aorta, by rotation of the impeller. The impeller is configured to be disposed at least partially within the proximal conical portion of the frame during at least some of a time during which the impeller rotates. Other applications are also described.

公开(公告)号：US20210038790A1

公开(公告)日：2021-02-11

申请号：US17069064

申请日：2020-10-13

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus comprising and methods are described including a blood pump that includes an axial shaft, and an impeller disposed on the axial shaft. The impeller is configured to pump blood of the subject by rotating. The impeller and the axial shaft are configured to undergo axial back-and-forth motion during operation of the impeller. A distal tip element is disposed at a distal end of the blood pump. The distal tip element defines an axial-shaft-receiving tube, configured to receive at least a portion of the axial shaft during forward motion of the axial shaft. The distal tip element additionally defines an atraumatic distal tip portion disposed distally of the axial-shaft-receiving tube. Other applications are also described.