公开(公告)号：US20140135613A1

公开(公告)日：2014-05-15

申请号：US14061143

申请日：2013-10-23

申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES

发明人： Taiga YAMAYA ,  Takayuki OBATA

IPC分类号： G01R33/48

CPC分类号： G01R33/481 ,  G01R33/307 ,  G01R33/56375 ,  G01T1/1603

摘要： A PET/MRI device includes an MRI device that has a measurement port, a PET detector that can be inserted into the measurement port, and a mechanism that can slide the PET detector into and out of the MRI measurement port. Thereby, the PET/MRI device allows MRI measurement during PET measurement.

摘要翻译： PET / MRI装置包括具有测量端口的MRI装置，可以插入测量端口的PET检测器，以及可以将PET检测器滑入和流出MRI测量端口的机构。 因此，PET / MRI装置允许在PET测量期间进行MRI测量。

公开(公告)号：US20140061483A1

公开(公告)日：2014-03-06

申请号：US13846443

申请日：2013-03-18

申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES

发明人： Eiji YOSHIDA ,  Taiga YAMAYA

IPC分类号： G01T1/164

CPC分类号： G01T1/164 ,  G01T1/1647 ,  G01T1/2985

摘要： In a coincidence determination of a PET device, the PET device uses a scintillator of radioactive isotope containing background noise due to intrinsic radioactivity as a radiation detector. The PET device counts a pair of annihilation radiations that is assumed to occur from a same nuclide. The annihilation radiations are detected within a predetermined coincidence time window by a plurality of radiation detectors. The method includes determining a coincidence with a wide energy window that allows detecting the background noise due to intrinsic radioactivity as multiple coincidences; removing the multiple coincidences; and using an energy window narrower than the wide energy window to limit a coincidence event to a coincidence event in a photopeak from a positron nuclide only.

摘要翻译： 在PET装置的重合判定中，PET装置使用由于内在放射性而含有背景噪声的放射性同位素的闪烁体作为放射线检测器。 PET装置计算出假定从同一个核素发生的一对湮灭辐射。 通过多个辐射检测器在预定的重合时间窗内检测湮灭辐射。 该方法包括确定与宽能量窗口的一致性，其允许将由于固有放射性的背景噪声检测为多重重合; 消除多重巧合; 并且使用比宽能窗口窄的能量窗口，以将符合事件限制在仅来自正电子核素的光峰中的重合事件。

公开(公告)号：US08581196B2

公开(公告)日：2013-11-12

申请号：US12996443

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

发明人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

IPC分类号： G01T1/161

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/4266 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.

摘要翻译： 在通过用X射线，γ射线或粒子束照射受影响区域进行的用于检测通过放射治疗癌症的放射线照射产生的湮灭辐射的光束监测中，提供了检测器移位型组合放射治疗/ PET装置 一种开放的PET装置，包括多个可移动的多环检测器环; 以及能够通过检测器环之间的辐射束照射的放射线照射装置。 该装置改变检测器环的位置，通过检测器环之间的辐射束进行照射，然后执行辐射测量。

公开(公告)号：US08552408B2

公开(公告)日：2013-10-08

申请号：US13577741

申请日：2011-02-07

申请人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10

CPC分类号： A61N5/1043 ,  A61N5/1071 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/025

摘要： Provided is a particle beam irradiation apparatus capable of highly reliable measurement of a dose of each beam and capable of highly sensitive measurement of a leakage dose caused by momentary beam emission. The particle beam irradiation apparatus according to the present invention includes: an emission control portion that controls emission and termination of a particle beam; a control portion that sequentially changes an irradiation position of the particle beam relative to an affected area; first and second dosimeters that measure dose rates of the particle beam directed to the affected area; and an abnormality determination portion that accumulates the dose rates output from the first and second dosimeters for each of predetermined determination periods to calculate first and second sectional dose measurement values and that performs second abnormality determination of determining that there is an abnormality and outputs an interlock signal for terminating the emission of the particle beam in at least one of a case in which the first sectional dose measurement value exceeds a predetermined first reference range and a case in which the second sectional dose measurement value exceeds a predetermined second reference range.

摘要翻译： 提供一种能够高度可靠地测量每个光束的剂量并且能够高度敏感地测量由瞬时光束发射引起的泄漏剂量的粒子束照射装置。 根据本发明的粒子束照射装置包括：发射控制部分，其控制粒子束的发射和终止; 控制部，其依次改变所述粒子束相对于受影响区域的照射位置; 测量指向受影响区域的粒子束的剂量率的第一和第二剂量计; 以及异常判定部，其对于每个规定的判定期间累积从第一和第二剂量计输出的剂量率，以计算第一和第二截面剂量测量值，并且执行确定存在异常的第二异常判定并输出互锁信号 用于在第一部分剂量测量值超过预定的第一参考范围的情况和第二部分剂量测量值超过预定的第二参考范围的情况中的至少一个中终止粒子束的发射。

公开(公告)号：US20130234710A1

公开(公告)日：2013-09-12

申请号：US13873706

申请日：2013-04-30

申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES ,  TOSHIBA MEDICAL SYSTEMS CORPORATION

发明人： Iwao KANNO ,  Takayuki OBATA ,  Taiga YAMAYA ,  Kazuya OKAMOTO ,  Takuzo TAKAYAMA ,  Hitoshi YAMAGATA

IPC分类号： G01R33/422

CPC分类号： G01R33/422 ,  A61B5/0035 ,  A61B5/055 ,  A61B6/037 ,  A61B6/4417 ,  A61B6/5235 ,  A61B6/5247 ,  G01R33/481 ,  G01T1/1603

摘要： In a PET (Positron Emission Tomography)-MRI (Magnetic Resonance Imaging) apparatus of an embodiment, a transmitting radio frequency coil applies a radio frequency magnetic field on a subject placed in a static magnetic field. A detector is formed in a ring shape, disposed on a side adjacent to an outer circumference of the transmitting radio frequency coil, includes at least two PET detectors disposed with a space therebetween in an axial direction of a bore so as to interpose the magnetic field center of the static magnetic field therebetween, and detects gamma rays emitted from positron emitting radionuclides injected into the subject. Radio frequency shields are each formed in an approximately cylindrical shape, disposed between the transmitting radio frequency coil and the detector, and shield the radio frequency magnetic field generated by the transmitting radio frequency coil.

摘要翻译： 在实施例的PET（正电子发射断层摄影）-MRI（磁共振成像）装置中，发射射频线圈对放置在静磁场中的被摄体施加射频磁场。 检测器形成为环形，设置在与发射射频线圈的外周相邻的一侧，包括至少两个在孔的轴向方向上设置有空间的PET检测器，以便将磁场 并且检测从注射到被检体内的正电子发射放射性核素发出的γ射线。 射频屏蔽各自形成为大致圆筒形，设置在发射射频线圈和检测器之间，并屏蔽由发射射频线圈产生的射频磁场。

公开(公告)号：US08466418B2

公开(公告)日：2013-06-18

申请号：US12999212

申请日：2009-06-25

申请人： Hidehito Nakamura

发明人： Hidehito Nakamura

IPC分类号： G01T1/164 ,  G01T1/166

CPC分类号： G01T1/1644 ,  A61B6/037 ,  G01T1/2985

摘要： A gamma ray detector for detecting a gamma ray emitted from a target of measurement includes: an organic scintillator for detecting Compton electrons resulting from a gamma ray emitted from the target of measurement; an inorganic scintillator for detecting a Compton gamma ray; and photodetector modules for detecting light generation in the corresponding scintillators. Light generation signals from the organic and inorganic scintillators are synchronously measured, and a detection window of a gamma ray is generated. Thus, an inexpensive radiation diagnostic device of an ultra-high S/N ratio and low cost is provided.

摘要翻译： 一种用于检测从测量目标发射的伽马射线的伽马射线检测器包括：用于检测从测量目标发射的伽马射线产生的康普顿电子的有机闪烁体; 用于检测康普顿伽马射线的无机闪烁体; 以及用于检测相应的闪烁体中的光产生的光电检测器模块。 来自有机和无机闪烁体的发光信号被同步测量，产生伽马射线的检测窗口。 因此，提供了超高S / N比和低成本的便宜的辐射诊断装置。

公开(公告)号：US20130037722A1

公开(公告)日：2013-02-14

申请号：US13638745

申请日：2010-03-30

申请人： Taiga Yamaya ,  Eiji Yoshida

发明人： Taiga Yamaya ,  Eiji Yoshida

IPC分类号： G01T1/164

CPC分类号： A61B6/037 ,  A61B6/5205

摘要： In imaging on the basis of list mode data of a list of radioactive count data detected by a nuclear medicine imaging apparatus for measuring radiation in a pulse mode, the processing from the measurement to imaging of radiation is accelerated substantially to the real time level by selecting the number of count data to be used for online imaging computations on the basis of the counting rate of radiation.

摘要翻译： 在基于由用于测量脉冲模式中的辐射的核医学成像装置检测的放射性计数数据的列表的列表模式数据的成像中，从测量到辐射成像的处理被大幅加速到实时水平，通过选择 基于辐射计数率用于在线成像计算的计数数据的数量。

公开(公告)号：US20130030287A1

公开(公告)日：2013-01-31

申请号：US13639008

申请日：2010-04-08

申请人： Taiga Yamaya

发明人： Taiga Yamaya

IPC分类号： A61B6/00 ,  G01T1/164

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： Provided are a proximity imaging type PET apparatus and a system which include a part-specific PET scanner disposed in proximity to a specific part of a measurement target and a whole-body PET scanner which is capable of radiographing the whole body of the measurement target, the PET apparatus and system being capable of bringing PET detectors into close proximity to the specific part of the measurement target so as to ensure higher sensitivity and imaging a wide field of view.

摘要翻译： 提供了一种接近成像型PET装置和包括设置在测量对象的特定部分附近的部分特定PET扫描仪和能够对测量对象的全身进行射线照相的全身PET扫描仪的系统， PET装置和系统能够将PET检测器带到测量对象的特定部分附近，以确保较高的灵敏度和成像的宽视场。

公开(公告)号：US20130020489A1

公开(公告)日：2013-01-24

申请号：US13639346

申请日：2010-04-06

申请人： Eiji Yoshida ,  Taiga Yamaya

发明人： Eiji Yoshida ,  Taiga Yamaya

IPC分类号： G01T1/164

CPC分类号： G01T1/2985

摘要： For coincidence determination, a PET device that regards and counts a pair of annihilation radiations detected within a predetermined time as occurring from the same nuclide changes a coincidence time width according to a maximum detection time difference. This prevents the inclusion of extra noise data for improved image quality.

摘要翻译： 为了一致判定，在从同一个核素发生的预定时间内检测到的一对湮灭辐射的PET计数器根据最大检测时间差改变一致时间宽度。 这样可以防止包含额外的噪音数据来提高图像质量。

公开(公告)号：US20120305796A1

公开(公告)日：2012-12-06

申请号：US13577509

申请日：2011-02-07

申请人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10 ,  G21K5/04

CPC分类号： A61N5/10 ,  A61N5/1043 ,  A61N5/1075 ,  A61N2005/1074 ,  A61N2005/1087 ,  G01T1/2935

摘要： Provided is a particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan with a simple configuration, while reducing degradation of a particle beam shape. The particle beam irradiation apparatus according to the present invention includes: a beam generation portion that generates a particle beam; a beam emission control portion that controls emission of the particle beam; a beam scanning portion that two-dimensionally scans the particle beam; a sensor portion including a plurality of first linear electrodes arranged in parallel in a first direction and a plurality of second linear electrodes arranged in parallel in a second direction orthogonal to the first direction; a beam shape calculation portion that calculates a center of gravity of the particle beam from a first signal output from each of the first linear electrodes and a second signal output from each of the second linear electrodes and that obtains a two-dimensional beam shape of the particle beam around the center of gravity; a storage portion that accumulates and stores the two-dimensional beam shapes; and a display portion that displays the two-dimensional beam shapes as a two-dimensional distribution of a dose.

摘要翻译： 提供一种粒子束照射装置，其能够以简单的构造在扫描期间测量和显示剂量二维分布，同时减少粒子束形状的劣化。 根据本发明的粒子束照射装置包括：产生粒子束的光束产生部; 控制粒子束发射的光束发射控制部分; 二维地扫描粒子束的光束扫描部; 传感器部分，包括沿第一方向平行布置的多个第一线性电极和沿与第一方向正交的第二方向平行设置的多个第二线性电极; 光束形状计算部分，其根据从每个第一线性电极输出的第一信号和从每个第二线性电极输出的第二信号计算粒子束的重心，并且获得二维波束形状 颗粒束围绕重心; 存储部，其积存并存储二维光束形状; 以及显示部，其将二维光束形状显示为剂量的二维分布。