公开(公告)号：US08487282B2

公开(公告)日：2013-07-16

申请号：US13577509

申请日：2011-02-07

申请人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10

CPC分类号： A61N5/10 ,  A61N5/1043 ,  A61N5/1075 ,  A61N2005/1074 ,  A61N2005/1087 ,  G01T1/2935

摘要： A particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan while reducing degradation of a particle beam shape, including a particle beam generation portion; a particle beam emission control portion; a two-dimensional beam scanning portion; a sensor portion including first linear electrodes arranged in parallel in a first direction and second linear electrodes arranged in parallel in a second direction orthogonal to the first direction; a beam shape calculation portion that calculates a center of gravity of the particle beam from outputs of each the first linear and second linear electrodes and that obtains a two-dimensional beam shape of the particle beam around the center of gravity; a storage portion that accumulates and stores the two-dimensional beam shapes; and a display portion that displays the two-dimensional beam shapes as a two-dimensional distribution of a dose.

摘要翻译： 一种粒子束照射装置，其能够在扫描期间测量并显示剂量二维分布，同时减少包括粒子束产生部分在内的粒子束形状的退化; 粒子束发射控制部分; 二维光束扫描部分; 传感器部分包括沿第一方向平行布置的第一线性电极和沿与第一方向正交的第二方向平行布置的第二线性电极; 束形状计算部，其从所述第一线状电极和所述第二线状电极的输出计算所述粒子束的重心，并且获得所述粒子束围绕所述重心的二维束形状; 存储部，其积存并存储二维光束形状; 以及显示部，其将二维光束形状显示为剂量的二维分布。

公开(公告)号：US20120305790A1

公开(公告)日：2012-12-06

申请号：US13577741

申请日：2011-02-07

申请人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10

CPC分类号： A61N5/1043 ,  A61N5/1071 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/025

摘要： Provided is a particle beam irradiation apparatus capable of highly reliable measurement of a dose of each beam and capable of highly sensitive measurement of a leakage dose caused by momentary beam emission. The particle beam irradiation apparatus according to the present invention includes: an emission control portion that controls emission and termination of a particle beam; a control portion that sequentially changes an irradiation position of the particle beam relative to an affected area; first and second dosimeters that measure dose rates of the particle beam directed to the affected area; and an abnormality determination portion that accumulates the dose rates output from the first and second dosimeters for each of predetermined determination periods to calculate first and second sectional dose measurement values and that performs second abnormality determination of determining that there is an abnormality and outputs an interlock signal for terminating the emission of the particle beam in at least one of a case in which the first sectional dose measurement value exceeds a predetermined first reference range and a case in which the second sectional dose measurement value exceeds a predetermined second reference range.

摘要翻译： 提供一种能够高度可靠地测量每个光束的剂量并且能够高度敏感地测量由瞬时光束发射引起的泄漏剂量的粒子束照射装置。 根据本发明的粒子束照射装置包括：发射控制部分，其控制粒子束的发射和终止; 控制部，其依次改变所述粒子束相对于受影响区域的照射位置; 测量指向受影响区域的粒子束的剂量率的第一和第二剂量计; 以及异常判定部，其对于每个规定的判定期间累积从第一和第二剂量计输出的剂量率，以计算第一和第二截面剂量测量值，并且执行确定存在异常的第二异常判定并输出互锁信号 用于在第一部分剂量测量值超过预定的第一参考范围的情况和第二部分剂量测量值超过预定的第二参考范围的情况中的至少一个中终止粒子束的发射。

公开(公告)号：US08552408B2

公开(公告)日：2013-10-08

申请号：US13577741

申请日：2011-02-07

申请人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10

CPC分类号： A61N5/1043 ,  A61N5/1071 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/025

摘要： Provided is a particle beam irradiation apparatus capable of highly reliable measurement of a dose of each beam and capable of highly sensitive measurement of a leakage dose caused by momentary beam emission. The particle beam irradiation apparatus according to the present invention includes: an emission control portion that controls emission and termination of a particle beam; a control portion that sequentially changes an irradiation position of the particle beam relative to an affected area; first and second dosimeters that measure dose rates of the particle beam directed to the affected area; and an abnormality determination portion that accumulates the dose rates output from the first and second dosimeters for each of predetermined determination periods to calculate first and second sectional dose measurement values and that performs second abnormality determination of determining that there is an abnormality and outputs an interlock signal for terminating the emission of the particle beam in at least one of a case in which the first sectional dose measurement value exceeds a predetermined first reference range and a case in which the second sectional dose measurement value exceeds a predetermined second reference range.

摘要翻译： 提供一种能够高度可靠地测量每个光束的剂量并且能够高度敏感地测量由瞬时光束发射引起的泄漏剂量的粒子束照射装置。 根据本发明的粒子束照射装置包括：发射控制部分，其控制粒子束的发射和终止; 控制部，其依次改变所述粒子束相对于受影响区域的照射位置; 测量指向受影响区域的粒子束的剂量率的第一和第二剂量计; 以及异常判定部，其对于每个规定的判定期间累积从第一和第二剂量计输出的剂量率，以计算第一和第二截面剂量测量值，并且执行确定存在异常的第二异常判定并输出互锁信号 用于在第一部分剂量测量值超过预定的第一参考范围的情况和第二部分剂量测量值超过预定的第二参考范围的情况中的至少一个中终止粒子束的发射。

公开(公告)号：US20120305796A1

公开(公告)日：2012-12-06

申请号：US13577509

申请日：2011-02-07

申请人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10 ,  G21K5/04

CPC分类号： A61N5/10 ,  A61N5/1043 ,  A61N5/1075 ,  A61N2005/1074 ,  A61N2005/1087 ,  G01T1/2935

摘要： Provided is a particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan with a simple configuration, while reducing degradation of a particle beam shape. The particle beam irradiation apparatus according to the present invention includes: a beam generation portion that generates a particle beam; a beam emission control portion that controls emission of the particle beam; a beam scanning portion that two-dimensionally scans the particle beam; a sensor portion including a plurality of first linear electrodes arranged in parallel in a first direction and a plurality of second linear electrodes arranged in parallel in a second direction orthogonal to the first direction; a beam shape calculation portion that calculates a center of gravity of the particle beam from a first signal output from each of the first linear electrodes and a second signal output from each of the second linear electrodes and that obtains a two-dimensional beam shape of the particle beam around the center of gravity; a storage portion that accumulates and stores the two-dimensional beam shapes; and a display portion that displays the two-dimensional beam shapes as a two-dimensional distribution of a dose.

摘要翻译： 提供一种粒子束照射装置，其能够以简单的构造在扫描期间测量和显示剂量二维分布，同时减少粒子束形状的劣化。 根据本发明的粒子束照射装置包括：产生粒子束的光束产生部; 控制粒子束发射的光束发射控制部分; 二维地扫描粒子束的光束扫描部; 传感器部分，包括沿第一方向平行布置的多个第一线性电极和沿与第一方向正交的第二方向平行设置的多个第二线性电极; 光束形状计算部分，其根据从每个第一线性电极输出的第一信号和从每个第二线性电极输出的第二信号计算粒子束的重心，并且获得二维波束形状 颗粒束围绕重心; 存储部，其积存并存储二维光束形状; 以及显示部，其将二维光束形状显示为剂量的二维分布。

公开(公告)号：US08581196B2

公开(公告)日：2013-11-12

申请号：US12996443

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

发明人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

IPC分类号： G01T1/161

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/4266 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.

摘要翻译： 在通过用X射线，γ射线或粒子束照射受影响区域进行的用于检测通过放射治疗癌症的放射线照射产生的湮灭辐射的光束监测中，提供了检测器移位型组合放射治疗/ PET装置 一种开放的PET装置，包括多个可移动的多环检测器环; 以及能够通过检测器环之间的辐射束照射的放射线照射装置。 该装置改变检测器环的位置，通过检测器环之间的辐射束进行照射，然后执行辐射测量。

公开(公告)号：US20110084211A1

公开(公告)日：2011-04-14

申请号：US12996443

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

发明人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

IPC分类号： G01T1/161 ,  A61N5/10

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/4266 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.

摘要翻译： 在通过用X射线，γ射线或粒子束照射受影响区域进行的用于检测通过放射治疗癌症的放射线照射产生的湮灭辐射的光束监测中，提供了检测器移位型组合放射治疗/ PET装置 一种开放的PET装置，包括多个可移动的多环检测器环; 以及能够通过检测器环之间的辐射束照射的放射线照射装置。 该装置改变检测器环的位置，通过检测器环之间的辐射束进行照射，然后执行辐射测量。

公开(公告)号：US08193512B2

公开(公告)日：2012-06-05

申请号：US11922204

申请日：2005-10-31

申请人： Takuji Furukawa ,  Kouji Noda

发明人： Takuji Furukawa ,  Kouji Noda

IPC分类号： G21K5/10

CPC分类号： H05H7/12 ,  A61N5/1043 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K1/093 ,  G21K5/04

摘要： An irradiation field forming device for forming an irradiation field when a specimen is irradiated with a charged particle beam generated by an accelerator, the irradiation field forming device includes: a range shifter arranged on a beam axis of the charged particle beam for regulating an irradiation depth of the charged particle beam; and two or more than two converging electromagnets arranged in the downstream of the range shifter for regulating a beam diameter of the charged particle beam which is enlarged by the range shifter to a constant value.

摘要翻译： 一种照射场形成装置，用于在用加速器产生的带电粒子束照射样本时形成照射场，所述照射场形成装置包括：距离移位器，布置在所述带电粒子束的束轴上，用于调节照射深度 的带电粒子束; 以及布置在量程移位器下游的两个或多于两个会聚电磁体，用于调节由范围移位器放大的带电粒子束的光束直径为恒定值。

公开(公告)号：US07919759B2

公开(公告)日：2011-04-05

申请号：US11792940

申请日：2005-10-31

申请人： Takuji Furukawa ,  Kouji Noda

发明人： Takuji Furukawa ,  Kouji Noda

IPC分类号： H01J1/50

CPC分类号： A61N5/10 ,  A61N5/1081 ,  A61N2005/1087 ,  G21K5/04 ,  H05H7/04

摘要： A charged particle beam 2 which enters a final bending electromagnet 7 after traveling through quadrupole electromagnets 4, 5, 6 travels through the final bending electromagnet 7 in an arc shape path by increasing or decreasing a bending magnetic field generated in the final bending electromagnet 7, with a pre-determined period for example and is scanned in an X-direction. The charged particle beam 2 scanned in the X-direction is scanned in a Y-direction while traveling through a Y-direction Wobbler electromagnet 8. Consequently, the charged particle beam 2 is scanned in the X-direction and the Y-direction, and the target 9 is irradiated with the charged particle beam 2 so that a round field is drawn, for example.

摘要翻译： 在通过四极电磁体4,5,6行进之后进入最终弯曲电磁体7的带电粒子束2通过增加或减少最终弯曲电磁体7中产生的弯曲磁场而以弧形轨迹行进通过最终弯曲电磁体7， 以预定的时间段为例，并沿X方向进行扫描。 沿X方向扫描的带电粒子束2在Y方向摆动电磁体8行进时沿Y方向扫描。因此，带电粒子束2沿X方向和Y方向扫描， 例如，用带电粒子束2照射靶9以使得圆场被绘制。

公开(公告)号：US20100213384A1

公开(公告)日：2010-08-26

申请号：US11922204

申请日：2005-10-31

申请人： Takuji Furukawa ,  Kouji Noda

发明人： Takuji Furukawa ,  Kouji Noda

IPC分类号： H01J37/141 ,  H01J1/50

CPC分类号： H05H7/12 ,  A61N5/1043 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K1/093 ,  G21K5/04

摘要： An irradiation field forming device for forming an irradiation field when a specimen is irradiated with a charged particle beam generated by an accelerator, the irradiation field forming device includes: a range shifter arranged on a beam axis of the charged particle beam for regulating an irradiation depth of the charged particle beam; and two or more than two converging electromagnets arranged in the downstream of the range shifter for regulating a beam diameter of the charged particle beam which is enlarged by the range shifter to a constant value.

摘要翻译： 一种照射场形成装置，用于在用加速器产生的带电粒子束照射样本时形成照射场，所述照射场形成装置包括：距离移位器，布置在所述带电粒子束的束轴上，用于调节照射深度 的带电粒子束; 以及布置在量程移位器下游的两个或多于两个会聚电磁体，用于调节由范围移位器放大的带电粒子束的光束直径为恒定值。

公开(公告)号：US20080006776A1

公开(公告)日：2008-01-10

申请号：US11792940

申请日：2005-10-31

申请人： Takuji Furukawa ,  Kouji Noda

发明人： Takuji Furukawa ,  Kouji Noda

IPC分类号： G21K1/093

CPC分类号： A61N5/10 ,  A61N5/1081 ,  A61N2005/1087 ,  G21K5/04 ,  H05H7/04

摘要： A charged particle beam 2 which enters a final bending electromagnet 7 after traveling through quadrupole electromagnets 4, 5, 6 travels through the final bending electromagnet 7 in an arc shape path by increasing or decreasing a bending magnetic field generated in the final bending electromagnet 7, with a pre-determined period for example and is scanned in an X-direction. The charged particle beam 2 scanned in the X-direction is scanned in a Y-direction while traveling through a Y-direction Wobbler electromagnet 8. Consequently, the charged particle beam 2 is scanned in the X-direction and the Y-direction, and the target 9 is irradiated with the charged particle beam 2 so that a round field is drawn, for example.

摘要翻译： 在通过四极电磁体4,5,6行进之后进入最终弯曲电磁体7的带电粒子束2通过增加或减少最终弯曲电磁体7中产生的弯曲磁场而以弧形轨迹行进通过最终弯曲电磁体7， 以预定的时间段为例，并沿X方向进行扫描。 沿X方向扫描的带电粒子束2在Y方向摆动电磁体8行进的同时沿Y方向扫描。 因此，在X方向和Y方向上扫描带电粒子束2，并且用带电粒子束2照射靶9，使得例如绘制圆场。