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    Deep Rapid Class Augmentation
    112.
    发明申请
    Deep Rapid Class Augmentation 有权

    公开(公告)号：US20210073637A1

    公开(公告)日：2021-03-11

    申请号：US17083969

    申请日：2020-10-29

    Applicant: Leidos, Inc.

    Inventor： Hanna Elizabeth Witzgall

    IPC: G06N3/08 ,  G06F16/55 ,  G06N3/04

    Abstract: Deep RCA uses a modified recursive least squares (RLS) optimization method and a novel null-class vector that together allow the algorithm to remember prior classes as it learns the new class. Deep RCA only has to be trained on the new class data which results in a significant improvement in training speed and almost no memory requirements to achieve the goal of near, real-time class augmentation for deep neural networks.

    Portable Fluidic Platform For Rapid Cell-Free Production of Protein Biologics
    114.
    发明申请
    Portable Fluidic Platform For Rapid Cell-Free Production of Protein Biologics 审中-公开

    公开(公告)号：US20200277643A1

    公开(公告)日：2020-09-03

    申请号：US16846025

    申请日：2020-04-10

    Applicant: Leidos, Inc.

    Inventor： John Dresios ,  Richard Holmes Griffey ,  Challise J. Sullivan ,  Erik D. Pendleton ,  Henri M. Sasmor ,  William L. Hicks ,  Eric M. Amendt

    IPC: C12P21/06 ,  C12N1/06

    Abstract: A portable fluidic platform for rapid and flexible end-to-end production of recombinant protein biologics includes a bioreactor system hosting stable and robust cell-free translation systems that is fluidically integrated with modular protein separation functionalities (e.g., size exclusion, ion exchange or affinity chromatography systems) for purification of the cell-free expressed product and which are configurable for process-specific isolation of different proteins, as well as for formulation. The bioreactor utilizes lysates from engineered eukaryotic (e.g., yeast) or prokaryotic (e.g., bacterial) strains that contain factors for protein folding and posttranslational modifications. Combination of various purification modules on the same fluidic platform allows flexibility of re-routing for purification of different proteins depending on specific target requirements. Protein synthesis and purification modules are integrated into self-contained disposable fluidic cartridge that eliminates cross-contamination between runs. The platform allows for flexible production of protein biologics within 24 hours (from DNA to purified product).

    Network managed antivirus appliance
    115.
    发明授权
    Network managed antivirus appliance 有权

    公开(公告)号：US10318734B2

    公开(公告)日：2019-06-11

    申请号：US14528360

    申请日：2014-10-30

    Applicant: Leidos, Inc.

    Inventor： Alan G. Young ,  Paul L. Bartruff ,  Eric E. Brown ,  Michael P. Miley

    IPC: G06F21/56 ,  H04L29/06 ,  G06F21/55

    Abstract: Data can be scanned using a network managed appliance. The network managed appliance may integrate commercial hardware elements connected through a basic or simplified operating system environment expressly developed for the appliance, thus being more malware resistant and less vulnerable to attacks from the scanned data or other sources. The network managed appliance may be a self-contained apparatus with an integrated chassis, designed and configured as “single-purpose” device. Such appliances may be connected to an appliance management network including central management servers in communication with appliances in remote locations. The central management servers may ensure that scanning software and the definitions lists for each of the appliances are current and match an enterprise-approved configuration. In addition, an antivirus appliance may facilitate creation and management of user rights assignments for those files.

    Reactive self-indicating absorbent materials, methods, and systems
    119.
    发明授权
    Reactive self-indicating absorbent materials, methods, and systems 有权

    公开(公告)号：US10201800B2

    公开(公告)日：2019-02-12

    申请号：US15155738

    申请日：2016-05-16

    Applicant: Leidos, Inc.

    Inventor： Thomas Grant Glover

    IPC: B01J20/06 ,  B01D46/00 ,  B01J20/28 ,  G01N33/543 ,  G01N27/72 ,  G01N27/403

    Abstract: The present disclosure relates, according to some embodiments, reactive self-indicating adsorbent materials, methods, and systems. A system may comprise, for example, a reactive self-indicating adsorbent material, wherein the reactive self-indicating adsorbent material comprises at least one super paramagnetic particle and a semi permeable support, wherein the at least one super paramagnetic particle is configured such that at least one magnetic property of the at least one super paramagnetic particle changes upon contact with an adsorbate; and/or at least one detector configured and arranged to detect the at least one magnetic property. In some embodiments, a method for assessing the performance and/or remaining life of an adsorbent material may comprise (a) contacting a fluid comprising an adsorbate with the adsorbent material under conditions that permit the adsorbate to contact the at least one super paramagnetic particle, wherein a change in a magnetic property of the at least one super paramagnetic particle occurs upon contact with the adsorbate; (b) detecting the magnetic property of the at least one super paramagnetic particle; and/or (c) comparing the detected magnetic property to a reference to produce an assessment of the performance and/or remaining life of the adsorbent material.

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