公开(公告)号：US20210023373A1

公开(公告)日：2021-01-28

申请号：US16520052

申请日：2019-07-23

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Daran DeShazo ,  Steven Boor ,  Gavin L. Rade

IPC: A61N1/36 ,  A61N1/378

Abstract: An implantable medical device (IMD) includes an adjustable capacitive voltage multiplier (CVM) that is responsive to diagnostic circuitry configured to provide control signals within a single stimulation current pulse for adjusting the voltage output applied to an electrode of the IMD's lead system. A control counter is coupled to the diagnostic circuitry for incrementing or decrementing an N-bit counter output signal operative to reconfigure a charge pump arrangement of the CVM so as to facilitate an adjusted voltage output.

公开(公告)号：US20200324110A1

公开(公告)日：2020-10-15

申请号：US16915073

申请日：2020-06-29

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Jeffrey T. Mitchell

IPC: A61N1/05 ,  A61N1/36

Abstract: Systems and methods for deploying a paddle neurostimulation lead within a patient. A delivery tool includes a delivery tube including a first linear segment, a second linear segment, and an arcuate segment coupled between the first and second linear segments, the second linear segment defining an elongated opening. The delivery tool further includes a stylet positioned within an interior of the delivery tube, and a handle coupled to the delivery tube and including a stylet actuation mechanism, the stylet actuation mechanism configured to selectively advance and retract the stylet between a deployed position and a retracted position, wherein the stylet extends across the elongated opening in the deployed position to engage an engagement member of the paddle neurostimulation lead.

公开(公告)号：US20200246099A1

公开(公告)日：2020-08-06

申请号：US16265674

申请日：2019-02-01

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Robert E. Jones ,  Galen L. Smith

IPC: A61B90/11 ,  A61B90/50

Abstract: A trajectory guiding apparatus and one or more methods associated therewith for facilitating precision-guided alignment and implantation of a DBS therapy device in a patient. A base plate and base frame combination provides a platform for a dual-stage slider (DSS) assembly comprising a bottom stage slider (BSS) table and a top stage slider (TSS) table that each have suitably sized apertures or orifices therethrough for allowing the passage of and securely holding an instrumentation column (IC) assembly whose translational movement (i.e., sideways or forward and/or backward directions along a translational plane) and pivotal/rotational movement (i.e., around a perpendicular axis orthogonal to the translational plane and extending through a pivot or fulcrum) are independently controlled by respective slide actuators in order to properly align the IC assembly to a desired trajectory.

公开(公告)号：US20200155851A1

公开(公告)日：2020-05-21

申请号：US16195502

申请日：2018-11-19

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Steven Boor ,  Daran DeShazo

IPC: A61N1/36 ,  A61N1/05

Abstract: A Kelvin connection scheme, apparatus and method for effectuating residual voltage measurements with respect to one or more electrodes of a lead system associated with an implantable medical device (IMD). In one example implementation, terminals of at least one DC blocking stimulation capacitor or at least one AC-coupling sense capacitor associated with at least one inactive electrode of the lead system are used as one Kelvin connection terminal of a measurement circuit path whereas a counter Kelvin connection terminal with respect to a selection of at least one active electrode is effectuated across the electrode/tissue interface using either at least one DC blocking stimulation capacitor or at least one AC-coupling sense capacitor provided therewith.

公开(公告)号：US20200147389A1

公开(公告)日：2020-05-14

申请号：US16189746

申请日：2018-11-13

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Steven Boor ,  Daran DeShazo

IPC: A61N1/36 ,  A61N1/378

Abstract: An apparatus and method for providing split stimulation currents in a pulse generator. In one embodiment, a current regulator of the pulse generator includes a digitally-programmable analog voltage generator coupled to a first input of an error amplifier that receives a second input controlled by a programmable resistor network configured to control a programmable total stimulation current output. A plurality of current splitting switches are operative to split the programmable total stimulation current output into a corresponding plurality of split current segments, which may be individually mapped to a selected set of lead electrodes across one or more implantable leads associated with the pulse generator.

公开(公告)号：US20190126032A1

公开(公告)日：2019-05-02

申请号：US16164675

申请日：2018-10-18

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Binith J. Cheeran ,  Jonathan P. Avedikian ,  Brittany L. Boudreau ,  Jason Pounds

IPC: A61N1/05 ,  A61N1/372 ,  G06F3/0482 ,  G16H40/40 ,  A61N1/378

Abstract: In some embodiments, a clinician programmer device for controlling a deep brain stimulation (DBS) system is adapted to assist a clinician to conduct an electrode screening review for the DBS system including screening of segmented electrodes. The clinician programmer stores software code for conducting a screening review in memory. The software code may comprise: code for providing one or more interface screens for guiding the user of the device through testing of electrode configurations of the implantable stimulation lead, wherein the code for providing applies at least one testing progression for guiding the user of the device through a defined testing order.

公开(公告)号：US09682228B2

公开(公告)日：2017-06-20

申请号：US15151397

申请日：2016-05-10

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Jodi Townsley Dubuclet

IPC: A61N1/05

CPC classification number: A61N1/0553

Abstract: A neurostimulation system is disclosed herein. The neurostimulation system includes an implantable pulse generator and an implantable therapy lead configured to be electrically coupled to the implantable pulse generator. The implantable therapy lead includes a flexible paddle electrode array with flexible electrodes. Each flexible electrode has a segmented configuration having first and second electrode segments and a flexible bridge or living hinge joining together the first and second electrode segments.

公开(公告)号：US09270137B2

公开(公告)日：2016-02-23

申请号：US14175642

申请日：2014-02-07

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： John C. Greene

IPC: H02J7/00 ,  H02J7/02 ,  A61N1/378 ,  A61N1/36 ,  H02J5/00

CPC classification number: H02J7/008 ,  A61N1/36125 ,  A61N1/3787 ,  H02J5/005 ,  H02J7/0047 ,  H02J7/0077 ,  H02J7/025 ,  H02J50/10 ,  H02J50/80 ,  H02J2007/005

Abstract: A charging energy control system includes an implantable medical device (IMD) and an external charger. The IMD receives charging energy to recharge a battery during a charging energy acceptance period and rejects the charging energy during an actual charging energy rejection period. The external charger transmits the charging energy to the IMD in order to recharge the battery. The external charger includes a charging controller configured to determine the actual charging energy rejection period, and regulate the charging energy during which the charging controller predicts a predicted charging energy rejection period of the IMD based on the actual recharging energy rejection period. The charging controller is configured to cease or reduce transmission of the charging energy during a charging energy conservation period that is at least a portion of the predicted charging energy rejection period.

Abstract translation: 充电能量控制系统包括可植入医疗装置（IMD）和外部充电器。 在充电能量接受期间，IMD接收充电能量给电池充电，并在实际的充电能量抑制期间拒绝充电能量。 外部充电器将充电能量发送到IMD，以便为电池充电。 外部充电器包括：充电控制器，被配置为确定实际的充电能量抑制周期，并且调节充电控制器根据实际充电能量抑制周期预测IMD的预测充电能量抑制周期的充电能量。 充电控制器被配置为在作为预测的充电能量抑制期间的至少一部分的充电节能期间停止或减少充电能量的传输。

公开(公告)号：US20160008593A1

公开(公告)日：2016-01-14

申请号：US14858511

申请日：2015-09-18

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Kevin D. Cairns

IPC: A61N1/05 ,  A61N1/36

CPC classification number: A61N1/0551 ,  A61B17/3401 ,  A61B17/3468 ,  A61N1/36071

Abstract: An apparatus for use in peripheral nerve field stimulation (PNFS) whereby a plurality of curved introducer needles, of varying curvatures, are provided to permit the physician to best locate the region of oligodendrocytes that contain the A Beta fibers by matching the lumbar lordosis. A wing device is also provided that is attachable to the hub of the curved needle introducer which gives the physician better ability to maneuver the needle during insertion as well as permitting tenting of the skin. The invention benefits a large number of painful disorders arising from pathology in the cervical, thoracic, and lumbar spine. In addition, this invention can also help a large number of other conditions including but not limited to failed back surgery syndrome/post-laminectomy pain, occipital/suboccipital headaches, scar pain, post herpetic neuralgia pain, mononeuritis multiplex, and pain following joint surgery (e.g., knee, hip, shoulder).

Abstract translation: 一种用于周围神经域刺激（PNFS）的装置，由此提供多个具有不同曲率的弯曲导引针，以允许医师通过匹配腰椎前凸来最佳地定位含有Aβ纤维的少突胶质细胞的区域。 还提供了一种翼片装置，其可附接到弯曲的针导入器的轮毂，其使得医生在插入期间更好地操纵针的能力以及允许皮肤的隆起。 本发明有益于宫颈，胸椎和腰椎病理学引起的大量疼痛障碍。 此外，本发明还可以帮助大量其他的病症，包括但不限于背部手术后综合征/椎板后切除术疼痛，枕骨/子宫颈外痛，疤痕疼痛，疱疹后神经痛疼痛，多发性单纯疝以及关节手术后的疼痛 （例如，膝盖，臀部，肩部）。

公开(公告)号：US20150290460A1

公开(公告)日：2015-10-15

申请号：US14635961

申请日：2015-03-02

Applicant: Advanced Neuromodulation Systems, Inc. dba St. Jude Neuromodulation Division

Inventor： Dirk De Ridder

IPC: A61N1/36 ,  A61N1/05

CPC classification number: A61N1/36082 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/36025 ,  A61N1/36085 ,  A61N1/36089 ,  A61N1/36096 ,  A61N1/36146 ,  A61N1/36171

Abstract: In certain embodiments, a method of treating mild cognitive disorder, early-stage dementia, Alzheimer's disease, or other neurological disorder, comprises: identifying the neurological disorder in a patient; operating an implantable pulse generator to generate electrical pulses; and providing the electrical pulses from the implantable pulse generator to tissue of a target site of the patient's brain, using one or more electrodes of an implantable stimulation lead, to treat the neurological disorder in the patient, wherein the target site is selected from the sites consisting of posterior cingulate cortex (PCC), inferior pariertal area, parahippocampus, precuneus, sub and pregenual anterior cingulate cortex (ACC), and pariertal area sites.

Abstract translation: 在某些实施方案中，治疗轻度认知障碍，早期痴呆，阿尔茨海默病或其他神经障碍的方法包括：鉴定患者的神经障碍; 操作植入式脉冲发生器以产生电脉冲; 以及使用植入式刺激引线的一个或多个电极将来自所述可植入脉冲发生器的电脉冲提供给所述患者大脑的靶部位的组织，以治疗患者的神经障碍，其中所述靶位点选自所述位点 包括后扣带皮层（PCC），下部亚临界区域，海马，前排，前后扣带皮层（ACC）和旁边区域。