公开(公告)号：US20220177509A1

公开(公告)日：2022-06-09

申请号：US17601326

申请日：2020-03-31

Applicant: NIPPON SHOKUBAI CO., LTD. ,  OSAKA UNIVERSITY

Inventor： Takeshi BABA ,  Hiroshi OKAMOTO ,  Yumi NOMURA ,  Satoshi OBIKA ,  Takao YAMAGUCHI

IPC: C07H19/16 ,  C07H19/06 ,  C07H1/00

Abstract: Provided is a method for producing a compound represented by formula (III) from a compound represented by formula (I) as a starting material.

公开(公告)号：US11332663B2

公开(公告)日：2022-05-17

申请号：US17097516

申请日：2020-11-13

Applicant: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION and RESEARCH SYSTEM ,  OSAKA UNIVERSITY ,  NICHIA CORPORATION

Inventor： Tsukasa Torimoto ,  Tatsuya Kameyama ,  Marino Kishi ,  Susumu Kuwabata ,  Taro Uematsu ,  Daisuke Oyamatsu

IPC: C09K11/62 ,  H01L33/50 ,  B82Y40/00 ,  B82Y20/00

Abstract: Provided is a ternary or quaternary semiconductor nanoparticle that enables the band-edge emission and a less toxic composition. A semiconductor nanoparticle is provided that contains Ag, In, and S and has an average particle size of 50 nm or less, wherein the ratio of the number of atoms of Ag to the total number of atoms of Ag and In is 0.320 or more and 0.385 or less, the ratio of the number of atoms of S to the total number of atoms of Ag and In is 1.20 or more and 1.45 or less. The semiconductor nanoparticle is adapted to emit photoluminescence having a photoluminescence lifetime of 200 ns or less upon being irradiated with light having a wavelength in a range of 350 nm to 500 nm.

公开(公告)号：US20220142577A1

公开(公告)日：2022-05-12

申请号：US17588028

申请日：2022-01-28

Applicant: OSAKA UNIVERSITY

Inventor： Tsuyoshi SEKITANI ,  Takafumi UEMURA ,  Teppei ARAKI ,  Shusuke YOSHIMOTO

IPC: A61B5/00 ,  A61B5/25 ,  A61B5/291 ,  A61B5/296 ,  A61B5/369

Abstract: A biosignal measurement apparatus is used by being affixed on a living body. The apparatus includes an affixed part that is a sheet, in which a signal-acquiring section of multiple electrodes and wiring connected to each of the electrodes are formed, and which can be freely expanded, contracted and bent and is adhesive; and a substrate that is connected to the wiring and on which a signal-processing circuit for wirelessly transmitting biosignals obtained through the wiring is mounted.
The signal-acquiring section is exposed on the surface of the affixed part and the affixed part and the substrate are stacked so that the back surface of the affixed part faces the substrate.

公开(公告)号：US20220142507A1

公开(公告)日：2022-05-12

申请号：US17585199

申请日：2022-01-26

Applicant: Sumitomo Riko Company Limited ,  Osaka University

Inventor： Wataru TAKAHASHI ,  Masanori YAMAMOTO ,  Atsuki SHIMIZU ,  Mitsuyoshi KONDO ,  Jun Taguchi ,  Hidetsugu ASANOI ,  Yoshiki SAWA ,  Shigeru MIYAGAWA

IPC: A61B5/113 ,  A61B5/00 ,  A61B5/11

Abstract: A heart failure diagnostic device includes a piezoelectric sensor sheet having flexibility and configured to output a detection signal corresponding to an input vibration. A respiratory signal acquisition unit is configured to extract, as a respiratory signal, a signal of a vibration frequency caused by respiration from the detection signal detected by the piezoelectric sensor sheet. A power spectrum calculator is configured to obtain a power spectrum of a respiratory frequency band from the respiratory signal, and a signal corrector is configured to correct the detection signal such that in the power spectrum, a maximum value of a first-order frequency component of a respiratory waveform is not smaller than 1.5 times a maximum value of a second-order frequency component of the respiratory waveform to obtain the respiratory signal.

公开(公告)号：US11325244B2

公开(公告)日：2022-05-10

申请号：US16077349

申请日：2017-02-10

Applicant: ADVANCED TELECOMMUNICATIONS RESEARCH INSTITUTE INTERNATIONAL ,  OSAKA UNIVERSITY

Inventor： Tomoyuki Noda ,  Yoshihiro Nakata ,  Hiroshi Ishiguro ,  Jun Morimoto

IPC: B25J9/08 ,  F16C35/06 ,  B25J13/08 ,  B25J17/00 ,  B25J9/10 ,  B25J17/02

Abstract: A modularized externally-driven joint structure can be used for general purposes. An externally-driven joint structure: includes a shaft member that extends in an axial direction; and a number of rotatable members that are arranged along the axial direction, and are coupled with each other by the shaft member in an axially rotatable manner. Each of the rotatable members includes a pair of face portions that face each other in the axial direction, a side wall portion that is arranged along the outer circumferential edges of the pair of face portions, and at least one coupling portion that is arranged at the face portions or the side wall portion, and is coupled with a link member constituting a link of a robot.

公开(公告)号：US20220127391A1

公开(公告)日：2022-04-28

申请号：US17571031

申请日：2022-01-07

Applicant: DAIKIN INDUSTRIES, LTD. ,  OSAKA UNIVERSITY

Inventor： Chisato HIGASHI ,  Eiji Masuda ,  Masayuki Tsuji ,  Akira Shimodo ,  Yasuhiro Nakano ,  Akihiro Oshima

IPC: C08F8/50 ,  C08F114/26

Abstract: A method for producing low-molecular-weight polytetrafluoroethylene which includes: (1) irradiating high-molecular-weight polytetrafluoroethylene with radiation to a dose of 250 kGy or higher substantially in the absence of oxygen to provide low-molecular-weight polytetrafluoroethylene having a melt viscosity at 380° C. of 1.0×102 to 7.0×105 Pa·s. Also disclosed is a powder containing the low-molecular-weight polytetrafluoroethylene, the powder being substantially free from any of perfluorooctanoic acid and salts thereof.

公开(公告)号：US20220127300A1

公开(公告)日：2022-04-28

申请号：US17428998

申请日：2020-02-10

Applicant: Osaka University

Inventor： Satoshi OBIKA ,  Takao YAMAGUCHI ,  Takaki HABUCHI ,  Go KATO ,  Takao INOUE ,  Tokuyuki YOSHIDA ,  Md Ariful ISLAM

IPC: C07H21/04

Abstract: Disclosed are a 5′-modified nucleoside and a nucleotide using the same. The nucleoside of the present invention is represented by the formula (I) below. The 5′-modified nucleoside of the present invention is usable as a substitute for a phosphorothioate-modified nucleic acid, which has a risk of, for example, accumulation in a specific organ. The 5′-modified nucleoside also has excellent industrial productivity because a diastereomer separation step is not involved in the production process thereof.

公开(公告)号：US20220111367A1

公开(公告)日：2022-04-14

申请号：US17273118

申请日：2019-08-30

Applicant: OSAKA UNIVERSITY ,  N.E. CHEMCAT CORPORATION

Inventor： Kiyotomi KANEDA ,  Takato MITSUDOME ,  Miho KIMURA ,  Yukio TAKAGI ,  Yoshiyuki WADA

IPC: B01J27/185 ,  B01J27/198 ,  C07C209/26 ,  B01J37/04

Abstract: Provided is a hydrogenation catalyst for an amide compound, containing hydroxyapatite and platinum and vanadium that are fixed on the hydroxyapatite, 15 to 80% of the surface of the platinum being covered with vanadium. The hydrogenation catalyst can promote a reduction reaction in which an amide compound is converted into an amine compound, can be used under mild conditions, and has such durability that the catalyst can be repeatedly used while retaining a high activity.

公开(公告)号：US20220088015A1

公开(公告)日：2022-03-24

申请号：US17463664

申请日：2021-09-01

Applicant: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ,  UNIVERSITÉ PARIS-EST CRÉTEIL VAL DE MARNE ,  ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) ,  OSAKA UNIVERSITY

Inventor： Geneviève DERUMEAUX ,  Daigo SAWAKI ,  Gabor CZIBIK ,  Takehiko YOSHIMITSU

IPC: A61K31/4985 ,  A61P3/00 ,  A61P9/00 ,  A61K39/395 ,  C12N15/113

Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. The inventors identified osteopontin (OPN) as a critical mediator of adipose tissue remodeling and senescence in obesity and extends this observation to related co-morbidities such as cardiomyopathy. Said result raises the possibility that inhibition of OPN activity may be of value in the prevention of cardiometabolic disease, in particular metabolic cardiomyopathy for which no specific treatment is yet available. In particular, the present invention relates to a method of treating an age-related cardiometabolic disease in an elderly subject in need thereof comprising administering to the subject a therapeutically effective amount of an osteopontin (OPN) inhibitor.

公开(公告)号：US11273518B2

公开(公告)日：2022-03-15

申请号：US16479043

申请日：2018-02-01

Applicant: OSAKA UNIVERSITY

Inventor： Hidetoshi Fujii ,  Yoshiaki Morisada ,  Yasuhiro Aoki ,  Masanori Yasuyama ,  Gen Murayama

IPC: B23K20/00 ,  B23K20/12 ,  B23K31/12 ,  B23K103/14 ,  B23K103/02 ,  B23K20/22

Abstract: A linear friction welding method capable of accurately controlling a welding temperature and capable of lowering the welding temperature is provided. The present invention is a linear friction welding method comprising: a first step of forming a welded interface by bringing one member into contact with the other member; a second step of repeatedly sliding one member and the other member on the same locus and discharging flash from the welded interface in a state where pressure is applied substantially perpendicularly to the welded interface; and a third step of forming a welded surface by stopping the sliding and setting the pressure to be not less than the yield stress and not more than the tensile strength of one member and/or the other member at a desired welding temperature.