公开(公告)号：US11320425B2

公开(公告)日：2022-05-03

申请号：US16341852

申请日：2018-03-06

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Joon Seok Lee ,  Seok Lee ,  Man Ho Choi ,  Hee Soo Pyo ,  Seung Ki Kim ,  Jae Young Kim

IPC: G01N33/543 ,  C09K11/02 ,  C09K11/77 ,  G01N21/3577

Abstract: Disclosed is a diagnostic kit for quickly diagnosing a target material with high sensitivity using nanoparticles that absorb infrared light and emit infrared light, in which the nanoparticles are maintained in particle size and have enhanced emission intensity.

公开(公告)号：US11317879B2

公开(公告)日：2022-05-03

申请号：US15631032

申请日：2017-06-23

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Deukhee Lee ,  Sangchul Hwang ,  Sung Chul Kang ,  Youngjun Kim ,  Se Hyung Park

IPC: A61B6/12 ,  A61B34/20 ,  A61B90/00 ,  A61M25/01 ,  A61M25/00 ,  A61B34/10 ,  A61B6/00

Abstract: Embodiments relate to a method for tracking a location of a surgical tool based on a radiographic image, which includes: by a photography system, photographing a surgical tool having a physical marker frame composed of three or more marker bands; by an information processor, detecting a center point of each marker band in the photographed image; and by the information processor, estimating a three-dimensional location of the surgical tool based on a distance between the detected center point and a center point of a true marker band, and a tracking apparatus for the same.

公开(公告)号：US20220131142A1

公开(公告)日：2022-04-28

申请号：US17105943

申请日：2020-11-27

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sang Baek PARK ,  Byung Kook KIM ,  Jong Ho LEE ,  Ji Won SON ,  Kyung Joong YOON ,  Hyoung Chul KIM ,  HO IL JI ,  Sung Eun YANG ,  Seung Hwan LEE ,  Joo Sun KIM

IPC: H01M4/525 ,  H01M4/505 ,  H01M4/131 ,  H01M4/134 ,  H01M4/36 ,  H01M10/0525 ,  H01M10/0562

Abstract: Disclosed are a cathode for an all-solid-state battery including a cathode thin film for an all-solid-state battery or a cathode composite membrane for an all-solid-state battery, and an all-solid-state battery including the same. The cathode for an all-solid-state battery contains a grain that has a plane having a low surface energy and has a grain boundary arranged parallel to the electron movement direction, thus effectively lowering the interfacial resistance of the thin film while suppressing the dissolution and diffusion of the transition metal, thereby improving the cycle stability of the all-solid-state battery including the same.

公开(公告)号：US20220120669A1

公开(公告)日：2022-04-21

申请号：US17498755

申请日：2021-10-12

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Joonhyun KANG ,  Il Ki HAN ,  S. Joon KWON ,  Young Min JHON

IPC: G01N21/17 ,  G01N33/00

Abstract: The present disclosure relates to a photoacoustic gas sensor for detecting the presence or absence of gas using the interaction of a laser beam and gas molecules. The integrated photoacoustic gas sensor according to an embodiment includes a light output unit; a lens unit configured to concentrate a laser beam output from the light output unit; and a photoacoustic sensing unit having a quartz tuning fork aligned on the lens unit and configured to convert a vibration, generated when the laser beam passing through the lens unit interacts with gas molecules, into an electric signal.

公开(公告)号：US20220073981A1

公开(公告)日：2022-03-10

申请号：US17466881

申请日：2021-09-03

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jae Chun RYU ,  Yoon CHO

IPC: C12Q1/6876 ,  C12Q1/6874 ,  C12N15/10

Abstract: The present invention provides a biomarker for identifying the expression of an inflammatory-response-associated gene that specifically causes a change in expression due to exposure to 2-butanone, which is harmful and found in indoor environments, and an identification method using the same, and particularly an inflammatory-response-associated gene, the expression of which is increased or decreased by exposure to 2-butanone in a human bronchial epithelial cell line model (BEAS-2B), and a method of identifying exposure and predicting an inflammatory response using the same. The biomarker of the present invention includes specific genes selected through RNA sequencing, and thus can be useful in monitoring and determining the exposure to 2-butanone in the environment, and can be utilized as a tool predicting the mechanism of inflammatory response and toxicity caused by exposure to 2-butanone.

公开(公告)号：US11261271B2

公开(公告)日：2022-03-01

申请号：US16536907

申请日：2019-08-09

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Chang Song ,  Bo Bae Seo

IPC: C08F30/02 ,  A61L27/16 ,  A61L27/36 ,  A61L27/52

Abstract: Provided is a thermosensitive phosphazene-based polymer including an amino acid ester moiety, a polyethyleneglycol moiety, and a moiety including a sulfate group linked directly or by a linker in a predetermined ratio, a method of preparing the same, and a hydrogel-formable composition including the same. For example, a hydrogel formed from the composition may be used for tissue regeneration or drug delivery or used as a storage, a body tissue regeneration inducer, or a filler in a body.

公开(公告)号：US11246939B2

公开(公告)日：2022-02-15

申请号：US16573351

申请日：2019-09-17

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sun Hwa Kim ,  Ick Chan Kwon ,  In-San Kim ,  Kwangmeyung Kim ,  Yoosoo Yang ,  Young-Ji Ko

IPC: A61K47/55 ,  A61K47/54 ,  A61K31/713 ,  C12N15/113 ,  C07K14/705 ,  A61P35/00 ,  A61K38/00

Abstract: A fusion protein-siRNA complex according to the present disclosure binds specifically to cancer cells, is taken up effectively by the cells, and exhibits anticancer activity as it is degraded by lysosomes. The fusion protein-siRNA complex provides maximized anticancer activity so that the cancer cells can be removed by autoimmunity, by inhibiting the immunity of the cancer cells and enhancing phagocytosis by macrophages.

公开(公告)号：US11241738B2

公开(公告)日：2022-02-08

申请号：US16421687

申请日：2019-05-24

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Yong Bok Lee ,  Jungwan Kim ,  Sena Jeong ,  Bok Seong Choe ,  Wonil Kwak ,  Jaeseung Byun

IPC: B22F9/10 ,  B22F9/08 ,  B33Y10/00 ,  B33Y30/00 ,  B01J2/12

Abstract: A metal powder manufacturing apparatus for a metal 3-dimensional (3D) printer includes a driving unit which generates a rotational force, a metal beam connected to the driving unit to receive the rotational force from the driving unit and having one end disposed in a vacuum chamber, and a shaft support which supports an outer circumference of the metal beam using a magnetic force for relative movement of the metal beam in a lengthwise direction of the metal beam, wherein the shaft support is disposed such that an inner side is spaced apart a predetermined distance from the outer circumference of the metal beam, and can support the metal beam at an adjusted relative distance from the metal beam.

公开(公告)号：US20220036054A1

公开(公告)日：2022-02-03

申请号：US17388013

申请日：2021-07-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ig Jae KIM ,  Yu-Jin HONG ,  Hyeonjung PARK ,  Minsoo KIM ,  Ikkyu CHOI

IPC: G06K9/00 ,  G06K9/32 ,  G06K9/62 ,  G06K9/46

Abstract: Embodiments relate to a companion animal identification method including acquiring a preview image for capturing a face of a target companion animal, checking if the face of the target companion animal is aligned according to a preset criterion, capturing the face of the target companion animal when it is determined that the face of the target companion animal is aligned, and identifying the target companion animal by extracting features from a face image of the target companion animal having an aligned face view, and an identification system for performing the same.

公开(公告)号：US20220025092A1

公开(公告)日：2022-01-27

申请号：US17334437

申请日：2021-05-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hae Jung SON ,  Eul-Yong SHIN ,  Sungmin PARK ,  Taehee KIM

IPC: C08F228/06 ,  H01L51/42 ,  H01L51/00

Abstract: A self-healing conjugated polymer is disclosed. The self-healing conjugated polymer has hydrogen bonding functional groups introduced into its side chains. Due to this structure, the conjugated polymer is imparted with the ability to recover through self-healing while maintaining its inherent properties (for example, physical and electrical properties). Based on this effective self-healing ability, the conjugated polymer is expected to find application as a biomaterial, a pharmaceutical material, a nonlinear optical material or an organic electronic material.