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131.发明授权公开(公告)号：US10325684B2
公开(公告)日：2019-06-18
申请号：US15645008
申请日：2017-07-10
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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132.发明授权公开(公告)号：US10311973B2
公开(公告)日：2019-06-04
申请号：US15204707
申请日：2016-07-07
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman , Siavosh Rezvan Behbahani
Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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133.发明授权公开(公告)号：US10297351B2
公开(公告)日：2019-05-21
申请号：US15645034
申请日：2017-07-10
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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134.发明授权公开(公告)号：US10290376B2
公开(公告)日：2019-05-14
申请号：US15645102
申请日：2017-07-10
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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135.发明申请公开(公告)号：US20190087536A1
公开(公告)日：2019-03-21
申请号：US16084962
申请日：2016-09-09
Applicant: uBiome. Inc
Inventor： Zachary APTE , Jessica Richman , Daniel Almonacid , Siavosh Rezvan Behbahani
IPC: G06F19/18 , C12Q1/6883 , C12Q1/689
Abstract: Methods, compositions, and systems are provided for detecting one or more a thyroid health issues by characterizing the microbiome of an individual, monitoring such effects, and/or determining, displaying, or promoting a therapy for the thyroid health issue. Methods, compositions, and systems are also provided for generating and comparing microbiome composition and/or functional diversity datasets.
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Patent Agency Ranking
136.发明申请公开(公告)号：US20190085396A1
公开(公告)日：2019-03-21
申请号：US16084946
申请日：2016-09-09
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Siavosh Rezvan Behbahani
IPC: C12Q1/6883 , C12Q1/689 , G06F19/22 , G06F19/24 , G16H50/20
Abstract: Methods, compositions, and systems are provided for detecting one or more a gastrointestinal issues by characterizing the microbiome of an individual, monitoring such effects, and/or determining, displaying, or promoting a therapy for the gastrointestinal issue. Methods, compositions, and systems are also provided for generating and comparing microbiome composition and/or functional diversity datasets. Methods, compositions, and systems are also provided for generating a characterization model and/or therapy model for constipation issues, diarrhea issues, hemorrhoids issues, bloating issues, and lactose intolerance issues.
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137.发明申请公开(公告)号：US20190078142A1
公开(公告)日：2019-03-14
申请号：US16115542
申请日：2018-08-28
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Elisabeth Bik , Sara W. Bird , Luis E. Leon , Pamela A. Nieto , Victor Alegria-Mera , Cristian Bravo , Juan P. Cardenas , Paulo Covarrubias , Sarah L. Gupta , Kira Harman , Juan Jimenez , Felipe Melis-Arcos , Camila F. Navas , Harold Nunez , Eduardo Olivares , Nicolas Ordenes-Aenishanslins , Francisco J. Ossandon , Ignacio Varas , Patricia Vera-Wolf , Donna Marie B. Hongo , Laurens Kraal , Nathaniel A. Walton , Amanda Morton , Juan P. Bustamante , Kwasi Addae , Graham Gass , Katia Soto-Liebe , Juan A. Ugalde , Eduardo H. Morales , Daniel Almonacid , Jessica Richman
Abstract: Embodiments of a method and/or system for characterizing one or more female reproductive system-related conditions can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process associated with the one or more female reproductive system-related conditions, based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a female reproductive system-related characterization process for the one or more female reproductive system-related conditions, and/or determining one or more therapies.
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公开(公告)号：US20190062010A1
公开(公告)日：2019-02-28
申请号：US16115536
申请日：2018-08-28
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Constance Norris , Rodrigo Ortiz
Abstract: Embodiments of a device for protecting and sealing the opening of a container. This device is a one-piece made plug for a flask or container, comprising at least one passing channel, and at least one structural flow regulator barrier, allowing the passing of solid elements. The structural regulator barrier comprises at least a gate to regulate the passing and connection between the inside space and the outside space of the container in a unidirectional and/or bidirectional way. An embodiment includes a method and a mold for manufacturing such a device.
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公开(公告)号：US20190050534A1
公开(公告)日：2019-02-14
申请号：US16047840
申请日：2018-07-27
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Inti Pedroso , Victoria Dumas , Paz Tapia , Rodrigo Ortiz , Catalina Valdivia , Victor Alegria , Elisabeth M. Bik , Maureen Hitschfeld
IPC: G06F19/24 , C12Q1/6888 , G06F19/12 , G16H70/60
Abstract: Embodiments of a method and/or system for characterizing one or more microorganism-related conditions can include: determining a microorganism dataset associated with a set of subjects; and with a set of microsome characterization modules, applying analytical techniques to perform a characterization process for the one or more microorganism-related conditions based on the microorganism dataset.
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公开(公告)号：US20180362967A1
公开(公告)日：2018-12-20
申请号：US16013858
申请日：2018-06-20
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Juan Jimenez , Rodrigo Ortiz , Eduardo Morales , Paulo Covarrubias , Eduardo Olivares , Nicolas Ordenes , Luis Leon
IPC: C12N15/10
Abstract: Embodiments of a method 100 and/or system 200 or library preparation for sequencing associated with microorganisms can include: preparing a set of unique molecular identifier (UMI)-based molecules associated with one or more targets; preparing a set of sequencing-based primers; generating a set of tagged target molecules based on the set of UMI-based molecules and one or more samples associated with the one or more targets; and/or generating a set of sequencing-ready tagged target molecules based on the tagged target molecules and the set of sequencing-based primers.
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