公开(公告)号：US20210213442A1

公开(公告)日：2021-07-15

申请号：US17144624

申请日：2021-01-08

Applicant: Beckman Coulter, Inc.

Inventor： John M. WALLACH ,  Xihai MU

IPC: B01L3/00 ,  G01N33/487 ,  G01N33/84 ,  G01N27/403

Abstract: An ion selective electrode (“ISE”) assembly may be installed within a sample path of a biological testing system to measure ion concentration within sample fluid flowing through the sample path. A transducer membrane is placed within a housing and positioned to contact the sample path. A threaded portion is advanced into a socket of the housing and forces the membrane against a sealing portion of the sample path to prevent retention of sample fluid within the housing after testing. Sealing may be accomplished without adhesives or sealants and instead relies upon mechanical pressure of the threaded portion. Another implementation includes a reference measuring electrode and several ion measuring electrodes combined into a single housing. Another implementation includes a reference measuring electrode and several ion measuring electrodes combined into a cartridge that includes a sample well instead of a sample path.

公开(公告)号：US20210139953A1

公开(公告)日：2021-05-13

申请号：US17150106

申请日：2021-01-15

Applicant: Beckman Coulter, Inc.

Inventor： Jeffrey J. Corpstein ,  Evan Farthing ,  Thomas G. Keen ,  Jianli Zhao ,  Asmita Patel ,  Yuandan Liu ,  Cuong N. Hoang ,  Emmet Welch

IPC: C12Q1/6806 ,  H01F1/00 ,  H01F1/36

Abstract: A magnetic particle is disclosed. The magnetic particle comprises a magnetic material having a maximum field strength in a range of from about 20 emu/g to about 250 emu/g and a remanence in a range of from about 0 emu/g to about 30 emu/g. The magnetic particle further comprises an outer surface containing a ligand. The ligand interacts with an analyte of interest in the sample solution.

公开(公告)号：US10997829B2

公开(公告)日：2021-05-04

申请号：US16389034

申请日：2019-04-19

Applicant: Beckman Coulter, Inc.

Inventor： Francisco Bolanos ,  Marco T. Gonzalez ,  Enrique Olivera

IPC: G08B5/36 ,  G02B27/32 ,  G03B21/20 ,  G03B21/14 ,  G02B30/56 ,  F21Y115/10

Abstract: Embodiments of the present disclosure relate generally to a projecting status indicator for use in connection with a laboratory machine or instrument (collectively referred to as a “unit”). The indicator projects a projected visible light image or beam of light in a line directly above a particular unit so that lab personnel can tell the status of the unit from a distance. In a specific embodiment, the indicator projects an extended line of light on a ceiling above the unit, rather than a small point of light.

公开(公告)号：US10997709B2

公开(公告)日：2021-05-04

申请号：US16313581

申请日：2017-06-30

Applicant: Beckman Coulter, Inc.

Inventor： Tadashi Haga ,  Tomohiko Takeuchi

IPC: G06T7/00 ,  B01L3/00 ,  G01N35/10 ,  G06T7/90

Abstract: An automated analysis instrument operates to detect inadequate dispensation of a fluidic substance on a tray. The instrument includes an image capturing device to capture an image of at least a portion of the tray including a receptacle portion and a surrounding portion around the receptacle portion. The instrument then identifies the surrounding portion of the at least the portion of the tray in the image, evaluates color components of the image corresponding to the surrounding portion of the at least the portion of the tray, and determines whether the fluidic substance is present on the surrounding portion of the at least the portion of the tray based on at least one of the color components.

公开(公告)号：US20210108994A1

公开(公告)日：2021-04-15

申请号：US17066195

申请日：2020-10-08

Applicant: Beckman Coulter, Inc.

Inventor： Carol Quon

IPC: G01N1/30

Abstract: The present disclosure relates to a staining methodology employing a particle contrast agent composition. The compositions described herein are capable of rapidly staining cells in a single step. The particle contrast agent composition can be comprised of a combination of one or more particle contrast agents, one or more permeabilizing agents, and one or more fixing agents. The particle contrast agent composition can include Basic Fuchsin; at least one of Brilliant Cresyl Blue, Azure B, Crystal Violet and New Methylene Blue; one or more permeabilizing agents; and Gluteraldehyde.

公开(公告)号：US20210072268A1

公开(公告)日：2021-03-11

申请号：US16468430

申请日：2017-12-08

Applicant: Beckman Coulter, Inc.

Inventor： Eric VARLET ,  Sohrab FARAMARZI OGHANI ,  Martin BUÉ ,  Pr. El Ghazali TALBI

IPC: G01N35/00 ,  G16H10/40 ,  G16H40/67

Abstract: In a scenario where a laboratory is required to perform a plurality of tests on biological samples from a plurality of tubes in a manner that satisfies certain constraints, it is possible that the laboratory could handle the samples and assign them to machines in a manner which ensures that the relevant constraints are met. This could include using matrices and optimization functions to represent tubes, tests, machines and prescriptions, and could also include dynamically determining whether and how to aliquot the samples so as to meet the constraints given the conditions under which the samples would be processed.

公开(公告)号：US20210041345A1

公开(公告)日：2021-02-11

申请号：US16984363

申请日：2020-08-04

Applicant: Beckman Coulter, Inc.

Inventor： Carlos RAMIREZ ,  Ana FORTUN ,  Bentahar AHMED

IPC: G01N15/14

Abstract: Methods and systems for detecting and reporting subpopulations of neutrophils may involve using a nonce parameter to elucidate one or more other cell population parameters. Methods and systems for detecting and reporting subpopulations of neutrophils may involve structuring reports to elucidate one or more cell population parameters, particularly, but not exclusively, where the report of a cell population parameter might otherwise be ambiguous or a higher than usual likelihood of confusion.

公开(公告)号：US20210011005A1

公开(公告)日：2021-01-14

申请号：US16925943

申请日：2020-07-10

Applicant: Beckman Coulter, Inc.

Inventor： Liliana TEJIDOR ,  Robert T. MAGARI ,  Diana CAREAGA ,  Mohamad HASAN ,  Sanghyuk SHIN

IPC: G01N33/50 ,  G01N15/10 ,  G01N15/14

Abstract: Systems and methods for characterizing immune response to infection using cellular analysis, such as a hematological cellular analyzer. In some instances, the immune response may be characterized as normal or abnormal based on one or more blood cell population parameters. In some instances, abnormal characterization may be used to identify patients with sepsis or at elevated risk of developing sepsis.

公开(公告)号：US10886009B2

公开(公告)日：2021-01-05

申请号：US14844334

申请日：2015-09-03

Applicant: Beckman Coulter, Inc.

Inventor： Steven P. Rivers ,  Jeffrey J. Kotula ,  Shilpa Taneja

IPC: G16H10/40 ,  G16H10/60

Abstract: A system, method, and apparatus for an integrated console environment for diagnostic instruments are disclosed. An example apparatus includes a laboratory analyzer configured to generate patient sample result data by performing an analysis on a biological sample from a patient and quality control data by performing an analysis on a control biological sample with known properties. The example apparatus also includes a first laboratory instrument memory configured to locally store the patient sample result data among a plurality of other patient sample result data and a first data access component at a first address configured to provide access to the first laboratory instrument memory. The example apparatus further includes a second laboratory instrument memory configured to locally store the quality control data among a plurality of other quality control data and a second data access component at a second address configured to provide access to the second laboratory instrument memory.

公开(公告)号：USD899623S1

公开(公告)日：2020-10-20

申请号：US29645493

申请日：2018-04-26

Applicant: Beckman Coulter, Inc.

Designer： Takayuki Mizutani ,  Shigeru Fujii ,  Kazuki Umebara