公开(公告)号：US20140102049A1

公开(公告)日：2014-04-17

申请号：US13654194

申请日：2012-10-17

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Stephen D. Pacetti ,  Ni Ding

IPC: A61L31/08

CPC classification number: A61L31/08 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/428 ,  A61L2300/608 ,  A61L2300/61 ,  A61L2420/08

Abstract: This invention relates to methods of including an oxygen-sensitive macrocyclic triene on an implantable medical device wherein the device includes separate antioxidant-containing layers above, below or both above and below the drug reservoir layer containing the macrocyclic triene.

Abstract translation: 本发明涉及在可植入医疗装置上包含氧敏感性大环三烯的方法，其中该装置在含有大环三烯的药物贮存层上方，下方或两者以上含有分离的抗氧化剂层。

公开(公告)号：US20140072695A1

公开(公告)日：2014-03-13

申请号：US14078212

申请日：2013-11-12

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Victoria M. Gong ,  Stephen D. Pacetti ,  Anthony S. Andreacchi ,  Shih-Hsiung Albert Yuan

IPC: A61L29/08

CPC classification number: A61L29/08 ,  A61M25/1027 ,  B05D1/002 ,  B05D1/26 ,  B05D3/0254

Abstract: A system and method for coating an expandable member of a medical device comprises providing a dispenser in fluid communication with a fluid source with the dispenser having at least one outlet to dispense fluid of the fluid source therefrom. The outlet(s) of the dispenser is positioned proximate a surface of an expandable member, with relative movement between the outlet(s) and the surface of the expandable member established along a coating path, and fluid is dispensed from the dispenser to form a substantially continuous bead of fluid between the at least one outlet and the surface of the expandable member along the coating path, and simultaneously drying the fluid while dispensing the fluid from the dispenser to control flow of fluid on the surface of the expandable member. The fluid source can include a variety of therapeutic agents.

Abstract translation: 用于涂覆医疗装置的可扩张构件的系统和方法包括提供与流体源流体连通的分配器，分配器具有至少一个出口，用于从其中分配流体源的流体。 分配器的出口定位在可扩张构件的表面附近，其中出口与沿着涂覆路径建立的可膨胀构件的表面之间的相对运动，并且流体从分配器分配以形成 在所述至少一个出口和所述可扩张构件的所述表面之间沿着所述涂覆路径的基本上连续的流体珠，并且同时干燥所述流体，同时从所述分配器分配所述流体以控制所述可膨胀构件的表面上的流体的流动。 流体源可以包括各种治疗剂。

公开(公告)号：US20130276412A1

公开(公告)日：2013-10-24

申请号：US13846711

申请日：2013-03-18

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Stephen D. Pacetti

IPC: B65B3/00

CPC classification number: B65B3/003 ,  A61F2/91 ,  A61F2250/0068 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L33/00 ,  A61L2300/416 ,  A61L2300/43 ,  A61L2300/602 ,  B05D3/0218

Abstract: A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The structural element, or a stent having such a structural element, is immersed in a solution or a composition, and the composition or solution is allowed to fill the lumen. The composition or solution may comprise a therapeutic agent.

Abstract translation: 一种将组合物装载到支架的结构元件中的方法，其中结构元件由腔和至少一个开口限定，以进入内腔。 将结构元件或具有这种结构元件的支架浸入溶液或组合物中，并使组合物或溶液填充内腔。 组合物或溶液可以包含治疗剂。

公开(公告)号：US20130142940A1

公开(公告)日：2013-06-06

申请号：US13720551

申请日：2012-12-19

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Stephen D. Pacetti

IPC: A61F2/82

CPC classification number: A61F2/82 ,  B05D1/002

Abstract: A method for removing excess coating from a stent involves simultaneously applying a coating substance to the stent, rotating the stent about a first axis of rotation, and rotating the stent about a second axis of rotation parallel to the first axis of rotation. An apparatus for removing excess coating from a stent includes a first system configured to rotate the stent about an axis of rotation, a fixture configured to support the stent such that a longitudinal axis of the stent is generally parallel to the axis of rotation, and a second system configured to rotate the stent about the longitudinal axis of the stent while the stent is supported by the fixture.

Abstract translation: 用于从支架去除多余涂层的方法包括同时将涂层物质施加到支架上，使支架围绕第一旋转轴线旋转，并使支架围绕平行于第一旋转轴线的第二旋转轴旋转。 用于从支架去除多余涂层的装置包括构造成围绕旋转轴线旋转支架的第一系统，被配置为支撑支架的夹具，使得支架的纵向轴线大致平行于旋转轴线，并且 第二系统构造成在支架由支架支撑的同时围绕支架的纵向轴线旋转支架。