公开(公告)号：US07351821B2

公开(公告)日：2008-04-01

申请号：US11640417

申请日：2006-12-18

Applicant: Annika Björe ,  Magnus Björsne ,  David Cladingboel ,  Kurt-Jürgen Hoffmann ,  John Pavey ,  Fritiof Pontén ,  Gert Strandlund ,  Peder Svensson ,  Colin Thomson ,  Michael Wilsterman

Inventor： Annika Björe ,  Magnus Björsne ,  David Cladingboel ,  Kurt-Jürgen Hoffmann ,  John Pavey ,  Fritiof Pontén ,  Gert Strandlund ,  Peder Svensson ,  Colin Thomson ,  Michael Wilsterman

IPC: C07D265/36 ,  C07D498/02

CPC classification number: C07D498/08

Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

Abstract translation: 提供式I化合物，其中R 1，R 2，R 3，R 4，R 4，R 4， A，B和G具有描述中给出的含义，其可用于预防和治疗心律失常，特别是心房和室性心律失常 。

公开(公告)号：US07164017B2

公开(公告)日：2007-01-16

申请号：US10317195

申请日：2002-12-12

Applicant: David Cladingboel ,  John Pavey ,  Colin Thomson

Inventor： David Cladingboel ,  John Pavey ,  Colin Thomson

IPC: C07D265/36 ,  C07D498/02

CPC classification number: C07D498/08

Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

公开(公告)号：US20100110830A1

公开(公告)日：2010-05-06

申请号：US12447683

申请日：2007-08-21

Applicant: Colin Thomson

Inventor： Colin Thomson

IPC: G01V1/38 ,  G01V1/30

CPC classification number: G01V1/303

Abstract: There is provided a method of direct waveform inversion of turning waves (311, 312, 313) to determine parameters characterizing properties of the earth or sub-sections of the earth, particularly of parts of the earth which are capable of trapping hydrocarbons with the inversion yielding from the wavefield of turning waves information representing or being equivalent to velocities or slownesses and/or the gradient of velocities or slownesses, particularly by evaluating wavefield data in the vicinity of turning points (33). The method can be applied sequentially as a survey sinking method.

Abstract translation: 提供了一种转向波（311,312,313）的直接波形反转的方法，以确定表征地球的地球或子部分，特别是地球部分能够捕获碳氢化合物的反应的特性的参数 从表示或相当于速度或慢度的转向波的波场产生和/或速度或慢度的梯度，特别是通过评估转折点附近的波场数据（33）。 该方法可以作为调查沉没法顺序应用。

公开(公告)号：US20070282103A1

公开(公告)日：2007-12-06

申请号：US10581143

申请日：2004-12-02

Applicant: Michael Butters ,  Richard Wisedale ,  Mathew Welham ,  Colin Thomson ,  Andrew Watts

Inventor： Michael Butters ,  Richard Wisedale ,  Mathew Welham ,  Colin Thomson ,  Andrew Watts

IPC: C07D239/00

CPC classification number: C07D497/04 ,  C07D513/04

Abstract: A method for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof; from a compound of the formula: (IV); wherein L represents a leaving group.

Abstract translation: 一种制备式（I）化合物或其药学上可接受的盐或溶剂合物的方法; 由式（IV）表示的化合物： 其中L表示离去基团。

公开(公告)号：US4001422A

公开(公告)日：1977-01-04

申请号：US598723

申请日：1975-07-24

Applicant: John C. Danilewicz ,  Anthony G. Evans ,  Allan L. Ham ,  Colin Thomson

Inventor： John C. Danilewicz ,  Anthony G. Evans ,  Allan L. Ham ,  Colin Thomson

IPC: C07D401/04 ,  A61K20060101 ,  A61K31/445 ,  A61K31/47 ,  A61K31/495 ,  A61K31/505 ,  A61P9/04 ,  C07D20060101 ,  C07D207/12 ,  C07D211/24 ,  C07D211/30 ,  C07D211/34 ,  C07D211/44 ,  C07D211/56 ,  C07D211/58 ,  C07D211/70 ,  C07D213/54 ,  C07D213/56 ,  C07D213/72 ,  C07D235/26 ,  C07D239/00 ,  C07D239/72 ,  C07D239/94 ,  C07D295/14 ,  C07D295/16 ,  C07D401/00 ,  C07D401/02 ,  C07D401/14 ,  C07D403/04 ,  C07D403/14 ,  C07D409/04 ,  C07D491/04 ,  C07D491/056 ,  C07F9/02 ,  A01N9/22

CPC classification number: Y02P20/55

Abstract: 6,7-Dialkoxy-4-aminoquinazoline cardiac stimulants and synthetic methods for the preparation thereof.

公开(公告)号：US20100217000A1

公开(公告)日：2010-08-26

申请号：US12638415

申请日：2009-12-15

Applicant: Michael Butters ,  Richard Wisedale ,  Matthew James Welham ,  Colin Thomson ,  Andrew Watts

Inventor： Michael Butters ,  Richard Wisedale ,  Matthew James Welham ,  Colin Thomson ,  Andrew Watts

IPC: C07D471/04

CPC classification number: C07D497/04 ,  C07D513/04

Abstract: A method for the preparation of a compound of formula (1) or a pharmaceutically acceptable salt or solvate thereof; from a compound of the formula: (IV); wherein L represents a leaving group.

Abstract translation: 一种制备式（1）化合物或其药学上可接受的盐或溶剂合物的方法; 由式（IV）表示的化合物： 其中L表示离去基团。

公开(公告)号：US20070117799A1

公开(公告)日：2007-05-24

申请号：US11640417

申请日：2006-12-18

Applicant: Annika Bjore ,  Magnus Bjorsne ,  David Cladingboel ,  Kurt-Jurgen Hoffmann ,  John Pavey ,  Fritiof Ponten ,  Gert Strandlund ,  Peder Svensson ,  Colin Thomson ,  Michael Wilsterman

Inventor： Annika Bjore ,  Magnus Bjorsne ,  David Cladingboel ,  Kurt-Jurgen Hoffmann ,  John Pavey ,  Fritiof Ponten ,  Gert Strandlund ,  Peder Svensson ,  Colin Thomson ,  Michael Wilsterman

IPC: A61K31/538 ,  C07D491/04

CPC classification number: C07D498/08

Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

Abstract translation: 提供式I化合物，其中R 1，R 2，R 3，R 4，R 4，R 4， A，B和G具有描述中给出的含义，其可用于预防和治疗心律失常，特别是心房和室性心律失常 。

公开(公告)号：US09158018B2

公开(公告)日：2015-10-13

申请号：US13333620

申请日：2011-12-21

Applicant: Rodrigo Fuck ,  Christopher H. Chapman ,  James Rickett ,  Colin Thomson

Inventor： Rodrigo Fuck ,  Christopher H. Chapman ,  James Rickett ,  Colin Thomson

IPC: G06G7/48 ,  G01V1/30 ,  G01V1/28 ,  G06F17/50

CPC classification number: G01V1/301 ,  G01V1/282 ,  G01V1/307 ,  G06F17/50

Abstract: Forward modeling is performed to compute a response of a target structure, the forward modeling accounting for distortion of a reflected signal from a reflector in the target structure. Waveform inversion is performed using the response of the forward modeling.

Abstract translation: 执行正向建模以计算目标结构的响应，正向建模考虑来自目标结构中的反射器的反射信号的失真。 使用正向建模的响应来执行波形反转。

公开(公告)号：US20060166980A1

公开(公告)日：2006-07-27

申请号：US11385861

申请日：2006-03-22

Applicant: Annika Bjore ,  Magnus Bjorsne ,  David Cladingboel ,  Kurt-Jurgen Hoffmann ,  John Pavey ,  Fritiof Ponten ,  Gert Strandlund ,  Peder Svensson ,  Colin Thomson ,  Michael Wilsterman

Inventor： Annika Bjore ,  Magnus Bjorsne ,  David Cladingboel ,  Kurt-Jurgen Hoffmann ,  John Pavey ,  Fritiof Ponten ,  Gert Strandlund ,  Peder Svensson ,  Colin Thomson ,  Michael Wilsterman

IPC: C07D487/04 ,  A61K31/538

CPC classification number: C07D498/08

Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

公开(公告)号：US3966710A

公开(公告)日：1976-06-29

申请号：US523024

申请日：1974-11-12

Applicant: James W. McFarland ,  Colin Thomson

Inventor： James W. McFarland ,  Colin Thomson

IPC: C07D333/24 ,  C07D499/00 ,  C07D499/46 ,  C07D499/68

CPC classification number: C07D333/24 ,  C07D499/00 ,  Y10S514/96 ,  Y10S514/962

Abstract: 6-(Aminomethyl substituted phenyl- and thienylacetamido)-penicillanic acid and esters, and synthetic methods for the preparation thereof.