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公开(公告)号：US11998027B2
公开(公告)日：2024-06-04
申请号：US17829416
申请日：2022-06-01
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , C12N9/14 , C12N9/18 , C12Y301/01 , A23V2002/00 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US11910807B2
公开(公告)日：2024-02-27
申请号：US17555731
申请日：2021-12-20
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , C12N9/14 , C12N9/18 , C12Y301/01 , A23V2002/00 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US20230257744A1
公开(公告)日：2023-08-17
申请号：US18001269
申请日：2021-06-09
Applicant: ERBER AKTIENGESELLSCHAFT
Inventor： Florian KRAINER , Lukas STURMBERGER , Patricia MENCZIK
IPC: C12N15/113 , C12P21/00 , C12N15/81
CPC classification number: C12N15/113 , C12N15/815 , C12P21/00
Abstract: A promoter or variant thereof has increased relative expression efficiency, in particular a formate dehydrogenase promoter variant has increased relative expression efficiency, and a method provides for recombinant protein production and for increasing the relative expression efficiency of a nucleotide sequence having promoter activity.
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公开(公告)号：US20220002806A1
公开(公告)日：2022-01-06
申请号：US17311210
申请日：2019-12-06
Applicant: ERBER AKTIENGESELLSCHAFT
Inventor： Bertrand Grenier , Veronika Nagl , Gerd Schatzmayr , Eva-Maria Binder
IPC: C12Q1/6883 , G01N33/50 , C12Q1/02
Abstract: The present invention relates to a novel method for detecting zearalenone (ZEN) effect comprising determining the expression level of at least one miRNA in a test sample, as well as to a novel use of at least one miRNA for detecting zearalenone (ZEN) effect in a test sample.
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15.发明申请公开(公告)号：US20200268819A1
公开(公告)日：2020-08-27
申请号：US16473643
申请日：2017-12-14
Applicant: Erber Aktiengesellschaft
Inventor： Elisabeth MAYER , Barbara NOVAK , Christina SCHWAB-ANDICS , Ursula HOFSTÄTTER-SCHAEHS , Gerd SCHATZMAYR
IPC: A61K36/484 , A23K10/30 , A23K20/163 , A61K31/704
Abstract: The use of at least one Glycyrrhiza plant preparation selected from the group of flour of a whole, dried Glycyrrhiza plant, flour of the leaves of the dried Glycyrrhiza plant, flour of roots of the dried Glycyrrhiza plant, aqueous dry extract of the Glycyrrhiza plant, aqueous/ethanolic dry extract of the Glycyrrhiza plant, aqueous extract of the Glycyrrhiza plant, optionally together with at least one excipient, for reducing the toxic effect of at least one polypeptide fungitoxin in agrarian products.
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Patent Agency Ranking
16.发明申请公开(公告)号：US20200010812A1
公开(公告)日：2020-01-09
申请号：US16576811
申请日：2019-09-20
Applicant: Erber Aktiengesellschaft
Inventor： Eva-Maria BINDER , Barbara Weber , Claudia Bernard
Abstract: An alcohol dehydrogenase of sequence ID numbers 2, 3 or 4 containing metal ions and a quinone cofactor, or in addition, a functional variant exhibiting a sequence identity of at least 80%, preferably at least 86%, especially preferred at least 89% and at least one redox cofactor for the transformation of at least one trichothecene exhibiting a hydroxyl group on the C-3 atom, as well as a method for the enzymatic transformation of trichothecenes and a trichothecene-transforming additive.
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公开(公告)号：US10526585B2
公开(公告)日：2020-01-07
申请号：US15561545
申请日：2015-03-27
Applicant: Erber Aktiengesellschaft
Inventor： Eva-Maria Binder , Barbara Weber , Claudia Bernard
Abstract: A alcohol dehydrogenase of sequence ID no. 1 containing metal ions and a quinone cofactor, or in addition, a functional variant exhibiting a sequence identity of at least 80%, preferably at least 86%, especially preferred at least 89% and at least one redox cofactor for the transformation of at least one trichothecene exhibiting a hydroxyl group on the C-3 atom, as well as a method for the enzymatic transformation of trichothecenes and a trichothecene-transforming additive.
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18.发明申请公开(公告)号：US20180080011A1
公开(公告)日：2018-03-22
申请号：US15561545
申请日：2015-03-27
Applicant: Erber Aktiengesellschaft
Inventor： Eva-Maria BINDER , Barbara WEBER , Claudia BERNARD
Abstract: A alcohol dehydrogenase of sequence ID no. 1 containing metal ions and a quinone cofactor, or in addition, a functional variant exhibiting a sequence identity of at least 80%, preferably at least 86%, especially preferred at least 89% and at least one redox cofactor for the transformation of at least one trichothecene exhibiting a hydroxyl group on the C-3 atom, as well as a method for the enzymatic transformation of trichothecenes and a trichothecene-transforming additive.
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19.发明申请POLYPEPTIDE FOR HYDROLYTIC CLEAVAGE OF ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDE THEREOF AS WELL AS A POLYPEPTIDE CONTAINING AN ADDITIVE, USE OF SAME AS WELL AS A PROCESS 审中-公开用于ZEARALENONE和/或ZEARALENONE衍生物的水解溶剂的多肽，其分离的多核苷酸作为包含添加剂的多肽，使用相同方式作为过程公开(公告)号：US20160345606A1
公开(公告)日：2016-12-01
申请号：US14914671
申请日：2014-08-27
Applicant: ERBER AKTIENGESELLSCHAFT
Inventor： Sebastian FRUHAUF , Michaela THAMHESL , Martin PFEFFER , Dieter MOLL , Gerd SCHATZMAYR , Eva Maria BINDER
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , A23V2002/00 , C12N9/14 , C12N9/18 , C12Y301/01 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
Abstract translation: 本发明涉及一种用于玉米赤霉烯酮和/或至少一种玉米赤霉烯酮衍生物的水解切割的多肽，所述多肽是具有选自SEQ ID NO：1-15或其功能变体的氨基酸序列的水解酶， 其中所述功能变体的序列与所述氨基酸序列中的至少一个至少40％相同。 本发明还涉及：含有该多肽的添加剂; 编码多肽的分离的多核苷酸; 以及使用该多肽水解切割玉米赤霉烯酮和/或至少一种玉米赤霉烯酮衍生物的方法。
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公开(公告)号：US20160319258A1
公开(公告)日：2016-11-03
申请号：US15054232
申请日：2016-02-26
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian FRUHAUF , Michaela THAMHESL , Martin PFEFFER , Dieter MOLL , Gerd SCHATZMAYR , Eva Maria BINDER
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , A23V2002/00 , C12N9/14 , C12N9/18 , C12Y301/01 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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