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1.发明申请公开(公告)号：US20180235255A1
公开(公告)日：2018-08-23
申请号：US15553218
申请日：2015-02-24
Applicant: ERBER AKTIENGESELLSCHAFT
Inventor： Markus ALESCHKO , Corinna KERN , Dieter MOLL , Eva Maria BINDER , Gerd SCHATZMAYR
IPC: A23K10/14 , A23K50/30 , A23K50/60 , A23K20/147 , C12N9/18
CPC classification number: A23K10/14 , A23K20/147 , A23K50/30 , A23K50/60 , C12N9/18
Abstract: The invention relates to fusarium toxin-cleaving polypeptide variants of a fusarium toxin carboxyl esterase with the SEQ ID NO:46. Each of the polypeptide variants has an amino acid sequence shortened by 47 amino acids at the N terminus, and the amino acid sequences have at least 70%, preferably 80%, in particular 100%, sequence identity, namely SEQ ID NO:1, to the amino acid sequence portion 48-540 of the SEQ ID NO:46. The invention also relates to isolated polynucleotides which code for the polypeptide variants, to a fusarium toxin-cleaving additive containing at least one polypeptide variant and optionally at least one auxiliary agent, to the use of the polypeptide variants or the additive, and to a method for hydrolytically cleaving at least one fusarium toxin.
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公开(公告)号：US20220322701A1
公开(公告)日：2022-10-13
申请号：US17829416
申请日：2022-06-01
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian FRUHAUF , Michaela THAMHESL , Martin PFEFFER , Dieter MOLL , Gerd SCHATZMAYR , Eva Maria BINDER
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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3.发明申请公开(公告)号：US20200268819A1
公开(公告)日：2020-08-27
申请号：US16473643
申请日：2017-12-14
Applicant: Erber Aktiengesellschaft
Inventor： Elisabeth MAYER , Barbara NOVAK , Christina SCHWAB-ANDICS , Ursula HOFSTÄTTER-SCHAEHS , Gerd SCHATZMAYR
IPC: A61K36/484 , A23K10/30 , A23K20/163 , A61K31/704
Abstract: The use of at least one Glycyrrhiza plant preparation selected from the group of flour of a whole, dried Glycyrrhiza plant, flour of the leaves of the dried Glycyrrhiza plant, flour of roots of the dried Glycyrrhiza plant, aqueous dry extract of the Glycyrrhiza plant, aqueous/ethanolic dry extract of the Glycyrrhiza plant, aqueous extract of the Glycyrrhiza plant, optionally together with at least one excipient, for reducing the toxic effect of at least one polypeptide fungitoxin in agrarian products.
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Patent Agency Ranking
4.发明申请POLYPEPTIDE FOR HYDROLYTIC CLEAVAGE OF ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDE THEREOF AS WELL AS A POLYPEPTIDE CONTAINING AN ADDITIVE, USE OF SAME AS WELL AS A PROCESS 审中-公开用于ZEARALENONE和/或ZEARALENONE衍生物的水解溶剂的多肽，其分离的多核苷酸作为包含添加剂的多肽，使用相同方式作为过程公开(公告)号：US20160345606A1
公开(公告)日：2016-12-01
申请号：US14914671
申请日：2014-08-27
Applicant: ERBER AKTIENGESELLSCHAFT
Inventor： Sebastian FRUHAUF , Michaela THAMHESL , Martin PFEFFER , Dieter MOLL , Gerd SCHATZMAYR , Eva Maria BINDER
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , A23V2002/00 , C12N9/14 , C12N9/18 , C12Y301/01 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
Abstract translation: 本发明涉及一种用于玉米赤霉烯酮和/或至少一种玉米赤霉烯酮衍生物的水解切割的多肽，所述多肽是具有选自SEQ ID NO：1-15或其功能变体的氨基酸序列的水解酶， 其中所述功能变体的序列与所述氨基酸序列中的至少一个至少40％相同。 本发明还涉及：含有该多肽的添加剂; 编码多肽的分离的多核苷酸; 以及使用该多肽水解切割玉米赤霉烯酮和/或至少一种玉米赤霉烯酮衍生物的方法。
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公开(公告)号：US20160319258A1
公开(公告)日：2016-11-03
申请号：US15054232
申请日：2016-02-26
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian FRUHAUF , Michaela THAMHESL , Martin PFEFFER , Dieter MOLL , Gerd SCHATZMAYR , Eva Maria BINDER
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , A23V2002/00 , C12N9/14 , C12N9/18 , C12Y301/01 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US20220202045A1
公开(公告)日：2022-06-30
申请号：US17555731
申请日：2021-12-20
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian FRUHAUF , Michaela THAMHESL , Martin PFEFFER , Dieter MOLL , Gerd SCHATZMAYR , Eva Maria BINDER
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US20210338758A1
公开(公告)日：2021-11-04
申请号：US17376727
申请日：2021-07-15
Applicant: Erber Aktiengesellschaft
Inventor： Elisabeth MAYER , Barbara NOVAK , Christina SCHWAB-ANDICS , Ursula HOFSTATTER-SCHAEHS , Gerd SCHATZMAYR
IPC: A61K36/484 , A23K20/163 , A23K10/30 , A61K31/704
Abstract: The use of at least one Glycyrrhiza plant preparation selected from the group of flour of a whole, dried Glycyrrhiza plant, flour of the leaves of the dried Glycyrrhiza plant, flour of roots of the dried Glycyrrhiza plant, aqueous dry extract of the Glycyrrhiza plant, aqueous/ethanolic dry extract of the Glycyrrhiza plant, aqueous extract of the Glycyrrhiza plant, optionally together with at least one excipient, for reducing the toxic effect of at least one polypeptide fungitoxin in agrarian products.
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公开(公告)号：US20190124948A1
公开(公告)日：2019-05-02
申请号：US16161266
申请日：2018-10-16
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian FRUHAUF , Michaela THAMHESL , Martin PFEFFER , Dieter MOLL , Gerd SCHATZMAYR , Eva Maria BINDER
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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