公开(公告)号：US11478418B2

公开(公告)日：2022-10-25

申请号：US16082670

申请日：2017-03-07

Applicant: ISP INVESTMENTS LLC

Inventor： Corinne Coquet

IPC: A61K8/92 ,  A61K8/9789 ,  A61K8/37 ,  A61K8/66 ,  A61Q19/08 ,  C11B15/00 ,  A61K8/97

Abstract: The invention relates to a method for obtaining the water-insoluble fraction of Carica papaya sap, enriched with Carica papaya lipase, the water-insoluble fraction obtainable by this method, a method for the preparation of an activated fat and/or an activated wax by means of said water-insoluble fraction of the Carica papaya sap, the activated fat and/or the activated wax capable of being obtained by this method, a composition combining said activated fat and/or said activated wax, as well as the cosmetic use of these products.

公开(公告)号：US11248224B2

公开(公告)日：2022-02-15

申请号：US16612365

申请日：2018-04-27

Applicant: ISP Investments LLC

Inventor： Elodie Oger ,  Jean-Marie Botto

IPC: C12N5/10 ,  A61K8/9789 ,  C12N15/10 ,  A61Q19/08 ,  A61Q5/00 ,  A61Q19/00

Abstract: The invention relates to a method for obtaining an aqueous extract of Anethum graveolens, enriched with small RNAs having a maximum length of 150 nucleotides, from a plant material, said method comprising the following steps: a) aerial parts of dill is brought into contact with water; b) tetrasodium ethylenediaminetetraacetic acid (EDTA) is added at a pH of between 10.5 and 11; c) the pH of the mixture obtained in b) is then adjusted to a value of between 6 and 8; d) the mixture obtained in c) is purified; and e) the pH is checked and readjusted if necessary to a value of between 6 and 8. The invention also relates to an aqueous extract of Anethum graveolens, enriched with small RNAs having a maximum length of 150 nucleotides, obtained by the method.

公开(公告)号：US11247077B2

公开(公告)日：2022-02-15

申请号：US15773880

申请日：2016-11-04

Applicant: ISP INVESTMENTS LLC ,  LVMH RECHERCHE

Inventor： Valérie Lequoy ,  Frédérique Portolan ,  Audrey Le Mestr ,  Christophe Capallere ,  Isabelle Imbert ,  Joël Mantelin ,  Jean Marie Botto ,  Nouha Domloge ,  Noëlle Garcia ,  Carine Nizard ,  Laurine Bergeron

IPC: A61K36/00 ,  A61K36/63 ,  A61Q19/08 ,  A61K8/9728 ,  A61K8/9717 ,  A61K8/9789

Abstract: The present invention relates to a synergistic extract of Palmaria palmata and of jasmine flower heads, obtained after aqueous extraction of Palmaria palmata, in which maceration of the jasmine flower heads is then carried out, the ratio of the dry weight of Palmaria palmata to the dry weight of the flower heads being between 40/60 and 95/5.
The present invention also relates to a method for obtaining said synergistic extract and cosmetic compositions comprising said extract as an active agent.
The invention finally relates to the cosmetic use of said composition for combating the signs of aging and for improving the elasticity of the skin, by favoring maintenance of the “stem” character of the adult dermal stem cells (SKPs).

公开(公告)号：US20210275939A1

公开(公告)日：2021-09-09

申请号：US16484784

申请日：2018-02-06

Applicant: ISP Investments LLC ,  JAFER ENTERPRISES R&D, S.L. (SOCIEDAD UNIPERSONAL)

Inventor： Anne CLAY ,  Nouha DOMLOGE ,  Isabelle IMBERT ,  Karine CUCUMEL ,  Esmeralda CICCHETTI ,  Ludivine MUR ,  GARNIER Sébastien ,  Leslie DUROURE

IPC: B01D11/02 ,  A61K8/9789 ,  A61Q19/08 ,  A61K8/63

Abstract: The invention relates to a method for obtaining a Marsdenia cundurango extract containing terpinyl cinnamate compounds, the Marsdenia cundurango bark or wood extracts comprising terpinyl cinnamate compounds obtained by the method, cosmetic compositions comprising them, and the cosmetic uses of same for improving the barrier function of the skin, for improving protection against toxins and detoxification of the skin, and finally for reducing the signs of ageing.

公开(公告)号：US20210270978A1

公开(公告)日：2021-09-02

申请号：US17255210

申请日：2019-06-28

Applicant: ISP Investments LLC

Inventor： Rob CROHN ,  Shih HSIAO-YI

IPC: G01T1/08

Abstract: This present disclosure provides a multi-ply radiation dosage indicator, which includes a first ply having two visible readable indicia thereon. The dual radiation sensitive zones are capable of changing opacity in response to exposure radiation. Each radiation sensitive zone can respond to an irradiation dose in tandem or independent of one another. Once the radiation sensitive zone exceeds the design exposure threshold, the visibility of the indicia is altered thereby providing an indication of irradiation exposure. The radiation sensitive zone may either be transparent or opaque and can change its opacity in response to exposure to radiation exceeding a predetermined threshold so as to change the visibility of the indicia.

公开(公告)号：US20210205393A1

公开(公告)日：2021-07-08

申请号：US17208700

申请日：2021-03-22

Applicant: ISP INVESTMENTS LLC

Inventor： Michael KOGANOV ,  Olga DUEVA-KOGANOV ,  Artyom DUEV ,  Steven MICCERI

IPC: A61K36/73 ,  A61K36/752 ,  A61K36/81 ,  A61K36/88 ,  A61K36/185 ,  A61K36/45 ,  A61K36/736

Abstract: The present invention relates to composition comprising a bioactive fractions (ingredients) derived from fruit juice of an Apple (Pyrus malus) produced by processing the fresh fruit of apple under conditions effective to yield a bioactive fraction that is substantially free of protein and patulin. The present invention also relates to compositions having antioxidant and free radical scavenging properties and suitable for topical applications, oral applications and functional drink applications.

公开(公告)号：US11045669B2

公开(公告)日：2021-06-29

申请号：US15564537

申请日：2016-04-05

Applicant: ISP INVESTMENTS LLC ,  JAFER

Inventor： Isabelle Imbert ,  Nouha Domloge ,  Jean Marie Botto ,  Rémi Laville ,  Sébastien Garnier

IPC: A61K36/00 ,  A61Q17/00 ,  A61Q19/08 ,  A61K8/9789 ,  A61K8/9783

Abstract: The invention relates to a hydroalcoholic extract of the aerial parts of Schinus molle. The invention is characterised in that it comprises predominantly quercitrin and miquelianin among the extracted polyphenols, in a concentration, respectively, of at least 0.04% of quercitrin by weight of the total weight of the extract, and of at least 0.02% of miquelianin by weight of the total weight of the extract, the other extracted polyphenols, considered independently of one another, being present in trace form. The invention also relates to a method for preparing an extract of Schinus molle according to the invention and to cosmetic compositions comprising an effective amount of the extract according to the invention as protective active agent, and the cosmetic use of such compositions to improve the barrier function of the skin and to protect the skin against atmospheric pollutants.

公开(公告)号：US10765617B2

公开(公告)日：2020-09-08

申请号：US15772686

申请日：2016-11-21

Applicant: ISP INVESTMENTS LLC

Inventor： Amna Khatun ,  David Petty ,  Lidia Kulcsar

IPC: A61Q5/02 ,  A61Q5/06 ,  A61K8/81 ,  C08F220/18 ,  C08F226/10 ,  A61Q5/12 ,  A61Q1/02

Abstract: Disclosed herein is a personal care conditioning and/or styling composition for keratin substrate comprising: (A) at least one conditioning and/or styling copolymer obtained from polymerizing: (i) about 0.1 wt. % to 99.9 wt. % of at least one cationic or pseudo-cationic monomer selected from the group consisting of acrylamidopropyl trimethylammonium chloride (APT AC) and/or diallyl dimethyl ammonium chloride (DADMAC); and (ii) about 0.1 wt. % to 99.9 wt. % of at least one monomer comprising at least one functionalized or unfunctionalized acryloyl moiety and at least one lactam moiety; (B) at least one cosmetically acceptable excipient; and (C) optionally, at least one effective amount of personal care active ingredient. Also disclose is a process for preparing such composition and method of use thereof.

公开(公告)号：US10351523B2

公开(公告)日：2019-07-16

申请号：US15840995

申请日：2017-12-13

Applicant: ISP INVESTMENTS LLC

Inventor： Krishnamurthy Nacharaju ,  Christophe Buron ,  Christopher J. Toney ,  Michael A. Tallon

IPC: A61K8/42 ,  C07C311/29 ,  C07C237/32 ,  C07C49/84 ,  A61K8/35 ,  A61K8/41 ,  A61K8/46 ,  A61Q17/04

Abstract: UV-absorbing compounds are provided that have at least one reactive hydrogen. These compounds have structures: wherein the generic notations have meanings as described herein. Also provided are formulations comprising a UV-absorbing compounds.

公开(公告)号：US20190201321A1

公开(公告)日：2019-07-04

申请号：US16330020

申请日：2017-09-06

Applicant: ISP Investments LLC ,  ELC Management LLC

Inventor： Nadine PERNODET ,  Dawn LAYMAN ,  Jean-Marie BOTTO ,  Elodie OGER ,  Audrey LE MESTR ,  Isabelle IMBERT ,  Nouha DOMLOGE

IPC: A61K8/9789 ,  A61Q19/08 ,  A61Q17/04

Abstract: The present invention provides a process for obtaining an extract from peach flower extract (Primus persica L.) for skin cosmetic use, a peach flower extract obtainable by the process and a cosmetic composition comprising the said extract. The invention further provides a method for modulating the SIRT2 expression, a method of treatment designed to reduce and/or correct the signs of aging and photo-aging of the skin and keratinous appendages, and to protect the skin against aggressions due to ultraviolet radiation.