公开(公告)号：US20210205393A1

公开(公告)日：2021-07-08

申请号：US17208700

申请日：2021-03-22

Applicant: ISP INVESTMENTS LLC

Inventor： Michael KOGANOV ,  Olga DUEVA-KOGANOV ,  Artyom DUEV ,  Steven MICCERI

IPC: A61K36/73 ,  A61K36/752 ,  A61K36/81 ,  A61K36/88 ,  A61K36/185 ,  A61K36/45 ,  A61K36/736

Abstract: The present invention relates to composition comprising a bioactive fractions (ingredients) derived from fruit juice of an Apple (Pyrus malus) produced by processing the fresh fruit of apple under conditions effective to yield a bioactive fraction that is substantially free of protein and patulin. The present invention also relates to compositions having antioxidant and free radical scavenging properties and suitable for topical applications, oral applications and functional drink applications.

公开(公告)号：US20190021984A1

公开(公告)日：2019-01-24

申请号：US16070391

申请日：2017-01-16

Applicant: ISP INVESTMENTS LLC

Inventor： Michael KOGANOV ,  Olga DUEVA-KOGANOV ,  Paul RECHT ,  Artyom DUEV ,  Li ZHANG ,  Steven MICCERI ,  Robert TURNER

IPC: A61K8/9789 ,  A61K36/258

Abstract: The present invention relates to bioactive compositions (including, for example, bioactive serum fractions and bioactive extracts) derived from ginseng (Panax spp.) fresh whole plant, a particular part of the plant (e.g., rhizome, roots, leaves, stems, flowers, fruit) or any combination of these plant parts. The bioactive serum fractions and bioactive extracts are free of or substantially free of pulegone and/or free of or substantially free of proteins. The present invention also provides products comprising the bioactive serum fractions and/or bioactive extracts. The present invention further provides methods of making and using the bioactive serum fractions and/or bioactive extracts. Further, the bioactive serum fractions and bioactive extracts have anti-inflammatory and/or anti-irritant and/or anti-aging activities.

公开(公告)号：US20170340556A1

公开(公告)日：2017-11-30

申请号：US15679100

申请日：2017-08-16

Applicant: ISP INVESTMENTS LLC

Inventor： Michael KOGANOV ,  Olga DUEVA-KOGANOV

IPC: A61K8/97 ,  A61Q19/02 ,  A61K36/48

CPC classification number: A61K8/97 ,  A61K36/48 ,  A61Q19/02

Abstract: The present invention relates to compositions comprising banyan tree, lotus, and clover serum fractions. A method of improving the appearance of a hyperpigmented spot may comprise the step of applying a composition comprising an effective amount of banyan tree serum fraction, lotus serum fraction, and clover serum fraction to a hyperpigmented spot on a skin surface, wherein the composition is applied for a period of time sufficient to improve the appearance of the hyperpigmented spot. The method may include the step of identifying a hyperpigmented spot on a facial skin surface. Other methods as disclosed include a method for improving the appearance of post-inflammatory hyperpigmentation.

公开(公告)号：US20220347082A1

公开(公告)日：2022-11-03

申请号：US17627524

申请日：2020-07-14

Applicant: ISP INVESTMENTS LLC ,  THE BURT'S BEES PRODUCTS COMPANY

Inventor： Michael KOGANOV ,  Olga DUEVA-KOGANOV ,  Arytom DUEV ,  Li ZHANG ,  Paul RECHT ,  Steven MICCERI ,  Abena Agyeiwaa ANTWI ,  Hemali GUNT

IPC: A61K8/9789 ,  A61Q19/08 ,  A61Q17/04 ,  A61K8/34 ,  A61K8/37

Abstract: The present invention is related to a skin care composition comprising (1) a physiologically acceptable medium and (2) a synergistic composition consisting of: a blend of a Nelumbo nucifera (Sacred Lotus) serum fraction and a Camellia sinensis (Tea) serum fraction in a respective weight ratio of 75:25; or a blend of a Nelumbo nucifera (Sacred Lotus) serum fraction and a Chamomilla recutita (German chamomile) serum fraction in a respective weight ratio of 75:25. The invention also relates to a method for improving skin appearance associated with skin aging comprising applying compositions thereof.

公开(公告)号：US20190231838A1

公开(公告)日：2019-08-01

申请号：US16376953

申请日：2019-04-05

Applicant: ISP INVESTMENTS LLC

Inventor： Michael KOGANOV ,  Olga Dueva-Koganov ,  Artyom Duev ,  Steven Micceri

IPC: A61K36/73 ,  A61K36/752 ,  A61K36/736 ,  A61K36/81 ,  A61K36/185 ,  A61K36/88 ,  A61K36/45

CPC classification number: A61K36/73 ,  A61K36/185 ,  A61K36/45 ,  A61K36/736 ,  A61K36/752 ,  A61K36/81 ,  A61K36/88 ,  A61K2236/31 ,  A61K2236/37

Abstract: The present invention relates to bioactive fractions (ingredients) derived from fruit juices. The bioactive fractions are either free of or substantially free of patulin and protein. Further, the bioactive fractions have antioxidant, free radical scavenging, moisturizing and buffering properties. The present invention also relates to a method for isolating bioactive fractions that are derived from fruit juices and are free or substantially free of protein and patulin. The present invention also relates to a method for preparing a bioactive fractions derived from fruit juices that are stabilized and are either free of or substantially free of patulin and protein.

公开(公告)号：US20190201320A1

公开(公告)日：2019-07-04

申请号：US16325536

申请日：2017-09-06

Applicant: ISP Investments LLC

Inventor： Karine CUCUMEL ,  Isabelle IMBERT ,  Nouha DOMLOGE ,  Olga DUEVA-KOGANOV ,  Michael KOGANOV

IPC: A61K8/9789 ,  A61Q19/06 ,  A61Q19/00

CPC classification number: A61K8/9789 ,  A61K8/97 ,  A61Q19/00 ,  A61Q19/06 ,  A61Q90/00

Abstract: The present invention is related to a cosmetic method for promoting lipolysis, slimming, draining, smooth skin surface, reducing the volume of localized fat deposits, the method including applying a topical composition comprising a Nelumbo nucifera (Lotus) Extract.

公开(公告)号：US20170360691A1

公开(公告)日：2017-12-21

申请号：US15691708

申请日：2017-08-30

Applicant: ISP INVESTMENTS LLC

Inventor： Olga V. DUEVA-KOGANOV ,  Michael KOGANOV ,  Jeanette RICHARDS ,  Tom DAWSON ,  Mary Jane COMBS

IPC: A61K8/97 ,  A61Q5/00 ,  A61Q19/08

CPC classification number: A61K8/97 ,  A61K8/9789 ,  A61K2800/522 ,  A61K2800/5922 ,  A61Q5/00 ,  A61Q5/002 ,  A61Q19/08

Abstract: A bioactive composition and method of using the composition is provided having anti-aging, antioxidant and/or free radical scavenging properties.

公开(公告)号：US20250049698A1

公开(公告)日：2025-02-13

申请号：US18720432

申请日：2022-12-14

Applicant: ISP INVESTMENTS LLC

Inventor： Michael KOGANOV ,  Olga DUEVA-KOGANOV ,  Artyom DUEV ,  Li ZHANG ,  Paul RECHT ,  Steven MICCERI

IPC: A61K8/9789 ,  A61Q19/08

Abstract: The present invention relates to a method for obtaining a bioactive serum fraction derived from fresh rose flowers (Rosa spp.).
The present invention also provides bioactive serum fractions and bioactive extracts derived from fresh rose flowers (Rosa spp.) and compositions comprising the same.
The present invention further relates to a method of cosmetic treatment for improving skin appearance associated with antioxidant and antiaging properties of the bioactive serum fraction and the bioactive extract derived from fresh rose flowers (Rosa spp.).