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公开(公告)号:US20110230406A1
公开(公告)日:2011-09-22
申请号:US13044607
申请日:2011-03-10
申请人: John Kehoe , Daphne A. Salick , Carrie H. Fang , Chunlin Yang , Abla Creasey
发明人: John Kehoe , Daphne A. Salick , Carrie H. Fang , Chunlin Yang , Abla Creasey
CPC分类号: B82Y5/00 , A61K47/6435 , A61K47/66 , C07K7/08
摘要: We have disclosed affinity peptides toward BMP-2. More specifically we have disclosed an affinity biomatrix where the affinity peptide is covalently attached to a biocompatible, biodegradable polymer. The affinity biomatrix is useful in preparing controlled release devices for BMP-2.
摘要翻译: 我们已经公开了针对BMP-2的亲和肽。 更具体地,我们已经公开了一种亲和力生物基质,其中亲和肽共价连接到生物相容的可生物降解的聚合物上。 亲和力生物基质可用于制备BMP-2的受控释放装置。
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公开(公告)号:US20100151003A1
公开(公告)日:2010-06-17
申请号:US12514622
申请日:2007-12-20
申请人: Mohit Trikha , Wang Bryan , Frank Shi , John Kehoe
发明人: Mohit Trikha , Wang Bryan , Frank Shi , John Kehoe
IPC分类号: A61K9/127 , C07K2/00 , C07K7/06 , C07K7/08 , C07H21/00 , C07K16/00 , A61K38/02 , A61P35/00 , A61P31/12
摘要: Short oligopeptides are provided which are capable of binding to the epidermal growth factor receptor on the surface of human tumor cells. Methods for using the peptides as targeting moieties in more complex compositions, such as conjugates of cytoxins, and/or structures, such as liposomal structures, for the purposes of drug delivery are also provided.
摘要翻译: 提供能够结合人肿瘤细胞表面的表皮生长因子受体的短寡肽。 还提供了用于在更复杂的组合物中使用肽作为靶向部分的方法,例如用于药物递送目的的细胞毒素和/或结构(例如脂质体结构)的缀合物。
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公开(公告)号:US2369300A
公开(公告)日:1945-02-13
申请号:US49517243
申请日:1943-07-17
申请人: JOHN KEHOE JOSEPH
发明人: JOHN KEHOE JOSEPH
IPC分类号: H01F7/02
CPC分类号: H01F7/0226
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