公开(公告)号：US20140161727A1

公开(公告)日：2014-06-12

申请号：US13885126

申请日：2011-11-18

Applicant: BIOLEADERS CORPORATION ,  KOOKMIN UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  THE INDUSTRY AND ACADEMIC IN CHUNGNAM NATIONAL UNIVERSITY

Inventor： Moon-Hee Sung ,  Yong Taik Lim ,  Young-Woock Noh ,  II Han Lee

IPC: A61K49/00

CPC classification number: A61K49/0054 ,  A61K49/0034 ,  A61K49/0056 ,  G01N21/6428 ,  G01N21/6456

Abstract: The present invention relates to an optical imaging probe for detecting a sentinel lymph node, which contains a complex of poly-gamma-glutamic acid and an optical imaging dye, and more particularly to an optical imaging probe for detecting a sentinel lymph node, which contains a poly-gamma-glutamic acid/optical imaging dye complex that, when injected subcutaneously in vivo, remains in the sentinel lymph node for a relatively long period of time and has a low tendency to migrate to other lymph nodes. The present invention provides a poly-gamma-glutamic acid/fluorescent dye complex, which contains no radiopharmaceutical and is harmless to the human body. The use of the poly-gamma-glutamic acid/fluorescent dye complex makes it possible to accurately detect the position of a sentinel lymph node in real time without concerns about radioactive contamination.

Abstract translation: 本发明涉及一种用于检测前哨淋巴结的光学成像探针，其包含聚-γ-谷氨酸和光学成像染料的复合物，更具体地涉及用于检测前哨淋巴结的光学成像探针，其包含 聚γ-谷氨酸/光学成像染料复合物，其在体内皮下注射时保留在前哨淋巴结相当长的一段时间内，并且具有低迁移到其他淋巴结的倾向。 本发明提供了不含放射性药剂且对人体无害的聚-γ-谷氨酸/荧光染料复合体。 使用聚-γ-谷氨酸/荧光染料复合物可以实时准确地检测前哨淋巴结的位置，而不用担心放射性污染。

公开(公告)号：US09600541B2

公开(公告)日：2017-03-21

申请号：US14616633

申请日：2015-02-06

Applicant: KOOKMIN UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Eun Mi Choi ,  Won Hee Cho

IPC: G01M17/00 ,  G06F7/00 ,  G06F11/30 ,  G06F19/00 ,  G07C5/00 ,  G06F17/30 ,  G06Q40/08

CPC classification number: G06F17/30539 ,  G06Q40/08 ,  G07C5/008

Abstract: Provided is a method of processing and analyzing vehicle driving big data, the method including: refining vehicle driving data of raw data; acquiring statistical data based on the refined vehicle driving data; and performing mining analysis based on at least one of the refined vehicle driving data and the acquired statistical data.

公开(公告)号：US09915782B2

公开(公告)日：2018-03-13

申请号：US15355293

申请日：2016-11-18

Applicant: KOOKMIN UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Donghwan Ahn ,  Yoonyoung Bae

IPC: G02B6/12 ,  G02B6/14 ,  G02B6/122 ,  G02F1/025 ,  G02F1/015

CPC classification number: G02B6/14 ,  G02B6/1228 ,  G02B2006/12061 ,  G02B2006/12152 ,  G02F1/025 ,  G02F2001/0151

Abstract: An optical interconnection device including: a first element layer formed on a substrate; a second element layer disposed on the first element layer and receiving an optical signal; and a mode converter interposed between the first element layer and the second element layer, and eliminating a difference between an effective refractive index of the first element layer and an effective refractive index of the second element layer and match a mode profile, wherein the first element layer, the mode converter, and the second element layer are sequentially disposed on respective planes spaced apart from each other on the substrate, and one end of the mode converter overlaps a part of the second element layer, and the other end of the mode converter overlaps a part of the first element layer.