-
公开(公告)号：US12211899B2
公开(公告)日：2025-01-28
申请号：US17583206
申请日：2022-01-25
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyung-jun Kim , Seung Hwan Kim
Abstract: Embodiments relate to a semiconductor device, which includes: a substrate made of a first material; an insulating layer formed on an upper surface of the substrate; a trench formed at the insulating layer to penetrate the insulating layer toward the substrate; and a seed layer disposed in the trench. The seed layer is made of a second material, the second material lattice-mismatches with respect to the first material, the seed layer includes a threading dislocation extending at least partially in a first direction non-parallel to the upper surface of the substrate and parallel to a direction of a (111) plane and a threading dislocation extending at least partially in a second direction, and the extension of the threading dislocation is terminated at a sidewall of the trench.
-
公开(公告)号：US20250026102A1
公开(公告)日：2025-01-23
申请号：US18467610
申请日：2023-09-14
Applicant: Korea Institute of Science and Technology
Inventor： Seungjun CHUNG , Jun Chan CHOI , Hoon Yeub JEONG , Phillip LEE , Jeong Gon SON , Heesuk KIM
Abstract: Provided is a method of manufacturing a stretchable substrate having improved thickness deformation uniformity through control of a spatial crosslinking degree according to various embodiments of the present disclosure to implement the above object. The method includes forming a substrate part of an elastic material, forming an auxetic including a plurality of unit structures on the substrate part, and forming a fixing part on the substrate part on which the auxetic is formed, wherein the fixing part has a different vertical crosslinking density at each position.
-
公开(公告)号：US20250026101A1
公开(公告)日：2025-01-23
申请号：US18467594
申请日：2023-09-14
Applicant: Korea Institute of Science and Technology
Inventor： Seungjun CHUNG , Jun Chan CHOI , Hoon Yeub JEONG , Jeong Gon SON , Heesuk KIM , Phillip LEE
Abstract: Provided is a method of manufacturing a stretchable substrate having improved stretching deformation uniformity through control of a spatial crosslinking degree according to various embodiments of the present disclosure to implement the above object. The method includes forming a substrate part of an elastic material, forming an auxetic including a plurality of unit structures on the substrate part, and forming a fixing part on the substrate part on which the auxetic is formed, wherein the fixing part has a different crosslinking density in each region.
-
公开(公告)号：US20250019705A1
公开(公告)日：2025-01-16
申请号：US18745018
申请日：2024-06-17
Inventor： Ju Hee RYU , Ick Chan KWON , Youngji KO , Thomas M. ROBERTS , Jean J. ZHAO , Liya DING
IPC: C12N15/113 , A61K45/06 , A61K47/64 , A61K47/65 , A61P35/00
Abstract: Provided is BRCA-specific siRNA for enhancing the sensitivity of cancer cells to PARP inhibitors. According to the present disclosure, the siRNA can induce cancer cell death together with the PARP inhibitors in patients with wild-type BRCA genes with a low therapeutic effect of the PARP inhibitors, and the fusion protein-siRNA complex for siRNA delivery is up-taken into cells via CD47, and thus more specifically delivered to cancer cells while up-taken with high efficiency, thereby maximizing a desired cell death effect.
-
15.发明授权公开(公告)号：US12186318B2
公开(公告)日：2025-01-07
申请号：US17083895
申请日：2020-10-29
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyung Jun Ahn
IPC: A61K31/517 , A61K31/337 , A61K31/404 , C12N15/113 , A61K45/06
Abstract: The present invention relates to a method of treating a cancer including administering a pharmaceutical composition to an individual suspected to have the cancer excluding humans in a pharmaceutically effective amount, where the pharmaceutical composition comprises an agent capable of inhibiting expression of kinesin spindle protein (KSP) and a mitosis inhibitor.
-
Patent Agency Ranking
公开(公告)号：US12173342B2
公开(公告)日：2024-12-24
申请号：US17630657
申请日：2020-08-26
Inventor： Chan Kyu Lee , Da Hui Ha , Choon Geun Lee , Ye Ram Lee , Hak Suk Chung
IPC: C12P19/44
Abstract: Provided is a method of producing monophosphoryl lipid A (MPLA). According to the method, MPLA may be produced with high purity and high purity by using a bacterium producing MPLA.
-
公开(公告)号：US20240417581A1
公开(公告)日：2024-12-19
申请号：US18408448
申请日：2024-01-09
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Seon Joon KIM , Seung Sang HWANG , Albert LEE , Taegon OH , Tae Yun KO , Junpyo HONG
IPC: C09D11/52 , C01B32/907 , C09D11/033 , C09D11/037 , H05K9/00
Abstract: Disclosed in the present specification are a two-dimensional MXene surface-modified with a metal-organic network, a method of preparing the same, a MXene organic ink containing the same, and uses (e.g., an electromagnetic wave shielding material). In one aspect, the two-dimensional MXene surface-modified with a metal-organic network according to the present invention can use various organic ligands by linking the surface with the organic through the metal, and can be stably dispersed in various organic solvents, especially in industrial non-polar organic solvents as well as polar organic solvents, thereby being applied to a more general-purpose technologies, and securing stability against chemical oxidation to improve long-term stability.
-
公开(公告)号：US12158686B2
公开(公告)日：2024-12-03
申请号：US17956337
申请日：2022-09-29
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Kayoung Kim , Chulki Kim , Jae Hun Kim , Taikjin Lee , Sang Wook Han , Seungwoo Jeon , Yu Kyeong Kim , Young Tae Byun
Abstract: One aspect of the present disclosure is a method for selective surface functionalization using a single-photon source. The method for selective functionalization using a single-photon source includes: (a) adding a single-photon source to a solution containing a photosensitizer and a monomer; and (b) emitting a single photon from the single-photon source. One aspect of the present disclosure is a selectively functionalized single-photon source prepared by the method.
-
公开(公告)号：US20240392422A1
公开(公告)日：2024-11-28
申请号：US18232456
申请日：2023-08-10
Inventor： Dong Hwi Kim , Soon Woo Kwon , Sang Jae Yoon , Min Woo Kang , Chung An Lee , Seung Hyun Hong , Hyun Ki Kim , Dong Ik Kim , Jae Hyeok Shim , Woo Sang Jung , Dong Jun Choi
IPC: C22C38/44 , C21D8/02 , C22C38/00 , C22C38/02 , C22C38/04 , C22C38/06 , C23C8/18 , C23C8/26 , C23C28/04
Abstract: A bearing steel has improved insulation performance by forming a continuous insulating film. The bearing steel includes 0.65 to 1.0 mass % of carbon (C), 1.6 to 2.0 mass % of chromium (Cr), 1.5 to 3.0 mass % of aluminum (Al), 0.8 to 1.2 mass % of manganese (Mn), 0.7 to 1.0 mass % of silicon (Si), 0.1 to 0.3 mass % of nickel (Ni), 0.08 to 0.12 mass % of molybdenum (Mo), and a balance of iron (Fe), in which an oxynitride layer including a nitride layer and an oxide layer is formed on the surface of a material.
-
公开(公告)号：US20240374245A1
公开(公告)日：2024-11-14
申请号：US18649418
申请日：2024-04-29
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sunghwan LIM , Sangseo JEON , Hyehyun HAN
IPC: A61B10/00 , A61B5/107 , A61B34/10 , A61B34/20 , G06T3/40 , G06T7/00 , G06T7/11 , G06T7/20 , G06T7/30 , G06T7/50 , G06T17/00
Abstract: A method for a breast biopsy based on indirect magnetic resonance imaging (MRI) guidance of present disclosure, may comprises obtaining a breast MRI data of a patient, generating a deformable breast model using the breast MRI data, measuring real-time breast shape of the patient using a depth sensor, performing a real-time deformable registration using the deformable breast model and the real-time shape data, estimating movements of the MRI targets inside of the breast, performing a breast biopsy for the MRI targets.
-
-
-
-
-
-
-
-
-
Search Results
2699
records
(took 0.044 seconds)
