公开(公告)号：US20100077613A1

公开(公告)日：2010-04-01

申请号：US12566598

申请日：2009-09-24

申请人： Hiroyuki Kamikura ,  Hiroshige Owaki ,  Kazuhide Nakamura

发明人： Hiroyuki Kamikura ,  Hiroshige Owaki ,  Kazuhide Nakamura

IPC分类号： B23P17/00

CPC分类号： B41J2/161 ,  B41J2/1623 ,  B41J2/1637 ,  B41J2/17563 ,  B41J2002/14362 ,  Y10T29/49146 ,  Y10T29/49158 ,  Y10T29/49401

摘要： A method for manufacturing a liquid ejecting head is provided. The liquid ejecting head has nozzle openings and ejects liquid supplied through a liquid supply passage from the nozzle openings. The manufacturing method includes: disposing a filtering member between a first supply member and a second supply member, the first supply member having one part of the liquid supply passage formed therein, the second supply member having the other part or another part of the liquid supply passage formed therein, the second supply member being disposed over one surface of the first supply member; and injecting a resin material over the one surface of the first supply member to cover a part of the second supply member for molding a fixation member and fixing the first supply member and the second supply member into a single-piece member as a result of the molding, wherein a convex is formed on a surface of the fixation member in the mold fixation of the first supply member and the second supply member, and a concave is formed in the surface of the fixation member in the mold fixation of the first supply member and the second supply member.

摘要翻译： 提供一种液体喷射头的制造方法。 液体喷射头具有喷嘴开口，并从喷嘴开口排出通过液体供给通道供给的液体。 制造方法包括：在第一供给部件和第二供给部件之间设置过滤部件，第一供给部件具有形成在其中的供液通路的一部分，第二供给部件具有液体供给部的另一部分或另一部分 通道，其中第二供应构件设置在第一供应构件的一个表面上; 并且在所述第一供应构件的一个表面上注入树脂材料以覆盖所述第二供应构件的用于模制固定构件的部分，并且将所述第一供应构件和所述第二供应构件固定为单件构件，作为所述第一供应构件 模制，其中在第一供给构件和第二供给构件的模具固定中在固定构件的表面上形成凸起，并且在第一供给构件的模具固定中在固定构件的表面中形成凹部 和第二供应构件。

公开(公告)号：US20080312221A1

公开(公告)日：2008-12-18

申请号：US12175361

申请日：2008-07-17

申请人： Yasunari Fujiwara ,  Terufumi Senga ,  Tsuyoshi Nishitoba ,  Tatsushi Osawa ,  Atsushi Miwa ,  Kazuhide Nakamura

发明人： Yasunari Fujiwara ,  Terufumi Senga ,  Tsuyoshi Nishitoba ,  Tatsushi Osawa ,  Atsushi Miwa ,  Kazuhide Nakamura

IPC分类号： A61K31/47 ,  C07D215/233 ,  C07D413/12 ,  A61K31/541 ,  A61P35/00 ,  A61K31/5377 ,  C07D417/12

CPC分类号： C07D215/233 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/517 ,  A61K31/5377 ,  C07D215/40 ,  C07D239/88 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12

摘要： An objective of the present invention is to provide compounds having potent antitumor activity. The compounds of the present invention are represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof: wherein X=CH or N; Z=O or S; L=O or S; M=CR10R11, wherein R10 and R11=H, alkyl, or alkoxy, NR12 wherein R12=H or alkyl; R1, R2, and R3=H or optionally substituted alkoxy; R4=H; R5-8=H, halogen, alkoxy or the like; and R9=alkyl optionally substituted by —R14, -T-R15, or —NR16R17 wherein T=O, S, or NH; R14=an optionally substituted carbocyclic or heterocyclic ring; and R15-17=alkyl or an optionally substituted carbocyclic or heterocyclic ring, or —NR18R19 wherein R18 and R19=H, optionally substituted alkyl, or an optionally substituted carbocylic or heterocyclic ring, or optionally substituted carbocyclic or heterocyclic ring.

摘要翻译： 本发明的目的是提供具有有效抗肿瘤活性的化合物。 本发明的化合物由式（I）表示或其药学上可接受的盐或溶剂化物：其中X = CH或N; Z = O或S; L = O或S; M = CR10R11，其中R10和R11 = H，烷基或烷氧基，NR12，其中R12 = H或烷基; R1，R2和R3 = H或任选取代的烷氧基; R4 = H; R5-8 = H，卤素，烷氧基等; 并且R 9 =任选被-R 14，-T-R 15或-NR 16 R 17取代的烷基，其中T = O，S或NH; R14 =任选取代的碳环或杂环; 和R 15-17 =烷基或任选取代的碳环或杂环，或-NR 18 R 19，其中R 18和R 19 = H，任选取代的烷基，或任选取代的碳环或杂环，或任选取代的碳环或杂环。

公开(公告)号：US08333014B2

公开(公告)日：2012-12-18

申请号：US12566598

申请日：2009-09-24

申请人： Hiroyuki Kamikura ,  Hiroshige Owaki ,  Kazuhide Nakamura

发明人： Hiroyuki Kamikura ,  Hiroshige Owaki ,  Kazuhide Nakamura

IPC分类号： B21D53/76 ,  B29C45/14

CPC分类号： B41J2/161 ,  B41J2/1623 ,  B41J2/1637 ,  B41J2/17563 ,  B41J2002/14362 ,  Y10T29/49146 ,  Y10T29/49158 ,  Y10T29/49401

摘要： A method for manufacturing a liquid ejecting head is provided. The liquid ejecting head has nozzle openings and ejects liquid supplied through a liquid supply passage from the nozzle openings. The manufacturing method includes: disposing a filtering member between a first supply member and a second supply member, the first supply member having one part of the liquid supply passage formed therein, the second supply member having the other part or another part of the liquid supply passage formed therein, the second supply member being disposed over one surface of the first supply member; and injecting a resin material over the one surface of the first supply member to cover a part of the second supply member for molding a fixation member and fixing the first supply member and the second supply member into a single-piece member as a result of the molding, wherein a convex is formed on a surface of the fixation member in the mold fixation of the first supply member and the second supply member, and a concave is formed in the surface of the fixation member in the mold fixation of the first supply member and the second supply member.

摘要翻译： 提供一种液体喷射头的制造方法。 液体喷射头具有喷嘴开口，并从喷嘴开口排出通过液体供给通道供给的液体。 制造方法包括：在第一供给部件和第二供给部件之间设置过滤部件，第一供给部件具有形成在其中的供液通路的一部分，第二供给部件具有液体供给部的另一部分或另一部分 通道，其中第二供应构件设置在第一供应构件的一个表面上; 并且在所述第一供应构件的一个表面上注入树脂材料以覆盖所述第二供应构件的用于模制固定构件的一部分，并且将所述第一供应构件和所述第二供应构件固定为单件构件，作为所述第一供应构件 模制，其中在所述第一供给构件和所述第二供给构件的模具固定中在所述固定构件的表面上形成凸起，并且在所述第一供给构件的模具固定中在所述固定构件的表面中形成凹部 和第二供应构件。

公开(公告)号：US08329086B2

公开(公告)日：2012-12-11

申请号：US12853171

申请日：2010-08-09

申请人： Hiroyuki Kobayashi ,  Katsuhiro Okubo ,  Kazuhide Nakamura ,  Nobuyoshi Uji

发明人： Hiroyuki Kobayashi ,  Katsuhiro Okubo ,  Kazuhide Nakamura ,  Nobuyoshi Uji

IPC分类号： B29C45/14

CPC分类号： B29C45/14467 ,  B29C45/14836 ,  B29C45/34 ,  B29L2031/14 ,  B29L2031/767

摘要： There is provided a method of manufacturing a liquid ejecting head which includes a head main body having nozzles ejecting a liquid supplied via a liquid supply passage, a first supply member having a first liquid supply passage forming a part of the liquid supply passage, a second supply member disposed on a downstream side of the first supply member and having a second liquid supply passage communicating with the first liquid supply passage and forming a part of the liquid supply passage, a filter disposed between the first and second supply members so as to cross the liquid supply passage, and an integrally molded member fixing the first and second supply members by a resin in a state where the filter is nipped between the first and second supply members. The method includes: forming a supporting protrusion protruding toward the filter and supporting the filter on an inner wall surface of at least one of the first and second supply members; and forming the integrally molded member in the state where the filter is nipped between the first and second supply members and a pressure difference is caused between the first and second supply members on both sides of the filter so that a pressure is lower on the side of the supporting protrusion.

摘要翻译： 提供了一种制造液体喷射头的方法，该喷射头包括：头主体，其具有喷射经由液体供应通道供应的液体的喷嘴;第一供应构件，具有形成液体供应​​通道的一部分的第一液体供应通道， 供给部件配置在第一供给部件的下游侧，具有与第一供液通路连通并形成液体供给通路的一部分的第二液体供给通路，配置在第一供给部件和第二供给部件之间， 液体供应通道，以及在过滤器被夹持在第一和第二供应构件之间的状态下用树脂固定第一和第二供应构件的整体模制件。 该方法包括：形成朝向过滤器突出的支撑突起，并且将过滤器支撑在第一和第二供应构件中的至少一个的内壁表面上; 并且在过滤器被夹持在第一和第二供应构件之间的状态下形成整体模制构件，并且在过滤器的两侧上的第一和第二供应构件之间产生压力差，使得在过滤器的侧面上的压力较低 支撑突起。

公开(公告)号：US20110105747A1

公开(公告)日：2011-05-05

申请号：US12987610

申请日：2011-01-10

申请人： Yasunari FUJIWARA ,  Terufumi Senga ,  Tsuyoshi Nishitoba ,  Tatsushi Osawa ,  Atsushi Niwa ,  Kazuhide Nakamura

发明人： Yasunari FUJIWARA ,  Terufumi Senga ,  Tsuyoshi Nishitoba ,  Tatsushi Osawa ,  Atsushi Niwa ,  Kazuhide Nakamura

IPC分类号： C07D401/12 ,  C07D215/233 ,  C07D413/12 ,  C07D403/12 ,  C07D409/12 ,  C07D417/12

CPC分类号： C07D215/233 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/517 ,  A61K31/5377 ,  C07D215/40 ,  C07D239/88 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12

摘要： An objective of the present invention is to provide compounds having potent antitumor activity. The compounds of the present invention are represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof: wherein X=CH or N; Z=O or S; L=O or S; M=CR10R11, wherein R10 and R11=H, alkyl, or alkoxy, NR12 wherein R12=H or alkyl; R1, R2, and R3=H or optionally substituted alkoxy; R4=H; R5-8=H, halogen, alkoxy or the like; and R9=alkyl optionally substituted by -T-R15, or —NR16R17 wherein T=O, S, or NH; R14=an optionally substituted carbocyclic or heterocyclic ring; and R15-17=alkyl or an optionally substituted carbocyclic or heterocyclic ring, or —NR18R19 wherein R18 and R19=H, optionally substituted alkyl, or an optionally substituted carbocylic or heterocyclic ring, or optionally substituted carbocyclic or heterocyclic ring.

摘要翻译： 本发明的目的是提供具有有效抗肿瘤活性的化合物。 本发明的化合物由式（I）表示或其药学上可接受的盐或溶剂化物：其中X = CH或N; Z = O或S; L = 0或S; M = CR10R11，其中R10和R11 = H，烷基或烷氧基，NR12，其中R12 = H或烷基; R1，R2和R3 = H或任选取代的烷氧基; R4 = H; R5-8 = H，卤素，烷氧基等; 并且R 9 =任选被-T-R 15或-NR 16 R 17取代的烷基，其中T = O，S或NH; R14 =任选取代的碳环或杂环; 和R 15-17 =烷基或任选取代的碳环或杂环，或-NR 18 R 19，其中R 18和R 19 = H，任选取代的烷基，或任选取代的碳环或杂环，或任选取代的碳环或杂环。

公开(公告)号：US20110030216A1

公开(公告)日：2011-02-10

申请号：US12853163

申请日：2010-08-09

申请人： Hiroyuki Kobayashi ,  Katsuhiro Okubo ,  Kazuhide Nakamura ,  Nobuyoshi Uji

发明人： Hiroyuki Kobayashi ,  Katsuhiro Okubo ,  Kazuhide Nakamura ,  Nobuyoshi Uji

IPC分类号： B23P17/00

CPC分类号： B41J2/175 ,  B41J2/17563 ,  Y10T29/49401

摘要： There is provided a method of manufacturing a liquid ejecting head which includes a head main body having nozzles ejecting a liquid supplied via a liquid supply passage, a first supply member having a first liquid supply passage forming a part of the liquid supply passage, a second supply member disposed on a downstream side of the first supply member and having a second liquid supply passage communicating with the first liquid supply passage and forming a part of the liquid supply passage, a filter disposed between the first and second supply members so as to cross the liquid supply passage, and an integrally molded member fixing the first and second supply members by a resin in a state where the filter is nipped between the first and second supply members. The method includes: disposing the filter in one of the first and second supply members; nipping the filter by the first and second supply members in a state where the filter is sucked, adsorbed, and positioned via a suction hole of the first or second supply member; and forming the integrally molded member in the state where the filter is nipped between the first and second supply members.

摘要翻译： 提供了一种制造液体喷射头的方法，该喷射头包括：头主体，其具有喷射经由液体供应通道供应的液体的喷嘴;第一供应构件，具有形成液体供应​​通道的一部分的第一液体供应通道， 供给部件配置在第一供给部件的下游侧，具有与第一供液通路连通并形成液体供给通路的一部分的第二液体供给通路，配置在第一供给部件和第二供给部件之间， 液体供应通道，以及在过滤器被夹持在第一和第二供应构件之间的状态下用树脂固定第一和第二供应构件的整体模制件。 该方法包括：将过滤器设置在第一和第二供应构件之一中; 在过滤器被吸入，吸附和经由第一或第二供应构件的抽吸孔定位的状态下，通过第一和第二供应构件夹持过滤器; 并且在过滤器被夹持在第一和第二供应构件之间的状态下形成一体模制构件。