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11.Production and use of highly functional, highly branched or hyperbranched polylysines 有权
Title translation: 高功能,高支化或超支化聚赖氨酸的生产和使用公开(公告)号:US08846842B2
公开(公告)日:2014-09-30
申请号:US12801343
申请日:2010-06-04
Applicant: Bernd Bruchmann , Harm-Anton Klok , Markus Thomas Scholl
Inventor: Bernd Bruchmann , Harm-Anton Klok , Markus Thomas Scholl
CPC classification number: C07K14/001 , C08G83/005 , Y02P20/55 , Y10S977/754
Abstract: The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use.
Abstract translation: 本发明涉及新的高官能度,高支化或超支化聚赖氨酸,其制备方法及其应用。
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12.BISPECIFIC, BIVALENT ANTI-VEGF/ANTI-ANG-2 ANTIBODIES 有权
Title translation: BISPECIFIC,BIVALENT ANTI-VEGF / ANTI-ANG-2 ANTIBODIES公开(公告)号:US20110236388A1
公开(公告)日:2011-09-29
申请号:US13071127
申请日:2011-03-24
Applicant: Monika Baehner , Sabine Imhof-Jung , Anita Kavlie , Hubert Kettenberger , Christian Klein , Joerg Thomas Regula , Wolfgang Schaefer , Juergen Michael Schanzer , Werner Scheuer , Kay-Gunnar Stubenrauch , Markus Thomas
Inventor: Monika Baehner , Sabine Imhof-Jung , Anita Kavlie , Hubert Kettenberger , Christian Klein , Joerg Thomas Regula , Wolfgang Schaefer , Juergen Michael Schanzer , Werner Scheuer , Kay-Gunnar Stubenrauch , Markus Thomas
IPC: A61K39/395 , C07K16/22 , C07H21/00 , A61P9/00 , A61P35/00 , C12N15/63 , C12P21/02 , C12N5/10 , C12N1/00
CPC classification number: C07K16/22 , A61K2039/505 , C07K16/3015 , C07K16/3046 , C07K16/468 , C07K2317/31 , C07K2317/35 , C07K2317/52 , C07K2317/522 , C07K2317/56 , C07K2317/66 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
Abstract translation: 本发明涉及针对人血管内皮生长因子(VEGF / VEGF-A)和针对人血管生成素-2(ANG-2)的双特异性二价抗体,其生产方法,含有所述抗体的药物组合物及其用途。
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13.PRODUCTION AND USE OF HIGHLY FUNCTIONAL, HIGHLY BRANCHED OR HYPERBRANCHED POLYLYSINES 有权
Title translation: 高功能,高分子量或高分子量聚乙烯的生产和使用公开(公告)号:US20090048416A1
公开(公告)日:2009-02-19
申请号:US12093773
申请日:2006-11-15
Applicant: Bernd Bruchmann , Harm-Anton Klok , Markus Thomas Scholl
Inventor: Bernd Bruchmann , Harm-Anton Klok , Markus Thomas Scholl
CPC classification number: C07K14/001 , C08G83/005 , Y02P20/55 , Y10S977/754
Abstract: The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use.
Abstract translation: 本发明涉及新的高官能度,高支化或超支化聚赖氨酸,其制备方法及其应用。
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