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11.Cellulase variants with improved expression, activity and stability, and use thereof 有权
Title translation: 具有改善的表达,活性和稳定性的纤维素酶变体及其用途公开(公告)号:US08679816B2
公开(公告)日:2014-03-25
申请号:US13321928
申请日:2010-06-03
Applicant: Wolfgang Aehle , Richard R. Bott , Benjamin Bower , Jonathan Caspi , David A. Estell , Frits Goedegebuur , Ronaldus W. J. Hommes , Thijs Kaper , Bradley Kelemen , Slavko Kralj , Johan Van Lieshout , Igor Nikolaev , Sander Van Stigt Thans , Louise Wallace , Gudrun Vogtentanz , Mats Sandgren
Inventor: Wolfgang Aehle , Richard R. Bott , Benjamin Bower , Jonathan Caspi , David A. Estell , Frits Goedegebuur , Ronaldus W. J. Hommes , Thijs Kaper , Bradley Kelemen , Slavko Kralj , Johan Van Lieshout , Igor Nikolaev , Sander Van Stigt Thans , Louise Wallace , Gudrun Vogtentanz , Mats Sandgren
CPC classification number: C12N9/2437 , C12Y302/01091 , Y02E50/17
Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
Abstract translation: 本公开涉及纤维素酶变体。 特别地,本公开涉及具有改善的表达,活性和/或稳定性的纤维素酶变体。 还描述了编码纤维素酶变体的核酸,包含纤维素酶变体的组合物及其使用方法。
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公开(公告)号:US20120270298A1
公开(公告)日:2012-10-25
申请号:US13523800
申请日:2012-06-14
Applicant: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
Inventor: Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
IPC: C12N9/42
CPC classification number: C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Abstract translation: 本文描述的是H.jecorina CBH I,Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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13.CELLULASE VARIANTS WITH IMPROVED EXPRESSION, ACTIVITY AND STABILITY, AND USE THEREOF 有权
Title translation: 具有改进的表达,活性和稳定性的纤维素酶变体及其用途公开(公告)号:US20120135500A1
公开(公告)日:2012-05-31
申请号:US13321928
申请日:2010-06-03
Applicant: Wolfgang Aehle , Richard R. Bott , Benjamin Bower , Jonathan Caspi , David A. Estell , Frits Goedegebuur , Ronaldus W.J. Hommes , Thijs Kaper , Bradley Kelemen , Slavko Kralj , Johan Van Lieshout , Igor Nikolaev , Sander Van Stigt Thans , Louise Wallace , Gudrun Vogtentanz , Mats Sandgren
Inventor: Wolfgang Aehle , Richard R. Bott , Benjamin Bower , Jonathan Caspi , David A. Estell , Frits Goedegebuur , Ronaldus W.J. Hommes , Thijs Kaper , Bradley Kelemen , Slavko Kralj , Johan Van Lieshout , Igor Nikolaev , Sander Van Stigt Thans , Louise Wallace , Gudrun Vogtentanz , Mats Sandgren
IPC: C12N9/42
CPC classification number: C12N9/2437 , C12Y302/01091 , Y02E50/17
Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
Abstract translation: 本公开涉及纤维素酶变体。 特别地,本公开涉及具有改善的表达,活性和/或稳定性的纤维素酶变体。 还描述了编码纤维素酶变体的核酸,包含纤维素酶变体的组合物及其使用方法。
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