公开(公告)号：US20060005267A1

公开(公告)日：2006-01-05

申请号：US11056408

申请日：2005-02-11

Applicant: Steven Gutteridge ,  Yong Tao

Inventor： Steven Gutteridge ,  Yong Tao

IPC: A01H1/00 ,  C07H21/04 ,  C12P21/06 ,  C12N9/80 ,  C12N15/82 ,  C12N5/04

CPC classification number: C12N9/80

Abstract: This invention relates to an isolated nucleic acid fragment encoding a metalloprotease, more specifically peptide deformylase. The invention also relates to the construction of a recombinant DNA construct encoding all or a portion of peptide deformylase, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of peptide deformylase in a transformed host cell.

公开(公告)号：US06916971B1

公开(公告)日：2005-07-12

申请号：US10018902

申请日：2000-07-28

Applicant: Rebecca E. Cahoon ,  Steven Gutteridge ,  J. Antoni Rafalski

Inventor： Rebecca E. Cahoon ,  Steven Gutteridge ,  J. Antoni Rafalski

IPC: A01H1/00 ,  C07H21/04 ,  C07K14/415 ,  C12N5/14 ,  C12N9/00 ,  C12N9/02 ,  C12N9/90 ,  C12N15/82

CPC classification number: C12N9/0008 ,  C12N9/90 ,  C12N15/8243 ,  C12N15/8274

Abstract: This invention relates to an isolated nucleic acid fragment encoding an aminolevulinic acid biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the aminolevulinic acid biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the aminolevulinic acid biosynthetic enzyme in a transformed host cell.

Abstract translation: 本发明涉及编码氨基乙酰丙酸生物合成酶的分离的核酸片段。 本发明还涉及在正义或反义方向上编码全部或部分氨基乙酰丙酸生物合成酶的嵌合基因的构建，其中嵌合基因的表达导致转化的氨基乙酰丙酸生物合成酶水平的改变 宿主细胞。

公开(公告)号：US08101715B2

公开(公告)日：2012-01-24

申请号：US12635859

申请日：2009-12-11

Applicant: Timothy Caspar ,  Daniel Cordova ,  Steven Gutteridge ,  James J. Rauh ,  Lihong Wu ,  Yong Tao

Inventor： Timothy Caspar ,  Daniel Cordova ,  Steven Gutteridge ,  James J. Rauh ,  Lihong Wu ,  Yong Tao

IPC: C07K14/00 ,  A61K38/16

CPC classification number: C07K14/43563 ,  C07K14/705

Abstract: The genes encoding ryanodine receptor homologs have been characterized from multiple insect families including lepidopteran tobacco budworm (Heliothis virescens), homopteran green peach aphid (Myzus persicae), corn plant hopper (Peregrinus maidis), cotton melon aphid (Aphis gossypii) and fruitfly (Drosophila melanogaster). The full-length genes have been isolated, cloned and amplified in bacterial cells. Expression in insect cells shows that the recombinant protein folds into a functional calcium release channel. The genes and their corresponding polypeptides have a number of uses including, but not limited to, the isolation of other pest ryanodine receptors, the development of screens to identify insecticidally active compounds, use of fragments of genes as pesticides, fragments of protein for antibody production, fragments of protein for determination of the structure of insecticide binding sites, and identification of insecticides that disrupt the calcium balance in cells through other messengers that interact with the receptor calcium release mechanism. Methods are outlined for overcoming toxic effects of expressing recombinant proteins in host cells.

Abstract translation: 编码兰诺定受体同系物的基因已经被多种昆虫家族表征，包括鳞翅目叶烟芽夜蛾（Heliothis virescens），同翅目绿桃蚜虫（Myzus persicae），玉米植物漏斗（Peregrinus maidis），棉花蚜虫（Aphis gossypii）和果蝇 黑腹果蝇）。 全长基因已经在细菌细胞中被分离，克隆和扩增。 昆虫细胞中的表达显示重组蛋白折叠成功能性钙释放通道。 基因及其相应的多肽具有许多用途，包括但不限于分离其它害虫兰诺定受体，筛选鉴定杀虫活性化合物，使用基因片段作为农药，用于抗体生产的蛋白质片段 ，用于测定杀虫剂结合位点结构的蛋白质片段，以及鉴定通过与受体钙释放机制相互作用的其他信使破坏细胞中钙平衡的杀虫剂。 概述了克服在宿主细胞中表达重组蛋白的毒性作用的方法。

公开(公告)号：US20110008868A1

公开(公告)日：2011-01-13

申请号：US12922500

申请日：2009-04-03

Applicant: Howard Glenn Damude ,  Steven Gutteridge ,  Anthony J. Kinney ,  Michael W. Lassner ,  Daniel L. Siehl

Inventor： Howard Glenn Damude ,  Steven Gutteridge ,  Anthony J. Kinney ,  Michael W. Lassner ,  Daniel L. Siehl

IPC: C12N9/02 ,  C12N9/16

CPC classification number: C12N9/1085 ,  C07K2319/00 ,  C12N9/00 ,  C12N9/0004 ,  C12N9/0036 ,  C12N9/0071 ,  C12N9/0093 ,  C12N9/1029 ,  C12N9/16

Abstract: Multizymes (i.e., single polypeptides having at least two independent and separable enzymatic activities) are disclosed for a variety of applications beyond the synthesis of long chain polyunsaturated fatty acids.

Abstract translation: 公开了多长时间（即具有至少两个独立且可分离的酶活性的单一多肽），用于多种不同长链多不饱和脂肪酸合成之外的应用。

公开(公告)号：US07192758B2

公开(公告)日：2007-03-20

申请号：US10295220

申请日：2002-11-15

Applicant: Rebecca E. Cahoon ,  Steven Gutteridge ,  Steven Vollmer

Inventor： Rebecca E. Cahoon ,  Steven Gutteridge ,  Steven Vollmer

IPC: C12N9/90 ,  C12N1/18 ,  C12N15/70 ,  C12N21/06 ,  C07H21/04 ,  A01H3/00 ,  A01H9/00

CPC classification number: C12N9/1077 ,  C12N9/88 ,  C12N9/90 ,  C12P13/227

Abstract: This invention relates to isolated nucleic acid fragments encoding phosphoribosylanthranilate isomerases, a tryptophan biosynthetic enzyme. The invention also relates to the construction of a chimeric gene comprising the nucleic acid fragment, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the phosphoribosylanthranilate isomerase in a transformed host cell.

Abstract translation: 本发明涉及编码磷酸核糖基邻氨基苯甲酸异构酶，色氨酸生物合成酶的分离的核酸片段。 本发明还涉及在正义或反义方向上构建包含核酸片段的嵌合基因，其中嵌合基因的表达导致转化的宿主细胞中磷酸核糖基邻氨基苯甲酸异构酶水平的改变。

公开(公告)号：US07112722B2

公开(公告)日：2006-09-26

申请号：US10925178

申请日：2004-08-24

Applicant: Steven Gutteridge ,  Leslie T. Harvell

Inventor： Steven Gutteridge ,  Leslie T. Harvell

IPC: A01H1/00 ,  C07H21/04 ,  C07K14/415 ,  C12N5/14 ,  C12N9/00

CPC classification number: C12N9/93 ,  C12N15/8274

Abstract: This invention relates to isolated nucleic acid fragments encoding pantothenate synthetases. The invention also relates to the construction of chimeric genes encoding all or a portion of the pantothenate synthetases, in sense or antisense orientation, wherein expression of the chimeric genes results in production of altered levels of the pantothenate synthetases in transformed host cells.

公开(公告)号：US06881878B2

公开(公告)日：2005-04-19

申请号：US10033269

申请日：2001-11-13

Applicant: Steven Gutteridge ,  Leslie T. Harvell ,  Emil M. Orozco, Jr.

Inventor： Steven Gutteridge ,  Leslie T. Harvell ,  Emil M. Orozco, Jr.

IPC: C12N9/00 ,  C12N15/82 ,  A01H1/00 ,  C07H21/04 ,  C07K14/415 ,  C12N5/14

CPC classification number: C12N9/93 ,  C12N15/8274

Abstract: This invention relates to isolated nucleic acid fragments encoding pantothenate synthetases. The invention also relates to the construction of chimeric genes encoding all or a portion of the pantothenate synthetases, in sense or antisense orientation, wherein expression of the chimeric genes results in production of altered levels of the pantothenate synthetases in transformed host cells.

Abstract translation: 本发明涉及编码泛酸合成酶的分离的核酸片段。 本发明还涉及在正义或反义方向上编码全长或一部分泛酸合成酶的嵌合基因的构建，其中嵌合基因的表达导致转化宿主细胞中泛酸合成酶水平的变化。

公开(公告)号：US5471053A

公开(公告)日：1995-11-28

申请号：US264890

申请日：1994-06-24

Applicant: Bruce A. Diner ,  Steven Gutteridge ,  Gary L. Peterson ,  William E. Wolf

Inventor： Bruce A. Diner ,  Steven Gutteridge ,  Gary L. Peterson ,  William E. Wolf

IPC: G01J1/04 ,  G01J1/00 ,  G01J1/42

CPC classification number: G01J1/04 ,  G01J1/0418 ,  G01J1/0474 ,  G01J1/0488 ,  G01J2001/0481

Abstract: A light collector for use with a photodetector that provides uniform photodetector output response over a polar angular range regardless of the polar angle of incidence of light upon the collector is disclosed. The light collector comprises a generally spheroidally-shaped light direction changer having a light diffusing surface, and a generally spheroidally-shaped polar attenuator. The geometric center of the photosensitive surface of the photodetector is adjacent to the vertex of the generally spheroidally-shaped light direction changer.

Abstract translation: 公开了一种与光电检测器一起使用的集光器，该光电检测器在极化角度范围内提供均匀的光电检测器输出响应，而与集光器上的极的入射角无关。 光收发器包括具有光漫射表面的大致球形的光方向变换器和大体上呈球状的极性衰减器。 光电检测器的感光表面的几何中心与大致球形的光方向变换器的顶点相邻。

公开(公告)号：US08551694B2

公开(公告)日：2013-10-08

申请号：US13347091

申请日：2012-01-10

Applicant: Steven Gutteridge ,  Timothy Caspar ,  Daniel Cordova ,  James J. Rauh ,  Yong Tao ,  Lihong Wu

Inventor： Steven Gutteridge ,  Timothy Caspar ,  Daniel Cordova ,  James J. Rauh ,  Yong Tao ,  Lihong Wu

IPC: C12Q1/68 ,  G01N33/53

CPC classification number: C07K14/43563 ,  C07K14/705

Abstract: The genes encoding ryanodine receptor homologs have been characterized from multiple insect families. The genes and their corresponding polypeptides have a number of uses including but not limited to the development of screens to identify insecticidally active compounds. Methods are outlined for overcoming toxic effects of expressing recombinant proteins in host cells.

Abstract translation: 编码兰诺定受体同源物的基因已经被多个昆虫家族表征。 基因及其相应的多肽具有多种用途，包括但不限于筛选鉴定杀虫活性化合物的筛选。 概述了克服在宿主细胞中表达重组蛋白的毒性作用的方法。

公开(公告)号：US20130129839A1

公开(公告)日：2013-05-23

申请号：US13812304

申请日：2011-09-01

Applicant: Jeffrey Keith Long ,  Vann Gregory ,  Steven Gutteridge ,  Andrew Edmund Taggi ,  James Francis Bereznak

Inventor： Jeffrey Keith Long ,  Vann Gregory ,  Steven Gutteridge ,  Andrew Edmund Taggi ,  James Francis Bereznak

IPC: A01N43/56 ,  A01N43/54 ,  A01N43/40 ,  A01N43/653 ,  A01N43/78 ,  A01N43/84 ,  A01N43/90 ,  A01N43/50 ,  A01N59/20 ,  C07D231/38 ,  A01N43/42

CPC classification number: A01N43/56 ,  A01N37/34 ,  A01N37/44 ,  A01N43/12 ,  A01N43/26 ,  A01N43/30 ,  A01N43/40 ,  A01N43/42 ,  A01N43/48 ,  A01N43/50 ,  A01N43/54 ,  A01N43/653 ,  A01N43/78 ,  A01N43/80 ,  A01N43/84 ,  A01N43/90 ,  A01N47/08 ,  A01N47/12 ,  A01N47/28 ,  A01N59/20 ,  C07D231/20 ,  C07D231/38 ,  A01N37/38 ,  A01N37/46 ,  A01N43/36 ,  A01N45/02 ,  A01N47/04 ,  A01N47/14 ,  A01N47/24 ,  A01N47/34 ,  A01N47/38

Abstract: Disclosed is a fungicidal composition comprising (a) at least one compound selected from the compounds of Formula 1, N-oxides, and salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined in the disclosure; and (b) at least one additional fungicidal compound. Also disclosed is a method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof, or to the plant seed, a fungicidally effective amount of a compound of Formula 1, an N-oxide, or salt thereof (e.g., as a component in the aforesaid composition). Also disclosed is a composition comprising: (a) at least one compound selected from the compounds of Formula 1 described above, N-oxides, and salts thereof; and at least one invertebrate pest control compound or agent.