公开(公告)号：US10391290B2

公开(公告)日：2019-08-27

申请号：US15866526

申请日：2018-01-10

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Scott A. Burton ,  Chin-Yee Ng ,  Richard R. Mathias ,  Thomas D. R. Ford

IPC: A61M5/24 ,  A61M5/32 ,  A61M37/00

Abstract: A microneedle injection apparatus comprising a dual cover. The apparatus can include a housing having a base and a cavity; a microneedle array comprising a first side comprising a plurality of microneedles; and a microneedle array holder configured to hold a microneedle array and located in the housing. The microneedle array holder can be movable between a retracted position, and an extended position. The apparatus can further include a cover configured to be positioned to cover the opening in the base of the housing. The cover can include (i) a first portion configured to cover at least a portion of the base of the housing adjacent the opening, and (ii) a second portion configured to be received in the cavity of the housing and further configured to cover the plurality of microneedles on the microneedle array when the microneedle array holder is in the retracted position.

公开(公告)号：US10327990B2

公开(公告)日：2019-06-25

申请号：US15537040

申请日：2015-12-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Marc A. Egeland ,  Chin-Yee Ng ,  Jo A. Etter ,  Ravi Kolakaluri

IPC: A61J1/20 ,  A61M5/24 ,  A61M5/28 ,  A61M5/31 ,  A61M5/315

Abstract: A container for storing and mixing two components is provided. The container includes a body, a first plug, and a second plug. The body has a first end, a second end, and a bypass with a length L disposed between the first and second ends. The first and second plugs are slidably disposed in the body and define a first compartment. A second compartment is in the body between the second plug and the second end. The second plug has a first edge, a second edge, and a primary conduit extending therein, a plurality of secondary conduits extending from the primary conduit through the second plug. The primary conduit has a first opening. A distance D extends longitudinally from the first edge to the second edge and a distance E extends longitudinally from the first edge to the first opening. D≥L and E

公开(公告)号：US20180110970A1

公开(公告)日：2018-04-26

申请号：US15838542

申请日：2017-12-12

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Scott A. Burton ,  Chin-Yee Ng ,  Michael J. Frits ,  Richard R. Mathias

IPC: A61M37/00 ,  A61M5/32 ,  A61M5/142

CPC classification number: A61M37/0015 ,  A61M5/14248 ,  A61M5/322 ,  A61M5/3297 ,  A61M2037/0023 ,  A61M2037/0061

Abstract: A microneedle injection and infusion apparatus, and a method of using same. The apparatus can include a housing, a microneedle array holder for holding a microneedle array, and a shuttle that holds a cartridge (e.g., that contains an active agent). The microneedle array holder can be movable between a retracted position and an extended position. The shuttle can be movable between a first position in which the cartridge is not in fluid communication with a fluid path and a second position in which the cartridge is in fluid communication with the fluid path. The apparatus can further include an actuator movable between a first position and a second position. The method can include moving the actuator to its second position to allow the shuttle to move toward its second position, wherein movement of the shuttle toward its second position allows the microneedle array holder to move to its extended position.

公开(公告)号：US20140243786A1

公开(公告)日：2014-08-28

申请号：US14342554

申请日：2012-09-06

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Thomas J. Gilbert ,  Chin-Yee Ng ,  Scott A. Burton ,  Michael C. Molinet ,  Robert A. Harkins ,  Bernard A. Gonzalez ,  Larry A. Schleif ,  Patrick J. Young

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A61M5/14248 ,  A61M5/1454 ,  A61M2005/1585 ,  A61M2037/0023 ,  A61M2037/003 ,  A61M2037/0061

Abstract: The present disclosure relates to systems and methods for delivering microneedles to a patient's skin. In one aspect, the present disclosure provides a system for delivering a microneedle array to a patient's skin surface, the system comprising: a delivery apparatus including a housing; and an infusion device detachably received in the housing.

Abstract translation: 本公开涉及将微针输送到患者皮肤的系统和方法。 一方面，本公开提供了一种用于将微针阵列递送到患者皮肤表面的系统，该系统包括：输送设备，包括壳体; 以及可拆卸地容纳在所述壳体中的输注装置。

公开(公告)号：USD693921S1

公开(公告)日：2013-11-19

申请号：US29435645

申请日：2012-10-26

Applicant: 3M Innovative Properties Company

Designer： Scott A. Burton ,  Elizabeth A. Marshall ,  Richard R. Mathias ,  Chin-Yee Ng

公开(公告)号：US10695547B2

公开(公告)日：2020-06-30

申请号：US15597235

申请日：2017-05-17

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Scott A. Burton ,  Chin-Yee Ng ,  Richard R. Mathias

IPC: A61M37/00 ,  A61M5/32 ,  A61B5/15

Abstract: A microneedle injection apparatus comprising an inverted actuator. The apparatus can include a housing having a base and a cavity, and a microneedle array holder configured to hold a microneedle array within the cavity of the housing. The microneedle array holder can be movable between a retracted position, and an extended position. The apparatus can further include an actuator movable with respect to the housing and the microneedle array holder between a first position and a second position to cause the microneedle array holder to move from the retracted position to the extended position. At least a portion of the actuator can be located on a skin-facing side of the apparatus (e.g., adjacent the base of the housing) and can be configured to be moved from the first position to the second position in response to the apparatus being pressed toward the skin surface.

公开(公告)号：US10549079B2

公开(公告)日：2020-02-04

申请号：US14652146

申请日：2013-12-06

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Scott A. Burton ,  Chin-Yee Ng

IPC: A61M37/00

Abstract: Adhesive assemblies and microneedle injection apparatuses comprising same. The apparatus (100) can include a housing (102) having a base and an opening (115) formed in the base; and an applicator comprising a microneedle array (104), the microneedle array comprising a first major surface (111) and microneedles (105). The applicator can be movable between a first position, and a second position in which at least a portion of the microneedle array extends through the opening in the base. The apparatus can further include an adhesive assembly (118), which can be adhered to the base of the housing. The adhesive assembly can include an extension (125) that extends at least partially into the area defined by the opening, such that when the applicator is in the second position, at least a portion of the first major surface of the microneedle array is in contact with the extension of the adhesive assembly.

公开(公告)号：US10201691B2

公开(公告)日：2019-02-12

申请号：US14904998

申请日：2014-07-10

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Dennis G. Berry ,  Paul A. Martinson ,  Chin-Yee Ng ,  Ryan Patrick Simmers

IPC: A61M37/00

Abstract: An article 100 comprising at least one microneedle 160 is provided. The article comprises a first side 112 and a second side 114 opposite the first side. The first side comprises a central cavity portion 120 and a platform portion 130, with at least one microneedle extending therefrom, wherein the platform portion is not coplanar with the central cavity portion. The platform portion substantially surrounds the central cavity portion. The at least one microneedle 160 comprises a body comprising an outer surface 163; a base segment 166 having a base and a first shape; a tip segment 168 having a tip 164 and a second shape, wherein the second shape is distinct from the first shape; a transition plane 167 that delineates the base segment and the tip segment; and a central axis.

公开(公告)号：US20170252547A1

公开(公告)日：2017-09-07

申请号：US15597235

申请日：2017-05-17

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Scott A. Burton ,  Chin-Yee Ng ,  Richard R. Mathias

IPC: A61M37/00 ,  A61M5/32

Abstract: A microneedle injection apparatus comprising an inverted actuator. The apparatus can include a housing having a base and a cavity, and a microneedle array holder configured to hold a microneedle array within the cavity of the housing. The microneedle array holder can be movable between a retracted position, and an extended position. The apparatus can further include an actuator movable with respect to the housing and the microneedle array holder between a first position and a second position to cause the microneedle array holder to move from the retracted position to the extended position. At least a portion of the actuator can be located on a skin-facing side of the apparatus (e.g., adjacent the base of the housing) and can be configured to be moved from the first position to the second position in response to the apparatus being pressed toward the skin surface.

公开(公告)号：US09682222B2

公开(公告)日：2017-06-20

申请号：US14892238

申请日：2014-05-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Scott A. Burton ,  Chin-Yee Ng ,  Richard R. Mathias

IPC: A61M37/00 ,  A61M5/32

CPC classification number: A61M37/0015 ,  A61B5/150022 ,  A61B5/150984 ,  A61M5/322 ,  A61M2037/0023 ,  A61M2037/0061

Abstract: A microneedle injection apparatus (100) comprising an inverted actuator. The apparatus can include a housing (102) having a base and a cavity, and a microneedle array holder (106) configured to hold a microneedle array (107) within the cavity of the housing. The microneedle array holder can be movable between a retracted position, and an extended position. The apparatus can further include an actuator (104) movable with respect to the housing and the microneedle array holder between a first position and a second position to cause the microneedle array holder to move from the retracted position to the extended position. At least a portion of the actuator can be located on a skin-facing side of the apparatus (e.g., adjacent the base of the housing) and can be configured to be moved from the first position to the second position in response to the apparatus being pressed toward the skin surface.