公开(公告)号：US11246808B2

公开(公告)日：2022-02-15

申请号：US16074655

申请日：2017-02-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Bradley D. Craig ,  Timothy D. Dunbar ,  Karsten Dede ,  Adrian S. Eckert ,  Ahmed S. Abuelyaman ,  Gregory A. Kobussen ,  Christoph H. Thalacker ,  Paul J. Homnick

IPC: A61K6/818 ,  A61K6/16 ,  A61K6/17 ,  A61K6/71 ,  A61K6/76 ,  A61K6/78 ,  A61K6/887

Abstract: Dental compositions and methods of formulating a dental composition are described. In one embodiment, the dental composition comprises a polymerizable resin comprising one or more ethylenically unsaturated monomers or oligomers and nano-particles. The nanoparticles have a refractive index of at least 1.600 and an average discrete or aggregate particle size of no greater than 100 nm. The dental composition further comprises inorganic metal oxide filler having a discrete or aggregate average particle size of at least 200 nm. The nanoparticles are present at a concentration to provide a refractive index differential between the cured polymerizable resin and inorganic metal oxide filler such that the contrast ratio of the dental composition is at least 40.

公开(公告)号：US10932995B2

公开(公告)日：2021-03-02

申请号：US16762170

申请日：2018-11-05

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Adrian S. Eckert ,  Karsten Dede ,  Christoph H. Thalacker ,  Gioacchino Raia

IPC: A61K6/891 ,  C07C69/007 ,  A61C13/00

Abstract: The invention relates to a dental composition comprising a resin matrix, a filler matrix in an amount of at least 25 wt. % with respect to the weight of the dental composition, an initiator system, the resin matrix comprising polymerizable monomer(s) comprising two (meth)acrylate moieties connected to a brominated resorcinol, catechol, tyrosol, benzoic acid or phenol moiety. The invention relates also to a dental milling block comprising this composition in its hardened stage.

公开(公告)号：US20190038516A1

公开(公告)日：2019-02-07

申请号：US16074655

申请日：2017-02-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Bradley D. Craig ,  Timothy D. Dunbar ,  Karsten Dede ,  Adrian S. Eckert ,  Ahmed S. Abuelyaman ,  Gregory A. Kobussen ,  Christoph H. Thalacker ,  Paul J. Homnick

IPC: A61K6/02 ,  A61K6/00 ,  A61K6/083

Abstract: Dental compositions and methods of formulating a dental composition are described. In one embodiment, the dental composition comprises a polymerizable resin comprising one or more ethylenically unsaturated monomers or oligomers and nano-particles. The nanoparticles have a refractive index of at least 1.600 and an average discrete or aggregate particle size of no greater than 100 nm. The dental composition further comprises inorganic metal oxide filler having a discrete or aggregate average particle size of at least 200 nm. The nanoparticles are present at a concentration to provide a refractive index differential between the cured polymerizable resin and inorganic metal oxide filler such that the contrast ratio of the dental composition is at least 40.

公开(公告)号：US20170165152A1

公开(公告)日：2017-06-15

申请号：US15116873

申请日：2015-02-10

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Adrian S. Eckert ,  Michael Cub ,  Bettina Hailand ,  Marion B. Kestel ,  Christoph Thalacker ,  Karsten Dede

IPC: A61K6/083 ,  A61C13/00 ,  A61K6/00

CPC classification number: A61K6/0835 ,  A61C13/0022 ,  A61K6/0052 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/083 ,  C08L75/16

Abstract: A dental composition comprising a polymerizable monomer (1), initiator, filler component(s) in an amount of more than about 20 wt.-%, wt.-% with respect to the whole weight of the composition, the polymerizable monomer (1) being characterized as follows: having exactly two (meth)acrylate reactive moieties, having an unsymmetrical backbone as linkage between the (meth)acrylate reactive moieties, the two (meth)acrylate reactive moieties being attached onto the unsymmetrical monomer backbone as alkyl esters, the unsymmetrical backbone comprising one aromatic moiety of the phenolic type, the polymerizable monomer (1) not containing an acidic moiety, other atoms than carbon, hydrogen, nitrogen, and oxygen, a bisphenol moiety. The invention is also directed to the use of the dental composition as or for producing a dental filling material, dental cement, crown and bridge material, inlay, onlay, veneer, orthodontic device or dental mill blank

公开(公告)号：US20170065495A1

公开(公告)日：2017-03-09

申请号：US15119172

申请日：2015-02-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Adrian S. Eckert ,  Michael Cub ,  Bettina Hailand ,  Ines Edelmann ,  Christoph Thalacker ,  Karsten Dede ,  Uwe H. Hoheisel ,  Reinhold Hecht

IPC: A61K6/00

CPC classification number: A61K6/0023 ,  A61K6/0052 ,  A61K6/0088 ,  C08L33/10 ,  C08L33/08

Abstract: An adhesive dental composition comprising a polymerizable monomer (1), a polymerizable monomer (2) comprising an acidic moiety, initiator component(s), filler component(s) in an amount of less than about 15 wt.-%, wt.-% with respect to the whole weight of the composition, the polymerizable monomer (1) being characterized as follows: having exactly two (meth)acrylate reactive moieties, having an unsymmetrical backbone as linkage between the (meth)acrylate reactive moieties, the two (meth)acrylate reactive moieties being attached onto the unsymmetrical monomer backbone as alkyl esters, the unsymmetrical backbone comprising one aromatic moiety of the phenolic type, the polymerizable monomer (1) not containing an acidic moiety, other atoms than carbon, hydrogen, and oxygen, bisphenol moieties. The invention also relates to the use of the adhesive dental composition as dental adhesive, sealant, cement or for bonding or cementing a material to the surface of hard dental tissue.

Abstract translation: 一种粘合剂牙科用组合物，其包含可聚合单体（1），包含酸性部分的可聚合单体（2），引发剂组分，少于约15重量％的量的填料组分， 相对于组合物的整个重量，可聚合单体（1）的特征如下：具有正好两个（甲基）丙烯酸酯反应性部分，在（甲基）丙烯酸酯反应性部分之间具有不对称主链作为连接， 甲基）丙烯酸酯反应性部分作为烷基酯连接到非对称单体骨架上，不对称骨架包含一种酚类芳族部分，不含酸性部分的可聚合单体（1），除碳，氢和氧以外的其它原子， 双酚部分。 本发明还涉及粘合剂牙科组合物作为牙科粘合剂，密封剂，水泥或用于将材料粘结或粘合到硬牙齿组织表面上的用途。